Drug class
Cholinesterase Inhibitors clinical trials
A class of medicines: the studies that test any of its 18 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the cholinesterase inhibitors studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Echothiophate Iodide
- 2
- Phenserine
- 1
- Edrophonium
- 1
- Mimopezil
- 1
- Methanesulfonyl fluoride
- 1
- Benzgalantamine gluconate
- 1
- Tacrine
- 1
Studies by the year they started
494 studies that test it; most in 2009 (33); 1 more planned to start later
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 2 |
| 1998 | 1 |
| 1999 | 3 |
| 2000 | 5 |
| 2001 | 10 |
| 2002 | 15 |
| 2003 | 19 |
| 2004 | 27 |
| 2005 | 18 |
| 2006 | 22 |
| 2007 | 32 |
| 2008 | 32 |
| 2009 | 33 |
| 2010 | 14 |
| 2011 | 28 |
| 2012 | 20 |
| 2013 | 18 |
| 2014 | 27 |
| 2015 | 18 |
| 2016 | 13 |
| 2017 | 23 |
| 2018 | 14 |
| 2019 | 18 |
| 2020 | 11 |
| 2021 | 13 |
| 2022 | 8 |
| 2023 | 13 |
| 2024 | 17 |
| 2025 | 8 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Dementia
- 20
Who runs them
Industry 181 · Other 324
Eisai Inc. (20) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (16) · Novartis (13) · Novartis Pharmaceuticals (12) · Eisai Co., Ltd. (11) · Ain Shams University (8) · Assiut University (8) · University of Maryland, Baltimore (8)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 505
- An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia NervosaNot yet recruitingPhase 2New York State Psychiatric InstituteNCT06518941Written as Donepezil
- Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney DiseaseRecruitingPhase 4The University of Texas Medical Branch, GalvestonNCT07203287Written as Neostigmine
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)RecruitingPhase 4Alpha Cognition, IncNCT07633470Written as Zunveyl®
- LIFT: Life Improvement TrialRecruitingPhase 2Brigham and Women's HospitalNCT06366724Written as Pyridostigmine
- Effect of Acetylcholinesterase Inhibitors on Bone MetabolismRecruitingPhase 2Duke UniversityNCT06041789Written as Donepezil
- Pharmacokinetics of Huperzine A Oral Solution in Healthy ParticipantsNot yet recruitingPhase 1Wanbangde Pharmaceutical Group Co., LTDNCT07784335Written as Huperzine A Oral Solution
- A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2511 in Participants With Early Alzheimer's Disease (AD)Not yet recruitingPhase 1Eisai Inc.NCT07768592Written as Donepezil
- The Study of Ginkgo Leaf Dropping Pills and Huperzine A Injection Combined With Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain InjuryRecruitingPhase 4Wanbangde Pharmaceutical Group Co., LTDNCT06704334Written as Huperzine A injection
- Rivastigmine for Antimuscarinic DeliriumRecruitingPhase 2Washington University School of MedicineNCT06382649Written as Rivastigmine
- Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)RecruitingPhase 2/3Northwell HealthNCT07625332Written as Galantamine Hydrobromide Extended Release
- Pharmacological Reversal of Neuromuscular Blockade in Critically Ill PatientsRecruitingNot applicableSeoul National University HospitalNCT05993390Written as Neostigmine
- Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African AmericansRecruitingPhase 1/2Vanderbilt University Medical CenterNCT04769206Written as Galantamine
- Evaluation of Echothiophate in Pediatric Patients With Refractory AmblyopiaNot yet recruitingPhase 2University of OklahomaNCT07554131Written as Echothiophate Iodide 0.125% Ophthalmic Solution
- Antagonism of Neostigmine in Continuous Infusion of MivacuriumNot yet recruitingNot applicableBeijing Tongren HospitalNCT07524959Written as Neostigmine
- Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural PunctureRecruitingPhase 2Mayo ClinicNCT05116930Written as Neostigmine
- Comparing Acotiamide and Itopride for the Management of IndigestionNot yet recruitingPhase 4Aga Khan UniversityNCT07449689Written as Acotiamide
- A Study of Pyridostigmine in Postural Tachycardia SyndromeRecruitingPhase 2Mayo ClinicNCT00409435Written as pyridostigmine
- Pyridostigmine for the Treatment of Constipation in Parkinson DiseaseRecruitingPhase 2University of Vermont Medical CenterNCT05603715Written as Pyridostigmine Bromide
- Donepezil Versus Non-drug Treatment in Alzheimer's Disease.RecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT04661280Written as Donepezil
- Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal SurgeryRecruitingPhase 2/3Stefan Holubar MD MS FACS, FASCRSNCT05334485Written as Pyridostigmine Bromide
See all 505 studies that test one of the cholinesterase inhibitors →
Codes
What other systems call Cholinesterase Inhibitors · ClinicalTrials.gg INT007215
- MeSH (NLM) D002800Cholinesterase InhibitorsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002800 | Cholinesterase Inhibitors | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.