Cairo University: Periodontitis trials

The registry lists 71 Periodontitis studies with Cairo University as lead sponsor. 18 are open to participants now and 1 have results posted.

Early Phase 1 5Phase 1 4Phase 2 4Phase 3 2No phase 59(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Minimally Invasive Non-Surgical Periodontal Therapy Alone vs. Minimally Invasive Non-Surgical Periodontal Therapy With I-PRF With or Without Chlorhexidine on Stage III Periodontitis PatientsNot yet recruitingNCT07791238Phase 1/2
• Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DMNot yet recruitingNCT07753317Not applicable
• Surfactant Protein D Levels in GCF Before and After MINST in PeriodontitisRecruitingNCT07599657Not applicable
• Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical TrialNot yet recruitingNCT07090265Phase 3
• Assessment of Pro-Resolution Mediator Levels in Periodontitis Stage III and IV Before and After Periodontal TherapyRecruitingNCT06789458Not applicable
• Evaluation of an Algae-Based Biphasic Bone Graft Material and Collagen Membrane in the Treatment of Periodontal Intrabony DefectsEnrolling by invitationNCT06633640Early Phase 1
• Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III PeriodontitisNot yet recruitingNCT06570200Phase 2
• Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With Erythritol Powder vs Conventional InstrumentationRecruitingNCT06490679Not applicable
• The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical TrialNot yet recruitingNCT06396130Not applicable
• Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP StudyNot yet recruitingNCT06371560
• Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual ScalersRecruitingNCT06351982Not applicable
• Clinical and Radiographic Evaluation of Using the Entire Papilla Preservation Technique With and Without Autogenous Bone Graft and Injectable Platelet Rich Fibrin in Treatment of Periodontal Intraosseous DefectsRecruitingNCT06347263Not applicable
• Clinical Evaluation of Injectable Alb-PRF in the Management of Intrabony Defect in Stage-III Periodontitis PatientsNot yet recruitingNCT06297577Not applicable
• Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich FibrinNot yet recruitingNCT06086249Not applicable
• Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy IndividualsRecruitingNCT06048016Not applicable
• Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp TreatmentsRecruitingNCT05902936Not applicable
• Effect of Injectable Platelet Rich Fibrin Augmented With Vitamin C Compared to Injectable Platelet Rich Fibrin Alone on Healing of Necrotic Mature Single Rooted Teeth With Chronic Peri-apical Periodontitis Following Regenerative Endodontics (A Randomized Controlled Trial)Not yet recruitingNCT05585359Not applicable
• The Link Between Periodontitis, Smoking and Oral CancerNot yet recruitingNCT04047212
• Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony DefectsCompletedNCT02248103Not applicableResults posted
• Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV PeriodontitisActive, not recruitingNCT07731113Not applicable
• Clinical Evaluation of Nano-Hydroxyapatite as an Adjunctive to Minimally Invasive Non-Surgical Technique in the Treatment of Deep Intra-bony DefectsActive, not recruitingNCT07608783Not applicable
• Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical TechniqueActive, not recruitingNCT07595757Phase 1/2
• Assessment the Efficacy of Curcumin Local Delivery Gel in Treatment of Periodontitis in SmokersCompletedNCT06653231Early Phase 1
• Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical PeriodontitisCompletedNCT05653947Not applicable
• Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Status unknownNCT05582421Early Phase 1
• BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.Status unknownNCT05555420Not applicable
• Ozone Gel Application in Controlled Type 2 Diabetic Patients With PeriodontitisStatus unknownNCT05538078Not applicable
• Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8CompletedNCT05525013Not applicable
• Prevalence of Periodontitis Based Upon Principles Presented by the 2017 Classification: A Hospital-based Cross-sectional Study on a Sample of Young Egyptian Dental PatientsStatus unknownNCT05441397
• Effect of Adjunctive Use of Vitamin B3 and B9 on Myeloperoxidase Level in the GCF of Patients With Stage I and II PeriodontitisStatus unknownNCT05435378Early Phase 1
• Prevalence of Periodontitis in Diabetic Patients of Egyptian PopulationStatus unknownNCT05322369
