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Drug

Hyaluronic Acid clinical trials

Also written Sodium Hyaluronate and HA35.

Includes 2 studies of Restylane.

studies test it
187
open now
42
in phase 3
25
first study started
2002

Counted the way a researcher would: Hyaluronic Acid with its salts, dosage forms, brands and biosimilars.

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Keep track of what changes. Save the Hyaluronic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

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How studies write it

Studies that test it under each name

Name

Hyaluronic acid
64
Hyaluronic Acid (HA)
18
Hyaluronic acid gel
10
Gengigel
8
HA
6

Brand

Ostenil
1

Development codes

HA35
2
PRO-087
1
PRO-037
1
CTX-100
1
ETX-100
1

Other names

Sodium Hyaluronate
23
Hyaluronan
6
hyaluronate
2

Written with another drug

Hyaluronic Acid (HA) and Platelet rich plasma
1
oral hyaluronate and injection
1
Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash
1
Hyaluronic Acid and Chondroitin Sulfate
1
Triamcinolone Acetonide and sodium hyaluronate and chondroitin sulfate
1
Methylprednisolone and Hyaluronic acid
1
platelet rich plasma + Hyaluronic acid
1
hyaluronic Acid + platelet-rich plasma
1

Studies by the year they started

185 studies that test it; most in 2026 (19); 1 more planned to start later

Studies that test Hyaluronic Acid, by start year
YearStudies
20021
20031
20041
20053
20062
20075
20081
20096
20101
20113
20125
20139
201411
20154
20169
201712
20186
201911
202010
202113
202213
202315
20249
202515
202619

By phase

A phase 1/2 study counts in both.

Early Phase 1
10
Phase 1
15
Phase 2
28
Phase 3
25
Phase 4
50
No phase
74

What it is tested for

Each study’s main condition, where its own words name it.

Osteoarthritis, Knee
18
Osteoarthritis
13
Dry Eye Syndromes
9
Gingival Recession
6
Periodontitis
4
Bursitis
3
Cystitis, Interstitial
3
Shoulder Impingement Syndrome
3
Periodontal Pocket
3
Chronic Periodontitis
3
Glaucoma
3
Gingival Overgrowth
2

Who runs them

Industry 16 · Other 171

Cairo University (8) · Ain Shams University (6) · Assiut University (5) · Chang Gung Memorial Hospital (3) · Damascus University (3) · Taipei Veterans General Hospital, Taiwan (3) · Allergan (3) · Sanofi (3)

Often tested with

Tested in the same studies.

Platelet rich plasma (11) · Methylprednisolone (5) · Chondroitin Sulfates (4) · Adrenal Cortex Hormones (3) · Methylprednisolone Acetate (2) · Carboxymethylcellulose (2) · Hypromellose Derivatives (2) · P-prf (2)

Studies

Open first, then newest update. How each study uses Hyaluronic Acid is read from its arms, and is right about nine times in ten.

Testing it · 187

See all 187 studies that test Hyaluronic Acid →

Given in every arm · 10 — Hyaluronic Acid is usual care beside what is tested
As the comparator · 60 — what is tested is compared with Hyaluronic Acid

Showing 20 of 60.

Codes

What other systems call Hyaluronic Acid · ClinicalTrials.gg INT007622

  • MeSH (NLM) D006820Hyaluronic AcidConfirmed ClinicalTrials.gov, Wikidata
  • UNII (FDA) S270N0TRQYHYALURONIC ACIDConfirmed FDA, Wikidata
  • RxNorm 5463One source FDA
  • Wikidata Q337231hyaluronic acidConfirmed FDA, Wikidata
  • NCI Thesaurus C549Hyaluronic AcidOne source FDA
  • DrugBank DB08818One source Wikidata

Also registered as sodium hyaluronate (UNII YSE9PPT4TH · RxNorm 42892).

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.