Tobacco Smoking clinical trials
The registry lists 264 studies for Tobacco Smoking across more than 10 countries. 42 are recruiting or about to start. 142 of them are mainly about Tobacco Smoking (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its narrower condition Cigarette Smoking too: 696 studies, 123 open.
Get an email when these change. Save the Tobacco Smoking studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
RAI Services Company (29) · Johns Hopkins University (10) · University of California, San Francisco (8) · Juul Labs, Inc. (8) · Massachusetts General Hospital (8) · Wake Forest University Health Sciences (5) · University of Houston (5) · University of Minnesota (4)
What is being tested here
Drugs under test in Tobacco Smoking studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction · University of Pennsylvania
- Nov 2026THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTS · Seher DÖNER
- Nov 2026Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal · Johns Hopkins Bloomberg School of Public Health
- Nov 2026ACT Lung Health Intervention: Phase Two · Dana-Farber Cancer Institute
- Dec 2026Vaping Cessation Using the Ottawa Model for Smoking Cessation Among E-Cigarette Users · Ottawa Heart Institute Research Corporation
- Dec 2026A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers · RAI Services Company
- Dec 2026Oral Cannabidiol for Tobacco Cessation · Johns Hopkins University
- Dec 2026A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers · RAI Services Company
- Dec 2026Trauma-Informed Care for Smoking Cessation for Pregnancy · University of California, San Francisco
- Dec 2026Cannabidiol for Reducing Cigarette Use · University of California, Los Angeles
Who these studies take
Of the 33 Tobacco Smoking studies recruiting now, 15 (45%) set no upper age limit and 16 (48%) stop at 75 or younger. 2 (6%) take children under 18. 2 (6%) are for women only and 0 (0%) for men only; 16 (48%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 25 (76%) | 23 (70%) |
| 30 | 30 (91%) | 28 (85%) |
| 40 | 30 (91%) | 28 (85%) |
| 50 | 29 (88%) | 28 (85%) |
| 65 | 27 (82%) | 26 (79%) |
| 75 | 18 (55%) | 17 (52%) |
| 85 | 17 (52%) | 16 (48%) |
Across all 264 studies, recruiting or not: 50% stop at 75 or younger and 44% at 65; 9% take children; 3% are for women only and <1% for men only; 67% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tobacco Smoking studies take
Of 151 interventional studies with no phase under Tobacco Smoking, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 16 mo4–29 · 151 studies | 2 mo1–4 · 39 studies | 24 mo13–35 · 112 studies |
| Observational | 36 mo3–112 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Results posted1
- Tobacco Cessation at FDNYNov 5, 2026NCT05997225
Newly registered3
- COPD Prevalence and Risk Factors Among Saudi Adults Over 18 in TaifOct 21, 2026NCT07886346
- THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTSOct 21, 2026NCT07887217
- A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery SystemOct 19, 2026NCT07879638
Studies
Recruiting first, then most recently updated. Showing 50 of 264. Browse all 264 → or search them.
