Mental Disorders clinical trials
The registry lists 1,740 studies for Mental Disorders across more than 10 countries. 348 are recruiting or about to start. 702 of them are mainly about Mental Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 176 narrower conditions too, such as Anxiety Disorders: 52,216 studies, 11,307 open.
ClinicalTrials.gov finds 51,019 studies for Mental Disorders. How that becomes 1,740 here
This page counts the studies the registry files under Mental Disorders, and those it files under no condition that list Mental Disordersthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 51,019Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −44,917Filed under a narrower condition, counted on its own pageAnxiety Disorders 7,042 · Alzheimer Disease 3,751 · Schizophrenia 3,152 · Cognitive Dysfunction 2,856 · Sleep Initiation and Maintenance Disorders 2,337 · Stress Disorders, Post-Traumatic 2,115 · 149 more
- −76List Mental Disorders as a condition, but the registry did not file them under itMost often written as “Serious Mental Illness” (15), “Mental Disorder in Adolescence” (8), and “Stigma of Mental Illness” (7). The registry filed 46 of them under no condition at all, and the others under other conditions only, most often Social Stigma (7) and Psychological Well-Being (7).
- −4,286Match it another way97 name it in the title, 17 in a keyword, and 4,172 by a synonym or other text the search reads.
- 1,740The count on this page
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Status
Who runs them
VA Office of Research and Development (35) · National Center for Research Resources (NCRR) (28) · Otsuka Pharmaceutical Development & Commercialization, Inc. (25) · Centre for Addiction and Mental Health (20) · Yale University (19) · Charite University, Berlin, Germany (18) · National Institute of Mental Health (NIMH) (18) · King's College London (16)
What is being tested here
Drugs under test in Mental Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 3 | 0 | 6 |
| ML-007C | 3 | 0 | 4 |
| Ketamine | 2 | 1 | 10 |
| Semaglutide | 2 | 0 | 3 |
| Melatonin | 2 | 1 | 3 |
| Esketamine | 2 | 0 | 2 |
| Risperidone | 1 | 4 | 7 |
| Omega-3 fatty acid | 1 | 2 | 6 |
| Oxytocin | 1 | 0 | 4 |
| Quetiapine | 1 | 2 | 4 |
Drug classes tested here Antipsychotics 2 open · GLP-1 receptor agonists 2 open · Stimulants 1 open · Opioids 1 open · SSRIs 13
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms. · Phase 3 · Louisiana State University Health Sciences Center Shreveport
- Sep 2027A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence · Phase 3 · Centessa Pharmaceuticals (UK) Limited
- Nov 2026A Randomized Controlled Trial on Brief Behavioral Parent Training · Accare
- Nov 2026Effectiveness of the SKILLS Program in the Management of Psychiatric Disorders · University Hospital, Tours
- Nov 2026CBT-I to Improve Functional Outcomes in Veterans With Psychosis · VA Office of Research and Development
- Nov 2026Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness · Centre hospitalier de Ville-Evrard, France
- Dec 2026Assessment of Activity Limitations, a Basis for Understanding the Need for Sickness Certificate and Rehabilitation · Göteborg University
- Dec 2026Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness · Biruni University
- Dec 2026The Green Room: Virtual Nature for Mental Well-being in the Acute Psychiatry Ward · Hospital Clinic of Barcelona
- Dec 2026Evaluation of a Digital Pre-therapy Patient Education Program (StartHjelp) in Outpatient Mental Health Care · St. Olavs Hospital
Who these studies take
Of the 243 Mental Disorders studies recruiting now, 104 (43%) set no upper age limit and 112 (46%) stop at 75 or younger. 61 (25%) take children under 18. 14 (6%) are for women only and 1 (<1%) for men only; 70 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 32 (13%) | 32 (13%) |
| 18 | 193 (79%) | 180 (74%) |
| 30 | 189 (78%) | 176 (72%) |
| 40 | 183 (75%) | 171 (70%) |
