Nervous System Diseases clinical trials
The registry lists 757 studies for Nervous System Diseases across more than 10 countries. 218 are recruiting or about to start. 151 of them are mainly about Nervous System Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 505 narrower conditions too, such as Pain: 98,639 studies, 22,136 open.
ClinicalTrials.gov finds 84,555 studies for Nervous System Diseases. How that becomes 757 here
This page counts the studies the registry files under Nervous System Diseases, and those it files under no condition that list Nervous System Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 84,555Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −78,766Filed under a narrower condition, counted on its own pageStroke 7,718 · Parkinson Disease 4,348 · Pain 4,118 · Alzheimer Disease 3,661 · Multiple Sclerosis 2,926 · Sleep Initiation and Maintenance Disorders 2,465 · 464 more
- −40List Nervous System Diseases as a condition, but the registry did not file them under itMost often written as “Functional Neurological Disorder” (21), “Intensive Care Neurological Disorder” (4), and “Autonomic Nervous System Disease” (2). The registry filed 7 of them under no condition at all, and the others under other conditions only, most often Conversion Disorder (23) and Hypertension (1).
- −4,992Match it another way18 name it in the title, 7 in a keyword, and 4,967 by a synonym or other text the search reads.
- 757The count on this page
Get an email when these change. Save the Nervous System Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (16) · Otsuka Pharmaceutical Development & Commercialization, Inc. (7) · VA Office of Research and Development (7) · Assistance Publique - Hôpitaux de Paris (7) · National Institute of Mental Health (NIMH) (6) · Eli Lilly and Company (5) · BDH-Klinik Hessisch Oldendorf (5) · IRCCS Centro Neurolesi Bonino Pulejo (5)
What is being tested here
Drugs under test in Nervous System Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| ML-007C | 3 | 0 | 4 |
| Immunoglobulin G | 2 | 2 | 3 |
| Immunoglobulins, Intravenous | 2 | 1 | 2 |
| Testosterone | 2 | 1 | 2 |
| Islet Amyloid Polypeptide | 2 | 0 | 2 |
| Tenecteplase | 1 | 1 | 3 |
| Dexmedetomidine | 1 | 2 | 3 |
| Donanemab | 1 | 1 | 2 |
| Rituximab | 1 | 1 | 2 |
| Finasteride | 1 | 1 | 2 |
Drug classes tested here Dopamine agonists 6 · SSRIs 4 · Cholinesterase inhibitors 4 · Antipsychotics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS · Phase 3 · Amsterdam UMC, location VUmc
- Jul 2027A Phase 3 Study of NTLA-2001 in ATTRv-PN · Phase 3 · Intellia Therapeutics
- Sep 2027A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence · Phase 3 · Centessa Pharmaceuticals (UK) Limited
- Nov 2026Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder · Natalia Poluektova
- Nov 2026Advanced Multisensorial System for Automatic Assessment of Neurological Disorders in Smart Spaces-Universidad Rey Juan Carlos (URJC) · Universidad Rey Juan Carlos
- Dec 2026Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends · Axogen Corporation
- Dec 2026Modafinil and Cognitive Function in POTS · Vanderbilt University Medical Center
- Dec 2026A Muscle-brain Interplay Study in Neurological Disorders · Istituti Clinici Scientifici Maugeri SpA
- Dec 2026Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Dec 2026Multimodal CT Examination in Stroke Mimics Diagnosis · University Hospital Ostrava
Who these studies take
Of the 159 Nervous System Diseases studies recruiting now, 78 (49%) set no upper age limit and 44 (28%) stop at 75 or younger. 46 (29%) take children under 18. 1 (1%) are for women only and 2 (1%) for men only; 43 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 38 (24%) | 39 (25%) |
| 18 | 120 (75%) | 120 (75%) |
| 30 | 119 (75%) | 119 (75%) |
| 40 | 121 (76%) | 121 (76%) |
| 50 | 127 (80%) | 127 (80%) |
| 65 | 137 (86%) | 137 (86%) |
| 75 | 126 (79%) | 126 (79%) |
| 85 | 105 (66%) | 106 (67%) |
Across all 757 studies, recruiting or not: 32% stop at 75 or younger and 22% at 65; 23% take children; 1% are for women only and 3% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nervous System Diseases studies take
Of 49 phase 2 interventional studies under Nervous System Diseases, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 31 mo11–45 · 17 studies | — | — |
| Phase 2 | 28 mo15–53 · 49 studies | — | — |
| Phase 3 | 42 mo28–55 · 40 studies | 44 mo28–56 · 36 studies | — |
| Interventional, no phase | 30 mo11–57 · 193 studies | — | 28 mo11–57 · 167 studies |
| Observational | 53 mo20–121 · 114 studies | — | 55 mo19–150 · 97 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- Functional Outcomes and Control Using Synchron BCI - CanadaTerminatedNov 6, 2026NCT07446114
Newly registered5
- Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)Nov 3, 2026NCT07912320
- Advanced Multisensorial System for Automatic Assessment of Neurological Disorders in Smart Spaces-Universidad Rey Juan Carlos (URJC)Nov 2, 2026NCT07909824
- Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System DisordersOct 28, 2026NCT07900672
- Effects and Feasibility of a HABIT-ILE and a Home Program on the Bimanual Performance of Children With Cerebral PalsyOct 22, 2026NCT07889622
- Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral PalsyOct 15, 2026NCT07876219
Studies
Recruiting first, then most recently updated. Showing 50 of 757. Browse all 757 → or search them.
