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Periapical Periodontitis clinical trials

The registry lists 280 studies for Periapical Periodontitis across more than 10 countries. 79 are recruiting or about to start. 222 of them are mainly about Periapical Periodontitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
147
Recruiting
43
Not yet recruiting
34
Status unknown
25
Active, not recruiting
24
Enrolling by invitation
2

Phase

Phase 2
14
Phase 4
10
Phase 3
9
Early Phase 1
7
Phase 1
5

Where

Turkey
80
Egypt
37
India
24
United States
18
Pakistan
14
Italy
7

Who runs them

Postgraduate Institute of Dental Sciences Rohtak (31) · Cairo University (19) · Istanbul Medipol University Hospital (10) · Ain Shams University (8) · TC Erciyes University (8) · University of Siena (7) · Recep Tayyip Erdogan University (6) · Medipol University (6)

What is being tested here

Drugs under test in Periapical Periodontitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Metronidazole304
Ciprofloxacin203
Sodium Hypochlorite103
Hypochlorous Acid103
Calcium Hydroxide112
Chlorhexidine112
Minocycline102
Ferrosoferric Oxide102
Diclofenac112
P-prf101

Drug classes tested here NSAIDs 2 open

Coming up

5phase 3 studies under way
35studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 43 Periapical Periodontitis studies recruiting now, 17 (40%) set no upper age limit and 25 (58%) stop at 75 or younger. 5 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 21 (49%) take healthy volunteers.

Recruiting studies that take each age, of 43
AgeWomenMen
103 (7%)3 (7%)
1838 (88%)38 (88%)
3042 (98%)42 (98%)
4042 (98%)42 (98%)
5038 (88%)38 (88%)
6524 (56%)24 (56%)
7519 (44%)19 (44%)
8518 (42%)18 (42%)

Across all 280 studies, recruiting or not: 73% stop at 75 or younger and 66% at 65; 18% take children; 0% are for women only and 1% for men only; 50% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Periapical Periodontitis studies take

Of 172 interventional studies with no phase under Periapical Periodontitis, half reached primary completion within 12 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase12 mo6–19 · 172 studies—12 mo6–19 · 171 studies
Observational14 mo9–27 · 16 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Results posted1

Newly registered11

Show 6 more

Studies

Recruiting first, then most recently updated. Showing 50 of 280. Browse all 280 → or search them.