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Periodontitis clinical trials

The registry lists 1,231 studies for Periodontitis across more than 10 countries. 295 are recruiting or about to start. 812 of them are mainly about Periodontitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Chronic Periodontitis: 1,907 studies, 404 open.

ClinicalTrials.gov finds 2,149 studies for Periodontitis. How that becomes 1,229 here

This page counts the studies the registry files under Periodontitis, and those it files under no condition that list Periodontitisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,149Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −675Filed under a narrower condition, counted on its own pageChronic Periodontitis 276 · Periapical Periodontitis 238 · Periodontal Pocket 61 · Aggressive Periodontitis 36
  3. −40List Periodontitis as a condition, but the registry did not file them under itMost often written as “Chronic Apical Periodontitis” (8), “Asymptomatic Apical Periodontitis” (7), and “Symptomatic Apical Periodontitis” (5). The registry filed them under other conditions only, most often Pain, Postoperative (22) and Dental Pulp Necrosis (5).
  4. −205Match it another way180 name it in the title, 6 in a keyword, and 19 by a synonym or other text the search reads.
  5. 1,229The count on this page12 of them list Periodontitis in their own words; the registry filed them under no condition.

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Status

Completed
711
Recruiting
158
Status unknown
149
Not yet recruiting
116
Active, not recruiting
58
Enrolling by invitation
21

Phase

Phase 2
72
Phase 4
65
Phase 3
44
Phase 1
34
Early Phase 1
26

Where

Turkey
260
Egypt
118
Italy
85
United States
75
India
70
Brazil
48

Who runs them

Postgraduate Institute of Dental Sciences Rohtak (34) · Cairo University (34) · Ain Shams University (22) · Saglik Bilimleri Universitesi (16) · University of Baghdad (15) · Ondokuz Mayıs University (15) · Marmara University (14) · University of Catania (14)

What is being tested here

Drugs under test in Periodontitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Hyaluronic Acid318
Chlorhexidine2213
P-prf105
Omega-3 fatty acid103
Aspirin102
Melatonin102
Dexamethasone101
LP-005101
Holy basil leaf extract111
Quercetin101

Drug classes tested here NSAIDs 1 open

Coming up

6phase 3 studies under way
86studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 158 Periodontitis studies recruiting now, 78 (49%) set no upper age limit and 60 (38%) stop at 75 or younger. 12 (8%) take children under 18. 2 (1%) are for women only and 0 (0%) for men only; 76 (48%) take healthy volunteers.

Recruiting studies that take each age, of 158
AgeWomenMen
108 (5%)7 (4%)
18124 (78%)122 (77%)
30151 (96%)149 (94%)
40155 (98%)153 (97%)
50149 (94%)148 (94%)
65137 (87%)136 (86%)
75101 (64%)100 (63%)
8584 (53%)83 (53%)

Across all 1,231 studies, recruiting or not: 57% stop at 75 or younger and 43% at 65; 9% take children; 4% are for women only and 1% for men only; 52% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Periodontitis studies take

Of 30 phase 4 interventional studies under Periodontitis, half reached primary completion within 11 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 112 mo6–19 · 27 studies——
Phase 215 mo8–21 · 18 studies——
Phase 411 mo7–22 · 30 studies—17 mo7–22 · 29 studies
Interventional, no phase16 mo8–31 · 494 studies—15 mo8–31 · 480 studies
Observational13 mo7–30 · 86 studies—17 mo7–30 · 85 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Newly registered19

Show 14 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,231. Browse all 1,231 → or search them.