- A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic TherapyRecruitingNCT07804615Phase 22 countries
- Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT000605411 country
- A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 SkippingRecruitingNCT07587242Phase 310 countries
- Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases.RecruitingNCT048803561 country
- Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal MetastasesRecruitingNCT07098806Phase 1/21 country
- Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)RecruitingNCT068056953 countries
- A Muscle-brain Interplay Study in Neurological DisordersRecruitingNCT074778211 country
- Advanced Multisensorial System for Automatic Assessment of Neurological Disorders in Smart Spaces-Universidad Rey Juan Carlos (URJC)Not yet recruitingNCT079098241 country
- A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)RecruitingNCT07589595Phase 24 countries
- The Mechatronic Remote Physiotherapy System (MRPS) in Remote Stroke RehabilitationNot yet recruitingNCT06964789Not applicable
- A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of HypersomnolenceRecruitingNCT07598708Phase 2/31 country
- Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)Enrolling by invitationNCT07912320Not applicable1 country
- Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked PotentialsEnrolling by invitationNCT069637751 country
- A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's DiseaseRecruitingNCT06297590Phase 13 countries
- Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System DisordersRecruitingNCT079006721 country
- Mindfulness-based Lifestyle Modification Programme for Caregivers of People With Neurological DisordersRecruitingNCT07342140Not applicable1 country
- A Study Investigating Intravenous Human Normal Immune Globulin 10% in Adults With Stiff Person SyndromeNot yet recruitingNCT07552987Phase 3
- Product Surveillance RegistryRecruitingNCT0152427641 countries
- An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter DiseaseRecruitingNCT05757141Phase 1/23 countries
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- Market Research of a Slow Release Protein Substitute for the Dietary Management of PKUNot yet recruitingNCT07802366Not applicable1 country
- A Long-Term Open-Label Study of ML-007C-MA in Adults With SchizophreniaRecruitingNCT07459647Phase 21 country
- Feasibility Trial of Family-Centered Therapeutic Dance for Children With DisabilitiesRecruitingNCT07166055Not applicable1 country
- Slow-SPEED: Slowing Parkinson's Early Through Exercise DosageRecruitingNCT06993142Not applicable2 countries
- Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral PalsyNot yet recruitingNCT07876219Not applicable1 country
- A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type IEnrolling by invitationNCT06926621Phase 28 countries
- Ear-Seizure Detection (EarSD) StudyRecruitingNCT06598189Not applicable1 country
- Advanced Space-time Resolved Techniques for Functional Neuroimaging at 7 Tesla MRIRecruitingNCT07865546Not applicable1 country
- NightWare and Cardiovascular Health in Veterans With PTSDRecruitingNCT06419959Not applicable1 country
- Managed Access Program for Del-zota in Participants With DMD Mutations Amenable to Exon 44 SkippingAvailableNCT072507371 country
- Pediatric EpilepsyRecruitingNCT07350551Not applicable1 country
- Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and PathologyRecruitingNCT062036261 country
- A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)RecruitingNCT07704840Phase 21 country
- Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid HemorrhageRecruitingNCT044496661 country
- Prognostic Factors to Regain ConsciousnessRecruitingNCT044456491 country
- A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease PsychosisRecruitingNCT06887192Phase 215 countries
- Video Call Assisted Assessment of Acute StrokeRecruitingNCT06570681Not applicable1 country
- The Neurodevelopmental and Behavioral Phenotyping Screening ProtocolRecruitingNCT002716221 country
- Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their FamiliesRecruitingNCT05744310Not applicable1 country
- Digital Patient Engagement in Technology-Supported NeurorehabilitationNot yet recruitingNCT077940721 country
- The EXOPULSE Study - a Database for Routine Follow-up of Clinical OutcomesRecruitingNCT059012591 country
- Natural History of Type 1 Interferonopathies: Insights From a European CohortRecruitingNCT0704077411 countries
- Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving SimulatorNot yet recruitingNCT07809828
- Longitudinal Assessment of Protein Markers in the Cerebrospinal Fluid of Patients With Central Nervous System InvolvementNot yet recruitingNCT073130981 country
- HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 11 country
- PRophylaxis Against Early VENTilator-associated Infections in Acute Brain InjuryRecruitingNCT06819592Phase 33 countries
- Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-NetherlandsRecruitingNCT06193252Not applicable1 country
- Top-Down Attentional Control of Visual-ProcessingRecruitingNCT010872811 country
- Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's DiseaseRecruitingNCT05926011Not applicable1 country
- PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute StrokeRecruitingNCT061213361 country