Musculoskeletal Diseases clinical trials
The registry lists 752 studies for Musculoskeletal Diseases across more than 10 countries. 164 are recruiting or about to start. 328 of them are mainly about Musculoskeletal Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 186 narrower conditions too, such as Arthritis, Rheumatoid: 31,040 studies, 6,118 open.
ClinicalTrials.gov finds 28,608 studies for Musculoskeletal Diseases. How that becomes 750 here
This page counts the studies the registry files under Musculoskeletal Diseases, and those it files under no condition that list Musculoskeletal Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 28,608Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −26,836Filed under a narrower condition, counted on its own pageArthritis, Rheumatoid 3,262 · Osteoarthritis, Knee 3,160 · Osteoarthritis 1,739 · Osteoporosis 1,495 · Fibromyalgia 1,179 · Shoulder Pain 667 · 171 more
- −23List Musculoskeletal Diseases as a condition, but the registry did not file them under itMost often written as “Orthopedic Disorder of Spine” (10), “Chronic Musculoskeletal Disease” (8), and “Musculoskeletal Disease Other” (2). The registry filed 9 of them under no condition at all, and the others under other conditions only, most often Chronic Pain (5) and Nervous System Diseases (1).
- −999Match it another way4 name it in the title and 995 by a synonym or other text the search reads.
- 750The count on this page
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Research Centre for the Working Environment, Denmark (14) · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio (13) · AbbVie (13) · Afyonkarahisar Health Sciences University (10) · Chinese University of Hong Kong (10) · QED Therapeutics, a BridgeBio company (8) · BioMarin Pharmaceutical (8) · Cairo University (8)
What is being tested here
Drugs under test in Musculoskeletal Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 3 open · Local anesthetics 2 open · Antifibrinolytics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027An Interventional Study of Infigratinib in Children With Hypochondroplasia · Phase 3 · QED Therapeutics, a BridgeBio company
- Aug 2027Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery. · Phase 3 · Walter Reed National Military Medical Center
- Dec 2026SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization · CrannMed
- Dec 2026Manual Therapy and Physical-sport Performance · University of La Laguna
- Dec 2026Posture Protection Program for Musculoskeletal Disorders and Ergonomic Risk in Hospital Cleaning Staff · Akdeniz University
- Dec 2026IAMABLE: Implementation and Evaluation of an App for Evidence-Based Self-Management Rehabilitation Strategies · McMaster University
- Dec 2026Original Medical Notes Versus AI Plain-Language Summaries · University of Texas at Austin
- Dec 2026Reflex Therapy of Temporomandibular Dysfunctions · Palacky University
- Dec 2026Expressive Art Therapy for Elder Adults With Chronic Low Back Pain · The Hong Kong Polytechnic University
- Dec 2026Art Therapy for Adults With Chronic Low Back Pain · The Hong Kong Polytechnic University
Who these studies take
Of the 100 Musculoskeletal Diseases studies recruiting now, 39 (39%) set no upper age limit and 44 (44%) stop at 75 or younger. 21 (21%) take children under 18. 0 (0%) are for women only and 1 (1%) for men only; 22 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 17 (17%) | 18 (18%) |
| 18 | 76 (76%) | 76 (76%) |
| 30 | 80 (80%) | 80 (80%) |
| 40 | 82 (82%) | 82 (82%) |
| 50 | 83 (83%) | 83 (83%) |
| 65 | 80 (80%) | 80 (80%) |
| 75 | 66 (66%) | 66 (66%) |
| 85 | 53 (53%) | 53 (53%) |
Across all 752 studies, recruiting or not: 47% stop at 75 or younger and 35% at 65; 20% take children; 5% are for women only and 3% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Musculoskeletal Diseases studies take
Of 30 phase 2 interventional studies under Musculoskeletal Diseases, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 34 mo21–66 · 30 studies | — | — |
| Phase 3 | 28 mo23–44 · 27 studies | 26 mo22–44 · 26 studies | — |
| Interventional, no phase | 16 mo6–36 · 266 studies | — | 16 mo6–38 · 251 studies |
| Observational | 27 mo7–74 · 107 studies | — | 18 mo7–60 · 86 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Activity Post Spinal Surgery Engagement TrialOct 22, 2026NCT07825480
Stopped1
- Evaluation of a Connected Interface to Improve the Quality of Life and the Disability of Patient With Rheumatic DiseasesTerminatedNov 10, 2026NCT05417477
Newly registered5
- Breaking the Cycle of Pain With Clinical PilatesNov 10, 2026NCT07929324
- Home-Based Corrective Exercise With Remote Reinforcement for Upper Crossed SyndromeNov 9, 2026NCT07924995
- Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal DisordersOct 29, 2026NCT07903142
- Effect of a Constipation Prevention Checklist in Hip Surgery PatientsOct 26, 2026NCT07895316
- Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal ConditionsOct 19, 2026NCT07880210
Studies
Recruiting first, then most recently updated. Showing 50 of 752. Browse all 752 → or search them.
