Periodontitis clinical trials
The registry lists 1,627 studies for Periodontitis across more than 10 countries. 326 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 993
- Status unknown
- 214
- Recruiting
- 176
- Not yet recruiting
- 128
- Active, not recruiting
- 66
- Enrolling by invitation
- 22
Phase
- Phase 2
- 151
- Phase 4
- 110
- Phase 3
- 93
- Phase 1
- 56
- Early Phase 1
- 31
Where
- Turkey
- 168
- Egypt
- 165
- India
- 132
- Turkey (Türkiye)
- 114
- Italy
- 99
- United States
- 90
Who runs them
Cairo University (71) · Postgraduate Institute of Dental Sciences Rohtak (63) · Government Dental College and Research Institute, Bangalore (29) · Ain Shams University (26) · Marmara University (20) · Saglik Bilimleri Universitesi (19) · University of Sao Paulo (19) · University of Baghdad (18)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,627 — search for more.
- Photodynamic Therapy as an Adjunct in Periodontal TreatmentEnrolling by invitationNCT07633405Not applicable1 country
- Clinical Effectiveness of Oxygen-Releasing Oral Gel as an Adjunct to Scaling and Root Debridement in Patients With Severe Periodontal Pockets: A Randomized Clinical TrialNot yet recruitingNCT07840859Not applicable1 country
- Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B PeriodontitisNot yet recruitingNCT07840716Not applicable
- Air Polishing for Pain and Compliance in Supportive Periodontal TherapyNot yet recruitingNCT07837947Not applicable1 country
- Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal TreatmentRecruitingNCT07822269Not applicable1 country
- The Effect of Dexamethasone on Short Term Patient Response: IV vs Oral AdministrationNot yet recruitingNCT07832110Phase 1/21 country
- The Role Oral Microbiome in the Development and Progression of Aorta Aneurysm and Carotid AtherosclerosisEnrolling by invitationNCT078249211 country
- SMOKING AND GINGIVAL CREVICULAR FLUID MFN1 AND NLRP3 LEVELS IN PERIODONTAL HEALTH AND PERIODONTITISRecruitingNCT078267281 country
- Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)RecruitingNCT015686971 country
- Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic GraftsRecruitingNCT07146776Not applicable1 country
- Laser Assisted Open Flap DebridementNot yet recruitingNCT07807215Not applicable1 country
- Xylitol and the Prevention of Periodontal Disease and Preterm Birth TrialRecruitingNCT07424846Phase 2/31 country
- Integrated Diabetes and Oral Health Care in OmanNot yet recruitingNCT07809477Not applicable
- Alb-PRF as an Adjunct to Regenerative Periodontal SurgeryNot yet recruitingNCT07805317Not applicable1 country
- Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal TreatmentNot yet recruitingNCT07803484Phase 31 country
- A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)RecruitingNCT07397312Not applicable1 country
- Evaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-ImplantitisNot yet recruitingNCT077971271 country
- Alb-PRF as an Adjunct to Nonsurgical Periodontal TherapyNot yet recruitingNCT07794046Not applicable1 country
- Minimally Invasive Non-Surgical Periodontal Therapy Alone vs. Minimally Invasive Non-Surgical Periodontal Therapy With I-PRF With or Without Chlorhexidine on Stage III Periodontitis PatientsNot yet recruitingNCT07791238Phase 1/2
- Exploration of the Utility of Dental-dedicated MRI for DentistryRecruitingNCT069481621 country
- Boron Levels, Oxidative Stress, and Inflammation in PeriodontitisRecruitingNCT077753781 country
- Occlusal Force and Chewing After Periodontal TherapyNot yet recruitingNCT07772115Not applicable
- Flapless Periodontal Regeneration Using Hyaluronic Acid Versus Enamel Matrix DerivativeRecruitingNCT07339605Not applicable1 country
- Caffeine Intake and Periodontal Treatment OutcomesNot yet recruitingNCT07747545Not applicable1 country
- Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in SmokersRecruitingNCT07597213Not applicable1 country
- Morphological Characteristics of Mandibular Molar Furcation Involvement and Efficacy of Regenerative Surgical TreatmentRecruitingNCT07770256Not applicable1 country
- Efficacy of PRF and Xenograft in Treating Mandibular Molar Furcation InvolvementsRecruitingNCT07764029Not applicable1 country
- Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DMNot yet recruitingNCT07753317Not applicable
- Minimally Invasive Non-Surgical Periodontal TreatmentNot yet recruitingNCT07755644Not applicable1 country
- Periodontitis on Gingival Crevicular Fluid MetobolomicsRecruitingNCT077397321 country
- Impact of Non-surgical Periodontal Treatment on Targeted MetabolomicsRecruitingNCT07740447Not applicable1 country
- Maternal Periodontal Inflammation and Pregnancy Outcomes: Salivary and Amniotic BiomarkersNot yet recruitingNCT07699978
- Adjunctive Subgingival Pomegranate Peel Extract Gel for Stage II-III PeriodontitisRecruitingNCT07725393Not applicable1 country
- Association Between Periodontal Disease and Chronic Neck PainRecruitingNCT077114311 country
- Tinder Fungus as an Adjunct to Non-surgical Periodontal Therapy for PeriodontitisNot yet recruitingNCT07482878Not applicable1 country
- This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis PatientsRecruitingNCT07707063Phase 41 country
- Virgin Coconut Oil Versus Chlorhexidine Mouthwash in Non-Surgical Periodontal Therapy of Periodontitis Patients. A Randomized Controlled Clinical Trial With Biochemical Assessment.Not yet recruitingNCT07706387Not applicable1 country
- Salivary Apelin, Chemerin, Ghrelin, and Lipocalin-2 Levels in Diabetic Patients With PeriodontitisRecruitingNCT077033451 country
- Short Implants in Unitary Implant-supported Rehabilitations in the Posterior Maxilla and Mandible: 5 Years of Follow-upNot yet recruitingNCT076884081 country
- Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III PeriodontitisRecruitingNCT07673185Not applicable1 country
- Evaluation of Masticatory Performance in Patients With PeriodontitisNot yet recruitingNCT076654891 country
- Autologous Platelet Concentrate (APC) in Intrabony DefectsRecruitingNCT04254861Not applicable1 country
- Evaluation of the Impact of Periodontitis and Its Treatment on Swallowing Functions and Oral Quality of LifeNot yet recruitingNCT07651579Not applicable1 country
- PRF as Adjunct to Subgingival Instrumentation in Step 2 Periodontal TherapyRecruitingNCT07013682Not applicable1 country
- Influence of Re-evaluation Timing After Phase I Periodontal Therapy on Clinical and Periodontal Outcomes.Not yet recruitingNCT07678125Not applicable1 country
- Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention TargetsNot yet recruitingNCT07674888Not applicable1 country
- Sterify Gel as an Adjunct to Non-Surgical Periodontal Therapy in PeriodontitisNot yet recruitingNCT07672665
- Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE)RecruitingNCT075753471 country
- Effects of Adjunctive Synbiotic Supplementation to Non-Surgical Periodontal Therapy in Smokers With PeriodontitisNot yet recruitingNCT07672379Not applicable1 country
- Bone Substitutes and NIPSA in Intrabony Periodontal Defects: A Randomized Controlled TrialRecruitingNCT07671963Not applicable2 countries