VA Office of Research and Development clinical trials
Listed in the registry as: U.S. federal agency.
The registry lists 1,768 studies whose lead sponsor is VA Office of Research and Development. 393 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 26, 2026.
Keep track of what changes. Save the VA Office of Research and Development studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesStatus
Focus areas
Conditions VA Office of Research and Development leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Stress Disorders, Post-Traumatic223Depression81Spinal Cord Injuries74Stroke69Brain Injuries, Traumatic59Substance-Related Disorders56Chronic Pain52Schizophrenia48Alcoholism47Brain Injuries47Psychotic Disorders43Sleep Initiation and Maintenance Disorders43Cardiovascular Diseases42Parkinson Disease42Diabetes Mellitus39Mental Disorders39Obesity38Heart Failure36Sleep Apnea Syndromes36Depressive Disorder33Hypertension33Pulmonary Disease, Chronic Obstructive33Cognitive Dysfunction32Pain27
Show all 62 areas
Wounds and Injuries27Brain Concussion26Dementia24Sleep Apnea, Obstructive24Depressive Disorder, Major22Renal Insufficiency, Chronic22Bipolar Disorder21Prostatic Neoplasms21Osteoarthritis20Low Back Pain19Suicide Prevention19Apnea18Opioid-Related Disorders18Tobacco Use Disorder18Back Pain17Hearing Loss17Multiple Sclerosis17Suicidal Ideation17COVID-1916Kidney Diseases16Peripheral Arterial Disease16Aphasia15Diabetes Mellitus, Type 215Lung Neoplasms15Osteoarthritis, Knee15Alzheimer Disease14Musculoskeletal Pain13Colorectal Neoplasms11Coronary Artery Disease11Frailty11Hepatitis C11Overweight11Post-Acute COVID-19 Syndrome11Fatigue10Neoplasms10Prediabetic State10Sclerosis10Suicide, Attempted10
Studies
Recruiting first, then most recently updated. Showing 50 of 1,768. Browse all 1,768 →
- Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury ClinicRecruitingNCT06529094Not applicable
- A Neuroprosthesis for Seated Posture and BalanceRecruitingNCT01474148Not applicable
- A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN LossRecruitingNCT05593497Phase 2
- Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means CounselingNot yet recruitingNCT07033884Phase 1/2
- Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANTNot yet recruitingNCT07158567Phase 3
- Psilocybin for Depression in VeteransNot yet recruitingNCT07895134Phase 2
- Adjunctive Motivational Alcohol Intervention to Prevent IPVRecruitingNCT05287711Not applicable
- Veterans Affairs Lung Cancer Surgery Or Stereotactic RadiotherapyRecruitingNCT02984761Not applicable
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionRecruitingNCT07226232Phase 3
- I-SLEPT: Integrated Sleep and Life Engagement Program for TransitionsRecruitingNCT07317336Not applicable
- Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With ObesityRecruitingNCT06745063Phase 2
- Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older VeteransNot yet recruitingNCT06963970Not applicable
- Tocilizumab Combined With First-Line Chemo-Immunotherapy in Metastatic Non-Small Cell Lung CancerNot yet recruitingNCT07889232Phase 1/2
- Strengthening Neuro-Cognitive Skills for Success in School, Work and BeyondRecruitingNCT04109027Not applicable
- Veteran Peer Navigators to Promote Shared Decision Making for PSA ScreeningNot yet recruitingNCT06549036Not applicable
- Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With GoutRecruitingNCT06887452Not applicable
- Sleep MAPP in the Polytrauma/TBI System of CareNot yet recruitingNCT07886398Not applicable
- Salience Network Informed rTMS for PTSDNot yet recruitingNCT07886840Phase 2
- Preventing Loss of Independence Through Exercise in Community Living CentersEnrolling by invitationNCT06972004Not applicable
- OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment UnitRecruitingNCT05156112Not applicable
- Basal Cell Carcinoma Chemoprevention TrialRecruitingNCT05212246Phase 3
- Allopregnanolone in Chronic Complex Traumatic Brain InjuryNot yet recruitingNCT04003285Phase 2
- Service and Health Among Deployed VeteransEnrolling by invitationNCT02825654
- Ca-Mg Butyrate in Gulf War IllnessRecruitingNCT05367245Phase 2
- hCG Treatment for Rehabilitation From a TBINot yet recruitingNCT07557615Early Phase 1
- Boosting Exercise Adherence in Knee OsteoarthritisNot yet recruitingNCT07219732Not applicable
- Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson DiseaseNot yet recruitingNCT07187466Phase 4
- Successful Transitions and Reintegration Tools for Veterans (START-VETS)RecruitingNCT04366531Not applicable
- AAT for Alcohol Use Disorder in VeteransRecruitingNCT05372029Not applicable
- VA Quality Enhancement Research Initiative (QUERI) CARRIAGE VASTEnrolling by invitationNCT07877662Not applicable
- Options for Pain Management Using Nonpharmacological StrategiesRecruitingNCT05563792Not applicable
- Facilitation to Increase Tobacco TreatmentRecruitingNCT07455526Not applicable
- Assessing Trauma-related Links Between Affective and Metabolic SystemsNot yet recruitingNCT07862712Phase 4
- A New Intervention to Improve Function in Veterans With Anxiety and DepressionRecruitingNCT06188923Phase 2
- EVOLV-Rx VA: Evaluating Opportunities to Decrease Low-Value Prescribing in Community Living CentersEnrolling by invitationNCT07166107Not applicable
- CSP #2026 - Beta Blocker Dialyzability on Cardiovascular OutcomesRecruitingNCT05931276Phase 3
- Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual ViolenceRecruitingNCT06746740Not applicable
- Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)RecruitingNCT04867317Phase 3
- Sensory Synchronized Imaging and NeuromodulationNot yet recruitingNCT06548113Not applicable
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingNCT07210606Phase 4
- Rapid Personalization of Safety Plans for Psychiatrically Hospitalized Veterans at High-Risk for SuicideNot yet recruitingNCT07507786Not applicable
- Algorithm-enabled Goals of Care CommunicationEnrolling by invitationNCT07690904Not applicable
- A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal CancerRecruitingNCT05563766Phase 2
- Cognitive Control Training for Extinction in PTSDRecruitingNCT06629064Not applicable
- Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among VeteransNot yet recruitingNCT07104318Phase 3
- Implementing a Mobile Health Application for Women Veterans With Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0RecruitingNCT07219433Not applicable
- NightWare and Cardiovascular Health in Veterans With PTSDRecruitingNCT06419959Not applicable
- Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery TrajectoriesRecruitingNCT05288803
- EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following StrokeRecruitingNCT05628324Not applicable
- Combining a Smartphone App With Medications to Manage Heavy DrinkingRecruitingNCT06303778Not applicable