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Sleep Wake Disorders clinical trials

The registry lists 747 studies for Sleep Wake Disorders across more than 10 countries. 182 are recruiting or about to start. 240 of them are mainly about Sleep Wake Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 16 narrower conditions too, such as Sleep Initiation and Maintenance Disorders: 7,110 studies, 1,597 open.

ClinicalTrials.gov finds 7,501 studies for Sleep Wake Disorders. How that becomes 747 here

This page counts the studies the registry files under Sleep Wake Disorders, and those it files under no condition that list Sleep Wake Disordersthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 7,501Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −6,221Filed under a narrower condition, counted on its own pageSleep Initiation and Maintenance Disorders 2,507 · Sleep Apnea, Obstructive 2,073 · Sleep Apnea Syndromes 641 · Sleep Deprivation 253 · Restless Legs Syndrome 215 · Disorders of Excessive Somnolence 107 · 10 more
  3. −2List Sleep Wake Disorders as a condition, but the registry did not file them under itMost often written as “Sleep-wake Disorder in Blind Individuals” (1) and “Circadian Rhythm Sleep-Wake Disorders, Unspecified Type” (1). The registry filed 1 of them under no condition at all, and the others under other conditions only, most often Blindness (1).
  4. −531Match it another way531 by a synonym or other text the search reads.
  5. 747The count on this page

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Status

Completed
405
Recruiting
109
Status unknown
84
Not yet recruiting
63
Terminated
35
Active, not recruiting
26

Phase

Phase 3
52
Phase 4
50
Phase 2
49
Phase 1
17
Early Phase 1
5

Where

United States
248
France
65
China
46
Turkey
46
Canada
37
Italy
28

Who runs them

University of California, Berkeley (9) · Massachusetts General Hospital (9) · Brigham and Women's Hospital (8) · US Department of Veterans Affairs (8) · Vanda Pharmaceuticals (7) · Cairo University (7) · University of California, San Diego (7) · VA Office of Research and Development (7)

What is being tested here

Drugs under test in Sleep Wake Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Berobenatide222
Melatonin1417
Mirtazapine167
Tasimelteon166
Dexmedetomidine104
Trazodone124
Alixorexton113
Pregabalin113
Esketamine101
Oxybate101

Drug classes tested here Stimulants 4 · Corticosteroids 4 · Dopamine agonists 4 · Cholinesterase inhibitors 3 · SNRIs 3

Coming up

12phase 3 studies under way
68studies finish main data collection within a year5 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 109 Sleep Wake Disorders studies recruiting now, 36 (33%) set no upper age limit and 53 (49%) stop at 75 or younger. 22 (20%) take children under 18. 9 (8%) are for women only and 0 (0%) for men only; 24 (22%) take healthy volunteers.

Recruiting studies that take each age, of 109
AgeWomenMen
1018 (17%)17 (16%)
1873 (67%)67 (61%)
3079 (72%)71 (65%)
4081 (74%)74 (68%)
5086 (79%)80 (73%)
6585 (78%)79 (72%)
7562 (57%)58 (53%)
8543 (39%)40 (37%)

Across all 747 studies, recruiting or not: 46% stop at 75 or younger and 35% at 65; 17% take children; 8% are for women only and 1% for men only; 29% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Sleep Wake Disorders studies take

Of 19 phase 3 interventional studies under Sleep Wake Disorders, half reached primary completion within 37 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 237 mo15–57 · 14 studies——
Phase 337 mo25–60 · 19 studies——
Phase 429 mo20–31 · 13 studies——
Interventional, no phase19 mo6–37 · 243 studies12 mo5–22 · 35 studies21 mo7–40 · 208 studies
Observational25 mo12–43 · 82 studies—29 mo12–47 · 71 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Newly registered7

Show 2 more

Studies

Recruiting first, then most recently updated. Showing 50 of 747. Browse all 747 → or search them.