Drug
Trazodone clinical trials
Also written Desyrel and Trittico®.
- studies test it
- 50
- open now
- 12
- in phase 3
- 10
- first study started
- 2000
Keep track of what changes. Save the Trazodone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
49 studies that test it; most in 2017 (5); 1 more planned to start later
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2002 | 1 |
| 2005 | 2 |
| 2007 | 1 |
| 2008 | 4 |
| 2009 | 1 |
| 2010 | 2 |
| 2011 | 4 |
| 2012 | 3 |
| 2013 | 1 |
| 2015 | 3 |
| 2017 | 5 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 2 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 4 |
| 2025 | 2 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 12
- Phase 2
- 11
- Phase 3
- 10
- Phase 4
- 13
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 12 · Other 38
Labopharm Inc. (5) · Aziende Chimiche Riunite Angelini Francesco S.p.A (4) · Brigham and Women's Hospital (4) · VA Office of Research and Development (3) · University of Washington (2) · Milton S. Hershey Medical Center (2) · Lee's Pharmaceutical Limited (2) · Centre hospitalier de l'Université de Montréal (CHUM) (2)
Often tested with
Tested in the same studies.
Zolpidem (4) · Quetiapine (4) · Diphenhydramine (3) · Eszopiclone (2) · Fluoxetine (2) · Fluvoxamine (2) · Paroxetine (2) · Sertraline (2)
Studies
Open first, then newest update. How each study uses Trazodone is read from its arms, and is right about nine times in ten.
Testing it · 50
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingPhase 4VA Office of Research and DevelopmentNCT07210606Written as Trazodone + positive airway pressure (PAP) therapy
- Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)RecruitingPhase 2Centre Hospitalier St AnneNCT07210112Written as Trazodone 5mg
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingPhase 4University of PennsylvaniaNCT07542756Written as Trazodone, 50 mg
- Rescue Pharmacotherapy for OSARecruitingPhase 1/2Brigham and Women's HospitalNCT05293600Written as Trazodone
- Treatment of Sleep Apnea in Patients With Cervical Spinal Cord InjuryRecruitingPhase 4John D. Dingell VA Medical CenterNCT02922894Written as Trazodone
- Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With TrazodoneRecruitingPhase 2Johns Hopkins UniversityNCT05282550Written as Trazodone
- Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia SymptomsRecruitingPhase 4Brigham and Women's HospitalNCT07136415Written as Trazodone
- Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised TrialRecruitingPhase 2/3University of EdinburghNCT04302870Written as Trazodone Hydrochloride oral solution
- Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)RecruitingPhase 2Centre hospitalier de l'Université de Montréal (CHUM)NCT06983080Written as Trazodone 25 mg
- Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in InsomniaRecruitingEarly Phase 1Milton S. Hershey Medical CenterNCT06281756Written as Trazodone
- Trazodone on OSA EndotypesRecruitingPhase 1/2Brigham and Women's HospitalNCT06286189Written as Trazodone Hydrochloride
- Quetiapine Versus Trazadone in Women With Postpartum DepressionNot yet recruitingEarly Phase 1London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNCT06546358Written as Trazodone
- National Adaptive Trial for PTSD Related InsomniaCompletedPhase 3VA Office of Research and DevelopmentNCT03668041Written as Trazodone
- RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ)WithdrawnPhase 4University of Southern CaliforniaNCT05085808Written as Trazodone
- Evaluation of Trazodone in OSA-MCIActive, not recruitingPhase 4Chinese University of Hong KongNCT05209035Written as Trazodone
- Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state.CompletedPhase 1Aziende Chimiche Riunite Angelini Francesco S.p.ANCT06773767Written as 150 mg trazodone hydrochloride
- Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of TrazodoneWithdrawnPhase 1Verinder SharmaNCT05299398Written as Trazodone
- CBT-I or Zolpidem/Trazodone for InsomniaCompletedPhase 4California Pacific Medical Center Research InstituteNCT04468776Written as Trazodone
- Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing HemodialysisCompletedPhase 3University of WashingtonNCT03534284Written as Trazodone
- Memory Enhancement by Gamma-hydroxybutyrate vs. Trazodone in Major Depressive Disorder.CompletedPhase 2Erich SeifritzNCT04082806Written as Trazodone
See all 50 studies that test Trazodone →
Given in every arm · 1 — Trazodone is usual care beside what is tested
As the comparator · 3 — what is tested is compared with Trazodone
- Investigating the Effectiveness of E-CBTi Compared to Pharmaceutical Interventions in Treating InsomniaRecruitingNot applicableDr. Nazanin AlaviNCT05125146Written as Trazodone
- Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting ConditionsCompletedPhase 1Aziende Chimiche Riunite Angelini Francesco S.p.ANCT05136521Written as Trazodone HCl - Contramid®
- Algorithm Guided Treatment Strategies for Major Depressive DisorderStatus unknownPhase 4Shanghai Mental Health CenterNCT01764867Written as Trazodone
Codes
What other systems call Trazodone · ClinicalTrials.gg INT008344
- MeSH (NLM) D014196TrazodoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) YBK48BXK30TRAZODONEConfirmed FDA, NLM, Wikidata
- RxNorm 10737Confirmed FDA, Wikidata
- Wikidata Q411457trazodoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29510TrazodoneOne source FDA
- DrugBank DB00656One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014196 | Trazodone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | YBK48BXK30 | TRAZODONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10737 | — | Confirmed FDA, Wikidata |
| Wikidata | Q411457 | trazodone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29510 | Trazodone | One source FDA |
| DrugBank | DB00656 | — | One source Wikidata |
Also registered as trazodone hydrochloride (UNII 6E8ZO8LRNM · RxNorm 82112).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.