Sleep Apnea, Obstructive clinical trials
The registry lists 2,240 studies for Sleep Apnea, Obstructive across more than 10 countries. 475 are recruiting or about to start. 1,799 of them are mainly about Sleep Apnea, Obstructive (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Obesity Hypoventilation Syndrome too: 2,301 studies, 482 open.
ClinicalTrials.gov finds 2,589 studies for Sleep Apnea, Obstructive. How that becomes 2,238 here
This page counts the studies the registry files under Sleep Apnea, Obstructive, and those it files under no condition that list Sleep Apnea, Obstructivethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,589Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −61Filed under a narrower condition, counted on its own pageObesity Hypoventilation Syndrome 61
- −41List Sleep Apnea, Obstructive as a condition, but the registry did not file them under itMost often written as “Obstructive Sleep Apnea of Adult” (10), “Obstructive Sleep Apnea of Child” (7), and “Obstructive Sleep Apnea-hypopnea Syndrome” (5). The registry filed them under other conditions only, most often Sleep Apnea Syndromes (15) and Apnea (4).
- −249Match it another way211 name it in the title, 4 in a keyword, and 34 by a synonym or other text the search reads.
- 2,238The count on this page70 of them list Sleep Apnea, Obstructive in their own words; the registry filed them under no condition.
Get an email when these change. Save the Sleep Apnea, Obstructive studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Fisher and Paykel Healthcare (63) · ResMed (50) · University Hospital, Grenoble (48) · Brigham and Women's Hospital (42) · University of California, San Diego (30) · Chinese University of Hong Kong (26) · VA Office of Research and Development (24) · University of Michigan (21)
What is being tested here
Drugs under test in Sleep Apnea, Obstructive studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Eszopiclone | 4 | 1 | 11 |
| Acetazolamide | 3 | 0 | 14 |
| Atomoxetine | 3 | 0 | 6 |
| Oxygen | 3 | 0 | 5 |
| Dronabinol | 3 | 1 | 4 |
| Trazodone | 2 | 0 | 5 |
| Lemborexant | 2 | 0 | 5 |
| UBT251 | 2 | 2 | 2 |
| HDM1005 | 2 | 2 | 2 |
| Bofanglutide | 2 | 2 | 2 |
Drug classes tested here Diuretics 3 open · Antimuscarinics 2 open · GLP-1 receptor agonists 2 open · Corticosteroids 12 · Stimulants 11
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity · Phase 3 · Fujian Shengdi Pharmaceutical Co., Ltd.
- Aug 2027Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy · Phase 3 · Amgen
- Aug 2027Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy · Phase 3 · Amgen
- Nov 2027Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy · Phase 3 · Gan & Lee Pharmaceuticals.
- Nov 2026The Effect of Continuous Positive Airway Therapy on the Blood Pressure in Sleepy vs Non-sleepy Patients With Obstructive Sleep Apnea · King's College London
- Nov 2026Level 3 Validation Study · Windsor Sleep Disorders Clinic
- Nov 2026CPAP in Patients With Severe Obesity After Anesthesia · Massachusetts General Hospital
- Nov 2026Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
- Nov 2026Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study · Tulane University
- Nov 2026Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal · University Hospital, Angers
Who these studies take
Of the 313 Sleep Apnea, Obstructive studies recruiting now, 145 (46%) set no upper age limit and 125 (40%) stop at 75 or younger. 53 (17%) take children under 18. 3 (1%) are for women only and 1 (<1%) for men only; 65 (21%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 47 (15%) | 46 (15%) |
| 18 | 227 (73%) | 225 (72%) |
| 30 | 254 (81%) | 251 (80%) |
| 40 | 262 (84%) | 260 (83%) |
| 50 | 262 (84%) | 261 (83%) |
| 65 | 253 (81%) | 251 (80%) |
| 75 | 206 (66%) | 204 (65%) |
| 85 | 163 (52%) | 161 (51%) |