- CERAMENT™| Bone Void Filler Device RegistryRecruitingNCT042449421 country
- Breaking the Cycle of Pain With Clinical PilatesNot yet recruitingNCT079293241 country
- Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and DeformitiesRecruitingNCT06380530Not applicable1 country
- A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 SkippingRecruitingNCT07587242Phase 310 countries
- Pediatric Orthopaedic Implant Safety & EfficacyRecruitingNCT053619801 country
- Home-Based Corrective Exercise With Remote Reinforcement for Upper Crossed SyndromeNot yet recruitingNCT07924995Not applicable
- Prospective RCT Lidocaine & Levobupivacaine on Block Dynamics After Subparaneural Popliteal Sciatic Nerve BlockRecruitingNCT04397484Phase 41 country
- Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: Selective Trunk Block vs Supraclavicular Brachial Plexus BlockRecruitingNCT05649644Not applicable1 country
- ITPB 1 vs 3 in VATSRecruitingNCT06838793Not applicable1 country
- A First-in-human Study of KK8123 in Adults With X-linked HypophosphatemiaRecruitingNCT06525636Phase 1/25 countries
- Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk BlockRecruitingNCT04941664Not applicable1 country
- A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the AnkleRecruitingNCT06915233Phase 31 country
- Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal DisordersNot yet recruitingNCT07903142Not applicable1 country
- Effect of a Constipation Prevention Checklist in Hip Surgery PatientsRecruitingNCT07895316Not applicable1 country
- Extension Study of Infigratinib in Children With Achondroplasia (ACH)Enrolling by invitationNCT05145010Phase 210 countries
- Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With AchondroplasiaRecruitingNCT07441876Phase 2/39 countries
- Activity Post Spinal Surgery Engagement TrialRecruitingNCT07825480Not applicable1 country
- The Effects of AFO Heel Height and Stiffness on GaitRecruitingNCT04800484Not applicable1 country
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal ConditionsNot yet recruitingNCT078802101 country
- SmaRTWork - a Decision Support System to Promote Return to Work Among People Sick-listed With Musculoskeletal DisordersNot yet recruitingNCT07034040Not applicable1 country
- A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type IEnrolling by invitationNCT06926621Phase 28 countries
- Managed Access Program for Del-zota in Participants With DMD Mutations Amenable to Exon 44 SkippingAvailableNCT072507371 country
- Pre-Op THA ModellingRecruitingNCT05221554Not applicable1 country
- Human Tendon Tissue CollectionNot yet recruitingNCT076060921 country
- Right-Size Clinic Visits Using Memora Platform for PROMISRecruitingNCT04441567Not applicable1 country
- Exercise and Health Education for Musculoskeletal Health in Industrial WorkersRecruitingNCT07844707Not applicable1 country
- Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked PainNot yet recruitingNCT07101978Not applicable1 country
- X-BS Ortho Bone Graft StudyNot yet recruitingNCT06326827Not applicable
- Translation, Cultural Adaptation, and Standardization of E-NMQRecruitingNCT076266191 country
- Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal TestNot yet recruitingNCT07158892Not applicable1 country
- Orthobiological Therapies in Musculoskeletal DisordersRecruitingNCT07434115Early Phase 11 country
- Autologous Bone Marrow Aspirate Treatment for Early-Stage OsteonecrosisRecruitingNCT06123481Not applicable1 country
- A Study to Compare Early and Partial Weight-bearing After Hallux Valgus SurgeryRecruitingNCT05534724Not applicable1 country
- Reducing Physical Workload Among Assistant Nurses Through Ergonomic Work Technique Training With or Without BiofeedbackNot yet recruitingNCT07805629Not applicable
- Longevity Metrics AI/ML Development StudyRecruitingNCT078086191 country
- Human Observatory StudyRecruitingNCT076467821 country
- 100-Year Human Aging StudyRecruitingNCT075637771 country
- Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic PainRecruitingNCT06004804Not applicable1 country
- Back on Track: Evaluation of an Occupational Reintegration Protocol for Employees With Musculoskeletal DisordersRecruitingNCT077935261 country
- Video-based First-contact Physiotherapy in Primary CareNot yet recruitingNCT07788651Not applicable
- Open-Label, Long-Term, Extension Study of Infigratinib in Children With HypochondroplasiaEnrolling by invitationNCT07393373Phase 210 countries
- Musculoskeletal Ultrasound in Patients With Hematologic MalignanciesNot yet recruitingNCT07785505
- A Pragmatic Trial of EAET for Veterans With Chronic PainRecruitingNCT07218757Not applicable1 country
- Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.RecruitingNCT07151417Phase 2/31 country
- Fecal Microbiota Transplantation in Axial SpondyloarthritisRecruitingNCT06451588Phase 21 country
- Reflex Therapy of Temporomandibular DysfunctionsRecruitingNCT07321483Not applicable1 country
- Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI TrialNot yet recruitingNCT07742553Phase 2/31 country
- Shoulder Health After Rehabilitation and Performance TrainingRecruitingNCT07245706Not applicable1 country
- Reducing Pain-Related Sickness Absence Through Workplace Health Literacy: A Hybrid II StudyNot yet recruitingNCT07707180Not applicable