- A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery SystemRecruitingNCT07879638Not applicable1 country
- Trauma-Informed Care for Smoking Cessation for PregnancyRecruitingNCT07129590Not applicable1 country
- A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free HomeRecruitingNCT06693700Not applicable1 country
- Efficacy of the Proactive Automatized Lifestyle InterventionRecruitingNCT07441603Not applicable1 country
- The SMOKE Telehealth StudyRecruitingNCT07743710Not applicable1 country
- Effects of Cannabidiol on Stress and Nicotine WithdrawalRecruitingNCT07001930Phase 11 country
- A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette SmokersRecruitingNCT07710820Not applicable1 country
- Abuse Liability of Four Modern Oral Nicotine ProductsNot yet recruitingNCT07685795Not applicable
- A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within SmokersRecruitingNCT07598136Not applicable1 country
- Reduce Tobacco Use in People Living With HIV in SwitzerlandRecruitingNCT06789692Not applicable1 country
- The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded StudyRecruitingNCT065358671 country
- Abuse Liability of Two Modern Oral Nicotine Pouched ProductsNot yet recruitingNCT07595055Not applicable
- Effects of CO Level on Pain, Sensory Function, and Subjective HealthNot yet recruitingNCT07571941
- Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in AppalachiaRecruitingNCT05660525Not applicable1 country
- Cannabidiol for Reducing Cigarette UseRecruitingNCT06218056Phase 21 country
- Smoking Harm Reduction Using E-cigarettes and CytisineNot yet recruitingNCT07274475Not applicable
- Smoking Cessation and Menstrual Cycle PhaseRecruitingNCT05515354Phase 41 country
- ACT Lung Health Intervention: Phase TwoRecruitingNCT06945120Not applicable1 country
- Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young AdultsRecruitingNCT07398443Not applicable1 country
- Oral Cannabidiol for Tobacco CessationRecruitingNCT05445804Phase 11 country
- A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery SystemsNot yet recruitingNCT07323563Not applicable
- Abuse Liability for Eight Electronic Nicotine ProductsNot yet recruitingNCT07323511Not applicable
- Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic DiseaseRecruitingNCT07039175Phase 31 country
- Abuse Liability for Five Modern Oral Nicotine ProductsRecruitingNCT07132814Not applicable1 country
- Abuse Liability for Four Heated Tobacco Product (HTP) Consumables and Two HTP DevicesNot yet recruitingNCT07267195Not applicable
- Buteyko Breathing and Approach of Smoking Hygiene: Effects on Dysfucntion of Eustachian Tube and Lung FunctionsRecruitingNCT07236580Not applicable1 country
- tDCS Plus Varenicline for Smoking CessationRecruitingNCT06798324Phase 41 country
- Respiratory Function and Oxygenation in Smokers and Non-smokersRecruitingNCT070279561 country
- V+PSF-M for Tobacco Cessation in HIV Care in IndiaRecruitingNCT05786547Phase 32 countries
- Reach Through Equitable Implementation in UtahRecruitingNCT06881069Not applicable1 country
- Smoke-free Home Study in Subsidized HousingRecruitingNCT06170437Not applicable1 country
- INSPIRE Respiratory Health Program in Botucatu, São Paulo, BrazilRecruitingNCT066732251 country
- Enhancing Equity in Smoke-free HousingEnrolling by invitationNCT06042361Not applicable1 country
- Persistent Poverty Counties Pregnant Women With MedicaidEnrolling by invitationNCT05415371Not applicable1 country
- Cue Effects in Human Addiction: Pavlovian to Instrumental TransferRecruitingNCT059922721 country
- Brief Behavioural Economic Intervention for Smoking CessationRecruitingNCT06451081Not applicable1 country
- Lung Cancer Screening in a Population Exposed to Occupational Lung CarcinogensRecruitingNCT035620521 country
- Effects of Post-isometric Relaxation Technique on Chest Expansion and Pulmonary Function Tests in SmokersRecruitingNCT06444971Not applicable1 country
- Development of a Smoking Cessation Video SeriesRecruitingNCT06443294Not applicable1 country
- Effectiveness of Combined Tobacco Treatment in Hospitalized SubjectsRecruitingNCT06254001Phase 41 country
- The Effect of Electronic Cigarette Use on Smoking Behaviors Among Smokers Receiving Outpatient Psychiatric TreatmentRecruitingNCT04014322Not applicable1 country
- Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as CorrelatesRecruitingNCT03495024Phase 41 country
- CONNECT Cancer Survivors With Tobacco TreatmentActive, not recruitingNCT07020273Not applicable1 country
- Vaping Cessation Using the Ottawa Model for Smoking Cessation Among E-Cigarette UsersActive, not recruitingNCT06164678Not applicable1 country
- Tobacco Cessation at FDNYCompletedNCT05997225Phase 41 country
- COPD Prevalence and Risk Factors Among Saudi Adults Over 18 in TaifCompletedNCT078863461 country
- The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy EvaluationCompletedNCT055541201 country
- THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTSActive, not recruitingNCT07887217Not applicable1 country
- App for Pregnancy Smoking Cessation With Peer SupportCompletedNCT05337722Not applicable1 country
- Urban Exposome and Biological AgeCompletedNCT078178361 country