Across all 2,240 studies, recruiting or not: 41% stop at 75 or younger and 26% at 65; 13% take children; 2% are for women only and 3% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Sleep Apnea, Obstructive studies take
Of 47 phase 2 interventional studies under Sleep Apnea, Obstructive, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 10 mo5–44 · 27 studies | — | — |
| Phase 2 | 26 mo9–46 · 47 studies | — | — |
| Phase 3 | 20 mo17–32 · 25 studies | — | — |
| Phase 4 | 26 mo17–35 · 31 studies | — | 26 mo18–35 · 28 studies |
| Interventional, no phase | 27 mo12–50 · 623 studies | 12 mo3–21 · 115 studies | 33 mo17–53 · 508 studies |
| Observational | 28 mo14–63 · 294 studies | 18 mo7–93 · 36 studies | 31 mo16–61 · 258 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting6
- A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)Nov 6, 2026NCT07881757
- A Study of the Sleepnet Elara APAP DeviceOct 27, 2026NCT07559708
- Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep ApneaOct 27, 2026NCT07889154
- Myofunctional Therapy for Children With OSAOct 21, 2026NCT07249944
- Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)Oct 15, 2026NCT07521319
Show 1 moreShow fewer
- Evaluation of the F&P Mask, US, 2026Oct 13, 2026NCT07826429
Results posted1
- Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)Nov 3, 2026NCT05811247
Newly registered21
- HALOA: Cardiac Coherence With CPAP for Obstructive Sleep ApneaNov 10, 2026NCT07929064
- The Impact of Myofunctional Therapy on Children With Sleep Apnea and ObesityNov 9, 2026NCT07925294
- Nightly Wearable Monitoring During Home-Based Submental Electrical Stimulation for Obstructive Sleep ApneaNov 6, 2026NCT07921329
- Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.Nov 6, 2026NCT07923760
- Development and Validation of a Multimodal Deep Learning Model Using Peripheral Oxygen Saturation and Ballistocardiography Signals for Predicting Apnea-Hypopnea Index in Obstructive Sleep ApneaNov 6, 2026NCT07923825
Show 16 moreShow fewer
- Functional Capacity in Obstructive Sleep ApneaNov 3, 2026NCT07913139
- Heart and Brain Blood Flow in Obstructive Sleep ApneaNov 3, 2026NCT07913269
- Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO)Nov 2, 2026NCT07910461
- Development and Clinical Validation of Artificial Intelligence Algorithms for Sleep Staging and Obstructive Sleep Apnea Screening Based on a Large-Scale Model Trained on Multimodal Physiological Signals From Diverse PopulationsOct 30, 2026NCT07908160
- Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude RegionsOct 29, 2026NCT07904260
- EEG Markers From Polysomnography and Cognitive Performance in Obstructive Sleep ApneaOct 27, 2026NCT07897474
- Testing Settings of NovaResp's cMAP® Software During Home PAP TherapyOct 27, 2026NCT07898254
- Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea With Complete Concentric CollapseOct 27, 2026NCT07898618
- Complementary Exercise-Based Therapy for Obstructive Sleep ApneaOct 23, 2026NCT07891247
- Effect of Transcutaneous Electrical Stimulation on Polysomnographic Parameters in Patients With Obstructive Sleep ApneaOct 23, 2026NCT07891702
- Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep ApneaOct 22, 2026NCT07889154
- Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort StudyOct 21, 2026NCT07886632
- Impact of Continuous Positive Airway Pressure Therapy on Bilateral Local Hippocampal Gray Matter Volume in Elderly Patients With Obstructive Sleep Apnea - Study BBBSASOct 20, 2026NCT07882433
- Effects of Surgery on Oral Frailty and Dysphagia in Patients With Obstructive Sleep ApneaOct 19, 2026NCT07880067
- A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)Oct 19, 2026NCT07881757
- PMOS in OSA Pilot StudyOct 13, 2026NCT07871149
Studies
Recruiting first, then most recently updated. Showing 50 of 2,240. Browse all 2,240 → or search them.