| 50 | 179 (74%) | 171 (70%) |
| 65 | 178 (73%) | 171 (70%) |
| 75 | 137 (56%) | 131 (54%) |
| 85 | 120 (49%) | 114 (47%) |
Across all 1,740 studies, recruiting or not: 48% stop at 75 or younger and 43% at 65; 28% take children; 4% are for women only and 2% for men only; 28% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Mental Disorders studies take
Of 56 phase 2 interventional studies under Mental Disorders, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 12 mo1–43 · 27 studies | — | — |
| Phase 2 | 24 mo17–35 · 56 studies | 22 mo12–25 · 28 studies | — |
| Phase 3 | 34 mo19–59 · 28 studies | — | — |
| Phase 4 | 31 mo16–84 · 17 studies | — | — |
| Interventional, no phase | 29 mo13–45 · 680 studies | — | 29 mo13–45 · 666 studies |
| Observational | 37 mo13–77 · 156 studies | — | 37 mo12–77 · 149 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Understanding and Targeting Self-Regulatory Control in Bulimia NervosaNov 5, 2026NCT07581158
- Facilitation to Increase Tobacco TreatmentOct 15, 2026NCT07455526
Results posted1
Newly registered13
- Concomitant Fibromyalgia and Psychiatric DisordersNov 6, 2026NCT07920913
- Antipsychotic Safety and Adherence in Patients With Psychiatric Disorders-An Egyptian Institution-Based Cross-Sectional Study.Nov 3, 2026NCT07914192
- Future School of Comprehensive Well-BeingOct 30, 2026NCT07906522
- Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital BiomarkersOct 29, 2026NCT07905378
- Community-Based Intensive Treatment (CBIT): Meeting the Complex Needs of Rural Adults With Serious Mental IllnessOct 21, 2026NCT07887113
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- Hybrid Pilot of Personalized Parent-Child Interaction TherapyOct 21, 2026NCT07887295
- Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 YearsOct 19, 2026NCT07880717
- Supporting Older Adults RemotelyOct 16, 2026NCT07878169
- Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental IllnessOct 16, 2026NCT07879118
- A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental IllnessOct 16, 2026NCT07879131
- Effects of Nurse-Led School-Based Mental Health Education on Beliefs Toward Mental Illness, Social Distance, and Empathy in AdolescentsOct 16, 2026NCT07879352
- LLM Psychiatric Intake AI Clinical Performance StudyOct 15, 2026NCT07875816
- A Digital Mindfulness-Based Program for OCDOct 13, 2026NCT07871344
Studies
Recruiting first, then most recently updated. Showing 50 of 1,740. Browse all 1,740 → or search them.
- Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare WorkersRecruitingNCT06977503Not applicable1 country
- Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric AnxietyRecruitingNCT06595953Phase 21 country
- Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and MuscleRecruitingNCT01266577Not applicable1 country
- HNC: Human Neural Circuits Electrophysiology During CognitionRecruitingNCT05962424Phase 11 country
- Understanding and Targeting Self-Regulatory Control in Bulimia NervosaRecruitingNCT07581158Not applicable1 country
- Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)RecruitingNCT06914622Not applicable1 country
- Antipsychotic Safety and Adherence in Patients With Psychiatric Disorders-An Egyptian Institution-Based Cross-Sectional Study.Not yet recruitingNCT07914192
- A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of HypersomnolenceRecruitingNCT07598708Phase 2/31 country
- QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)Not yet recruitingNCT07661823Not applicable1 country
- A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's DiseaseRecruitingNCT06297590Phase 13 countries
- Recovering Sleep After TraumaRecruitingNCT07196332Not applicable1 country
- Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital BiomarkersNot yet recruitingNCT07905378
- Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in AdolescentsRecruitingNCT06433583Not applicable1 country
- Community-Based Intensive Treatment (CBIT): Meeting the Complex Needs of Rural Adults With Serious Mental IllnessNot yet recruitingNCT078871131 country
