Drug
Oxybate clinical trials
Also written GHB.
Includes 41 studies of Sodium Oxybate.
- studies test it
- 44
- open now
- 4
- in phase 3
- 12
- first study started
- 2000
Keep track of what changes. Save the oxybate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
- GHB
- 2
Studies by the year they started
43 studies that test it; most in 2006 (5)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 3 |
| 2005 | 1 |
| 2006 | 5 |
| 2007 | 4 |
| 2008 | 2 |
| 2009 | 1 |
| 2010 | 1 |
| 2012 | 2 |
| 2013 | 2 |
| 2014 | 3 |
| 2015 | 1 |
| 2016 | 1 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 3 |
| 2021 | 1 |
| 2025 | 1 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 16
- Phase 3
- 12
- Phase 4
- 11
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 29
Jazz Pharmaceuticals (10) · Kristina Simonyan (3) · Stanford University (3) · Orphan Medical (2) · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (1) · Poitiers University Hospital (1) · University Hospital, Montpellier (1) · Baylor College of Medicine (1)
Often tested with
Tested in the same studies.
Cobicistat (1) · Zolpidem (1) · Modafinil (1) · Triazolam (1) · Pentobarbital (1)
Studies
Open first, then newest update. How each study uses oxybate is read from its arms, and is right about nine times in ten.
Testing it · 44
- Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic SurgeryRecruitingNot applicableJingsheng LouNCT07794982Written as sodium oxybate
- Electrophysiological Analysis of Gamma-Hydroxybutyrate-induced Sleep in Intensive Care PatientsNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT07596342Written as GHB
- Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice TremorNot yet recruitingPhase 1Kristina SimonyanNCT07041203Written as sodium oxybate
- Extended-release Sodium Oxybate in ChildrenRecruitingPhase 2Stanford UniversityNCT06809803Written as Extended-release sodium oxybate
- Sodium Oxybate Versus Midazolam for Comfort SedationCompletedPhase 4Centre Hospitalier Intercommunal de Toulon La Seyne sur MerNCT05085873Written as Sodium Oxybate injection
- Sodium Oxybate in Spasmodic Dysphonia and Voice TremorCompletedPhase 2/3Kristina SimonyanNCT03292458Written as Sodium Oxybate
- Impact of Gamma-OH on Sleep in ICU PatientsCompletedPhase 2Poitiers University HospitalNCT04224246Written as Gamma Hydroxybutyrate
- Sodium Oxybate in Idiopathic HypersomniaCompletedPhase 2/3University Hospital, MontpellierNCT03597555Written as Sodium Oxybate Oral Solution 500 MG/ML
- Treatment of REM Sleep Behavior Disorder (RBD) With Sodium OxybateCompletedPhase 4Stanford UniversityNCT04006925Written as Sodium Oxybate
- Sodium Oxybate in Patients With Chronic Fatigue Syndrome.WithdrawnPhase 4University Hospital, GhentNCT01584934Written as Sodium oxybate
- Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD)CompletedPhase 2Baylor College of MedicineNCT00641186Written as sodium oxybate
- Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine ChangesCompletedPhase 1UCB Pharma SANCT00345800Written as Sodium Oxybate (Xyrem)
- Xyrem and Brain Dopamine in NarcolepsyCompletedPhase 4Centre for Addiction and Mental HealthNCT02637076Written as Xyrem
- Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic HypersomniaWithdrawnEarly Phase 1Brigham and Women's HospitalNCT03626727Written as Sodium Oxybate Oral Solution [Xyrem]
- Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson's DiseaseCompletedPhase 2Christian BaumannNCT02111122Written as Sodium Oxybate
- Evaluation of the Efficacy of Sodium Oxybate in the Long-term Maintenance of Abstinence in Alcoholic PatientsCompletedPhase 4Laboratorio Farmaceutico Ct S.r.l.NCT04648423Written as Sodium Oxybate
- SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE)CompletedPhase 4Imperial College LondonNCT02055898Written as Sodium Oxybate
- Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and CobicistatCompletedPhase 1Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la CienciaNCT04322214Written as GHB
- Characterization of the Prosocial and Prosexual Effects of GHBCompletedNot applicableUniversity of ZurichNCT02342366Written as GHB 35 mg/kg p.o.
- A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With CataplexyCompletedPhase 3Jazz PharmaceuticalsNCT02221869Written as Xyrem
See all 44 studies that test oxybate →
Given in every arm · 1 — oxybate is usual care beside what is tested
As the comparator · 2 — what is tested is compared with oxybate
- Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress DisorderCompletedNot applicablePsychiatric University Hospital, ZurichNCT04508166Written as Gamma-Hydroxybutyrate
- A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and PharmacodynamicsCompletedPhase 1Concert PharmaceuticalsNCT02215499Written as Sodium Oxybate
Codes
What other systems call oxybate · ClinicalTrials.gg INT004059
- UNII (FDA) 30IW36W5B2OXYBATEConfirmed FDA, NLM
- RxNorm 2387302One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | 30IW36W5B2 | OXYBATE | Confirmed FDA, NLM |
| RxNorm | 2387302 | — | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.