- HALOA: Cardiac Coherence With CPAP for Obstructive Sleep ApneaNot yet recruitingNCT07929064Not applicable
- The Impact of Myofunctional Therapy on Children With Sleep Apnea and ObesityNot yet recruitingNCT07925294Not applicable
- A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)RecruitingNCT07881757Phase 31 country
- Nightly Wearable Monitoring During Home-Based Submental Electrical Stimulation for Obstructive Sleep ApneaRecruitingNCT07921329Not applicable1 country
- Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.Not yet recruitingNCT07923760Phase 21 country
- Development and Validation of a Multimodal Deep Learning Model Using Peripheral Oxygen Saturation and Ballistocardiography Signals for Predicting Apnea-Hypopnea Index in Obstructive Sleep ApneaRecruitingNCT079238251 country
- Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement ApplianceRecruitingNCT065763101 country
- Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep ApneaRecruitingNCT050522161 country
- DRonabinol Treatment of OSARecruitingNCT06477952Phase 1/21 country
- A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or OverweightRecruitingNCT07369011Phase 311 countries
- Development of a Multimodal Deep Learning Model for Pediatric PatientsRecruitingNCT078054861 country
- Prediction of Tongue Base Obstruction During SleepRecruitingNCT067920451 country
- Functional Capacity in Obstructive Sleep ApneaRecruitingNCT079131391 country
- UBT251 Injection Phase Ⅲ Study (OSA-NPAP)Not yet recruitingNCT07767942Phase 3
- Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO)Not yet recruitingNCT079104611 country
- Heart and Brain Blood Flow in Obstructive Sleep ApneaNot yet recruitingNCT079132691 country
- Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep ApnoeaNot yet recruitingNCT07846865Phase 2/31 country
- Association Between Metabolic Associated Fatty Liver Disease and Obstructive Sleep ApneaNot yet recruitingNCT07716995
- Development and Clinical Validation of Artificial Intelligence Algorithms for Sleep Staging and Obstructive Sleep Apnea Screening Based on a Large-Scale Model Trained on Multimodal Physiological Signals From Diverse PopulationsRecruitingNCT079081601 country
- Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude RegionsNot yet recruitingNCT07904260Not applicable1 country
- Myofunctional Therapy for Obstructive Sleep ApneaEnrolling by invitationNCT07301125Not applicable1 country
- Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea With Complete Concentric CollapseNot yet recruitingNCT07898618Not applicable1 country
- EEG Markers From Polysomnography and Cognitive Performance in Obstructive Sleep ApneaNot yet recruitingNCT07897474
- Testing Settings of NovaResp's cMAP® Software During Home PAP TherapyNot yet recruitingNCT07898254Not applicable1 country
- Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep ApneaRecruitingNCT07889154Not applicable1 country
- Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary HypertensionRecruitingNCT055952001 country
- The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults StudyRecruitingNCT05988385Not applicable1 country
- Effect of Transcutaneous Electrical Stimulation on Polysomnographic Parameters in Patients With Obstructive Sleep ApneaRecruitingNCT07891702Not applicable1 country
- Myofunctional Therapy for Children With OSARecruitingNCT07249944Not applicable1 country
- Microbiome and Metabolomics Profiling in Children With OSARecruitingNCT064529921 country
- Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort StudyNot yet recruitingNCT07886632
- Impact GLP-1 Agonists Following BariatricRecruitingNCT06132477Phase 41 country
- Impact of Continuous Positive Airway Pressure Therapy on Bilateral Local Hippocampal Gray Matter Volume in Elderly Patients With Obstructive Sleep Apnea - Study BBBSASNot yet recruitingNCT07882433Not applicable1 country
- Effects of Surgery on Oral Frailty and Dysphagia in Patients With Obstructive Sleep ApneaRecruitingNCT078800671 country
- OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment UnitRecruitingNCT05156112Not applicable1 country
- A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in AdultsRecruitingNCT07679282Phase 41 country
- Evaluation of the F&P Mask, US, 2026RecruitingNCT07826429Not applicable1 country
- Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)RecruitingNCT07521319Not applicable1 country
- Development and Investigation of the ApneaTheraPlayRecruitingNCT07214636Not applicable1 country
- PMOS in OSA Pilot StudyRecruitingNCT07871149Not applicable1 country
- DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.RecruitingNCT07635563Phase 21 country
- MASLD in Type 2 Diabetes in Primary Care - a Follow-up StudyEnrolling by invitationNCT073121361 country
- Evaluation of F&P Mask, US, 2026Not yet recruitingNCT07847814Not applicable1 country
- Application of the Patient-reported Longitudinal Assessment Tool for OSA (PLATO) Questionnaire in Oral Appliance Therapy for Obstructive Sleep ApneaRecruitingNCT077898341 country
- AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaRecruitingNCT07571109Phase 310 countries
- Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down SyndromeNot yet recruitingNCT07658053Not applicable1 country
- Study on the Management of COMISARecruitingNCT07743931Not applicable1 country
- Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation AblationRecruitingNCT07444372Not applicable1 country
- SUNOSI® (Solriamfetol) Pregnancy RegistryRecruitingNCT064134201 country
- Pediatric/Adolescent WatchPAT 400 Reliability Pilot StudyNot yet recruitingNCT07851402Not applicable1 country