• Prevalence of Periodontitis in Sample of Egyptian PopulationCompletedNCT05317208
• Association Between Periodontitis and Coronavirus Disease (COVID-19)CompletedNCT05278468
• Evaluation of iPRF With Vitamin C in StageII Grade A PeriodontitisStatus unknownNCT05129267Not applicable
• The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With PeriodontitisStatus unknownNCT05009355Early Phase 1
• Levels of Neuregulin-4 and Its Receptor ErbB4 in Periodontitis Patients With and Without Diabetes Type 2Status unknownNCT04930588
• Cathelicidin LL-37 Levels in the GCF and the Saliva of Smokers and Non-smokers With Stage III,IV PeriodontitisCompletedNCT04861493
• Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.CompletedNCT04733326Phase 1
• Correlation Between Periodontitis and Hypertension Among a Sample of Adult Egyptian PatientsStatus unknownNCT04634734
• Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical PeriodontitisCompletedNCT04606719Not applicable
• Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical PeriodontitisStatus unknownNCT04594317Not applicable
• Serum Resistin Level Following Non-surgical Periodontal Therapy in Diabetic Patients With Chronic PeriodontitisCompletedNCT04473209Not applicable
• Comparison Between Two Non-surgical Periodontal Treatment Procedures With and Without Interdental Hygiene Devices in Periodontitis Patients: a Longitudinal Prospective Controlled Clinical TrialCompletedNCT04339309Not applicable
• Ketorolac Irrigant on Post Operative PainStatus unknownNCT04319549Not applicable
• Clinical and Radiographic Evaluation of NIPSA Versus M-MIST in Treatment of Intra-osseous DefectsStatus unknownNCT04149834Not applicable
• Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical TrialCompletedNCT04100798Not applicable
• Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical PeriodontitisCompletedNCT04018456Not applicable
• The Effect of A-PRF+ Versus Open Flap Debridement in the Treatment of Patients With Stage III PeriodontitisCompletedNCT03924336Not applicable
• The Effect of Zinc on the Gingival Crevicular Fluid Level of Total Oxidant Capacity in Type 2 Diabetic PatientsStatus unknownNCT03923829Not applicable
• Clinical Effect of APRF With DFDBA Compare to Collagen Membrane With DFDBA in Intraosseous DefectStatus unknownNCT03922503Not applicable
• Serum Hs-CRP in Periodontitis Patients With or Without DiabetesCompletedNCT03908606Not applicable
• Prevalence of Periodontitis on a Sample of Adult Egyptian PopulationStatus unknownNCT03901911
• Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous DefectsStatus unknownNCT03900013Not applicable
• Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2CompletedNCT03807596Not applicable
• Tissue Plasminogen Activator & Plasminogen Activator Inhibitor Type-1 In Gingival Tissues Of Chronic PeriodontitisCompletedNCT03803176
• Prevalence Of Periodontitis Stage III & IVCompletedNCT03779763
• Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony DefectsStatus unknownNCT03588507Not applicable
• Identification of EMT Indicators in Healthy and Periodontally Diseased Gingival SamplesStatus unknownNCT03462953Not applicable
• Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical PeriodontitisStatus unknownNCT03350841Not applicable
• Immediate Implant Placement in Aggressive PeriodontitisStatus unknownNCT03218228Not applicable
• Effect of Occlusal Reduction on Post-operative PainStatus unknownNCT03189771Not applicable
• Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal DiseaseCompletedNCT03128502
• Effect of Preoperative Clindamycin on Postoperative Endodontic PainStatus unknownNCT03033472Phase 2/3
• Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic PainCompletedNCT03033147Not applicable
• Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic PainStatus unknownNCT03007342Not applicable
• Single Versus Multiple Visits Endodontic TreatmentCompletedNCT02947763Phase 1
• Effect of Passive Ultrasonic Irrigation Versus Needle Irrigation on Postoperative Pain and Periapical HealingStatus unknownNCT02913937Not applicable
• Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony DefectsCompletedNCT02679209Not applicable
• Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony DefectsCompletedNCT02507596Not applicable
• Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal TherapyCompletedNCT02174146Not applicable
• Osteoprotegerin Before and After Periodontal SurgeryCompletedNCT02160613Not applicable