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Sleep Disorders, Circadian Rhythm clinical trials

The registry lists 135 studies for Sleep Disorders, Circadian Rhythm across more than 10 countries. 25 are recruiting or about to start. 76 of them are mainly about Sleep Disorders, Circadian Rhythm (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.

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Status

Completed
82
Recruiting
14
Status unknown
13
Not yet recruiting
9
Terminated
8
Active, not recruiting
5

Phase

Phase 3
15
Phase 4
8
Phase 2
8
Phase 1
6
Early Phase 1
1

Where

United States
69
Norway
7
Germany
5
Turkey
5
Denmark
4
Austria
3

Who runs them

Brigham and Women's Hospital (12) · Vanda Pharmaceuticals (9) · University of Bergen (4) · Federal University of Uberlandia (3) · Chinese University of Hong Kong (3) · University of California, San Francisco (3) · Cephalon (3) · Stanford University (3)

What is being tested here

Drugs under test in Sleep Disorders, Circadian Rhythm studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Melatonin3211
Tasimelteon169
Lemborexant102
Propofol101
Solriamfetol111
Tumor Necrosis Factor Ligand Superfamily Member 14101
Citalopram101
Modafinil022
Ramelteon002
Suvorexant001

Coming up

3phase 3 studies under way
10studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 10, phase 3 first

Who these studies take

Of the 14 Sleep Disorders, Circadian Rhythm studies recruiting now, 7 (50%) set no upper age limit and 4 (29%) stop at 75 or younger. 2 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (29%) take healthy volunteers.

Recruiting studies that take each age, of 14
AgeWomenMen
100 (0%)0 (0%)
1814 (100%)14 (100%)
3014 (100%)14 (100%)
4014 (100%)14 (100%)
5013 (93%)13 (93%)
6512 (86%)12 (86%)
7511 (79%)11 (79%)
858 (57%)8 (57%)

Across all 135 studies, recruiting or not: 57% stop at 75 or younger and 49% at 65; 19% take children; 4% are for women only and 3% for men only; 53% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Sleep Disorders, Circadian Rhythm studies take

Of 42 interventional studies with no phase under Sleep Disorders, Circadian Rhythm, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase28 mo8–46 · 42 studies—28 mo8–51 · 39 studies
Observational23 mo10–27 · 11 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting1

Studies

Recruiting first, then most recently updated. Showing 50 of 135. Browse all 135 → or search them.