ClinicalTrials.gg
RecruitingNCT07574827Updated Nov 4, 2026

Candida Albicans in Syrian Patients With Periodontitis

An observational study in Periodontal Disease, Periodontal Diseases and Periodontitis, sponsored by Al-Hawash Private University. Recruiting at 1 site in Syria. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-04.

Primary conditionPeriodontitisRegistry: Periodontal DiseasesReclassifiedWhy we changed it
Registry
Periodontal Diseases — the first condition term the registry derived for this study.
ClinicalTrials.gg
Periodontitis
Why
  1. The study's listed conditions name Periodontitis, a narrower term within Periodontal Diseases.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Al-Hawash Private University · Observational

From the registry’s dates

  • Started Apr 2026; still recruiting 7 months later.
Updated Nov 4, 2026Primary completion movedStudy completion movedGo to Updates ↓
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth. Recent research has indicated that Candida albicans, a common fungal pathogen, may play a role in the exacerbation of periodontal diseases. This study aims to investigate the prevalence and impact of Candida albicans in Syrian patients diagnosed with periodontitis, contributing to a better understanding of its role in oral health within this population.

02

Conditions studied

  • Periodontal Disease
  • Periodontal Diseases
  • Periodontitis

Browse trials for

Keywords

  • Candida Albicans
  • Candida
  • Periodontitis
  • Sabouraud Dextrose Agar
  • Culture
03

In context

Periodontitis Reclassified

1,231 studies on the registry are indexed under Periodontitis; 295 are open to participants now.

This study's planned enrollment of 100 is above the median of 90 across 372 observational studies indexed under Periodontitis.

Browse Periodontitis studies →

Lead sponsor

Al-Hawash Private University is the lead sponsor of 6 studies on the registry; 4 are open to participants now.

Compared within Periodontitis, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Periodontal Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Syrian patients with periodontitis at Al-Hawash Private University Dental Clinics

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged 18 years and older.
  • Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth).
  • Consent to participate in the study.

Exclusion criteria

Exclusion Criteria:

  • Patients with systemic diseases affecting oral health (e.g., diabetes, conditions).
  • Recent antibiotic or antifungal treatment within the last three months.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)
Patient registry
No

Groups and cohorts

  • Syrian Patients With Periodontitis

    Diagnostic Test: Periodontal Assessment and Sample Collection from Subgingival Pockets

  • Syrian Individuals without Periodontal Disease

    Diagnostic Test: Periodontal Assessment and Sample Collection from Subgingival Pockets

Interventions

  • Diagnostic testPeriodontal Assessment and Sample Collection from Subgingival Pockets

    Clinical examination to assess periodontal status. Collection of subgingival plaque samples for microbiological analysis to identify Candida Albicans.

06

What researchers measure

Primary outcomes

  1. Detection of Candida Species in Subgingival Samples

    Time frame: At enrollment

Secondary outcomes

  1. Periodontal Screening and Recording Index

    Periodontal parameters are measured using the WHO probe by dividing the mouth into six sextants (three upper, three lower). The highest score in each sextant is recorded. Scoring from 0-4 is based on pocket depth, gingival health, and calculus presence. Scoring Criteria: 0: Healthy periodontium, black band visible. 1. Bleeding on probing (BOP), black band visible. 2. Calculus present, black band visible. 3. Pocket depth 3.5-5.5 mm (black band partially submerged). 4. Pocket depth \> 5.5 mm (black band entirely hidden).

    Time frame: At enrollment

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it moved

Started Apr 2026 (actual). Primary completion is estimated for Mar 2027, 11 months after the start.

Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 4, 2026: primary completion Aug 2026 → Mar 2027 and completion Sep 2026 → Sep 2027.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Apr 22, 2026
First posted
May 8, 2026
StartActual
Apr 7, 2026
Primary completionEst.
Mar 2027was Aug 2026
CompletionEst.
Sep 2027was Sep 2026
Last update
Nov 4, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Primary completion
Aug 2026→Mar 2027
Nov 4, 2026
Study completion
Sep 2026→Sep 2027
Nov 4, 2026
Show all 1 update
  1. Nov 4, 2026
    Primary completion Aug 2026→Mar 2027
    Study completion Sep 2026→Sep 2027
    + 1 other change: verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07574827
Lead sponsor
Al-Hawash Private University
Responsible party
Sponsor
First posted
May 8, 2026
Start date
Apr 7, 2026
Primary completion
Mar 2027 (estimated)
Completion
Sep 2027 (estimated)
Last update
Nov 4, 2026

Study contacts

Ali Abou Sulaiman
Contact
dr.ali.abousulaiman@hpu.edu.sy
+963956790836
Ali Abou Sulaiman, Ph.D. in Periodontology
principal investigator · Al-Hawash Private University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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