- A Brief Case Management Intervention to Promote Personal Recovery and Prevent Psychiatric Involuntary Readmissions.RecruitingNCT07497763Not applicable1 country
- Supporting Older Adults RemotelyNot yet recruitingNCT07878169Not applicable1 country
- Hybrid Pilot of Personalized Parent-Child Interaction TherapyNot yet recruitingNCT07887295Not applicable1 country
- Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 YearsRecruitingNCT078807171 country
- Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in ParticipantsRecruitingNCT07216534Not applicable1 country
- Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental IllnessNot yet recruitingNCT07879118Not applicable1 country
- A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental IllnessNot yet recruitingNCT07879131Not applicable1 country
- Successful Transitions and Reintegration Tools for Veterans (START-VETS)RecruitingNCT04366531Not applicable1 country
- A Long-Term Open-Label Study of ML-007C-MA in Adults With SchizophreniaRecruitingNCT07459647Phase 21 country
- Facilitation to Increase Tobacco TreatmentRecruitingNCT07455526Not applicable1 country
- Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients With Opioid Use Disorder and Serious Mental IllnessNot yet recruitingNCT07865078Not applicable
- A Digital Mindfulness-Based Program for OCDNot yet recruitingNCT07871344Not applicable
- FMRI-neurofeedback in DepressionRecruitingNCT05640089Not applicable1 country
- Supporting Treatment Access and Recovery in CODRecruitingNCT05138614Not applicable1 country
- Use of AI Chatbots for Mental HealthEnrolling by invitationNCT076585471 country
- Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied RelaxationNot yet recruitingNCT07866794Not applicable1 country
- NightWare and Cardiovascular Health in Veterans With PTSDRecruitingNCT06419959Not applicable1 country
- Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri StudyRecruitingNCT06117163Not applicable1 country
- Medical Comorbidities in Bipolar DisorderRecruitingNCT068723981 country
- Psychosocial Factors in Dual Diagnosis in a General HospitalRecruitingNCT074430331 country
- Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionRecruitingNCT06511908Phase 21 country
- Employing Peer Outreach and Whole Health in Recovery for Homeless-Experienced VeteransNot yet recruitingNCT07309224Not applicable1 country
- Motivational Intervention for Patients With SchizophreniaNot yet recruitingNCT07853079Not applicable
- Efficacy of the I-CARE Digital Health InterventionRecruitingNCT07150832Not applicable1 country
- A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease PsychosisRecruitingNCT06887192Phase 215 countries
- SBIR/ STTR Family Check-up OnlineRecruitingNCT06876246Not applicable1 country
- Aerobic Exercise and Obsessive-Compulsive Disorder SymptomsRecruitingNCT07103902Not applicable1 country
- Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar DisordersNot yet recruitingNCT07845409Not applicable1 country
- TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric PatientsNot yet recruitingNCT078447981 country
- Safety and Efficacy of HB-1 for Post-Traumatic Stress DisorderRecruitingNCT07499440Phase 21 country
- Cognition and Affective Research in ChinaNot yet recruitingNCT078332671 country
- Engaging Mental Health Services for Preschoolers at RiskRecruitingNCT07054554Not applicable1 country
- Targeted Plasticity Therapy for PTSDRecruitingNCT06266364Not applicable1 country
- Trauma-Focused Group Therapy for Adults With Trauma-Related Symptoms in Primary CareRecruitingNCT07757334Not applicable1 country
- Effect Study of SMART Treatment for YouthRecruitingNCT07200713Not applicable1 country
- Mental Health Reinforcement in Wayapi and Teko Communities in French Guiana : Evaluation of the Impact of a Mediation Based Activity in Municipalities of Camopi and Trois Saut in French GuianaNot yet recruitingNCT078088011 country