Muscular Diseases clinical trials
The registry lists 232 studies for Muscular Diseases across more than 10 countries. 54 are recruiting or about to start. 98 of them are mainly about Muscular Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 43 narrower conditions too, such as Fibromyalgia: 6,992 studies, 1,563 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (7) · Novartis Pharmaceuticals (5) · Assiut University (4) · Beth Israel Deaconess Medical Center (4) · University of Sao Paulo (4) · Vanderbilt University Medical Center (4) · Institut de Myologie, France (3) · Vanderbilt University (3)
What is being tested here
Drugs under test in Muscular Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026The Natural History and Muscle Fatigability of Patients With Congenital Myopathies. · Radboud University Medical Center
- Nov 2026Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness · Technical University of Munich
- Dec 2026Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases · IRCCS Eugenio Medea
- Dec 2026The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy · University of Alabama at Birmingham
- Jan 2027WiTNNess - TNNT1 Myopathy Natural History Study · Clinic for Special Children
- Feb 2027A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1) · Vertex Pharmaceuticals Incorporated
- Mar 2027Emotional Release After Trigger Point Needling to Treat Myofascial Pain of the Head and Neck - Prospective Study · Tel-Aviv Sourasky Medical Center
- Apr 2027Temporomandibular Disorder (TMD) Diagnostic Concordance Between Physiotherapist and Surgeon · McGill University Health Centre/Research Institute of the McGill University Health Centre
- May 2027A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis. · AstraZeneca
- Jun 2027Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis · University of Nebraska
Who these studies take
Of the 38 Muscular Diseases studies recruiting now, 21 (55%) set no upper age limit and 10 (26%) stop at 75 or younger. 15 (39%) take children under 18. 0 (0%) are for women only and 1 (3%) for men only; 8 (21%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 12 (32%) | 13 (34%) |
| 18 | 36 (95%) | 36 (95%) |
| 30 | 35 (92%) | 35 (92%) |
| 40 | 36 (95%) | 36 (95%) |
| 50 | 36 (95%) | 36 (95%) |
| 65 | 36 (95%) | 36 (95%) |
| 75 | 33 (87%) | 33 (87%) |
| 85 | 25 (66%) | 25 (66%) |
Across all 232 studies, recruiting or not: 32% stop at 75 or younger and 21% at 65; 34% take children; 2% are for women only and 10% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Muscular Diseases studies take
Of 42 interventional studies with no phase under Muscular Diseases, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo4–40 · 42 studies | — | 18 mo4–40 · 41 studies |
| Observational | 75 mo20–159 · 36 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Personalized Disease Modeling for Rare Genetic MyopathiesNov 3, 2026NCT07914049
Studies
Recruiting first, then most recently updated. Showing 50 of 232. Browse all 232 → or search them.
- Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued TreatmentRecruitingNCT07691970Phase 335 countries
- A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 SkippingRecruitingNCT07587242Phase 310 countries
- A Natural History Study of RYR1-Related DisordersRecruitingNCT062877621 country
- Personalized Disease Modeling for Rare Genetic MyopathiesEnrolling by invitationNCT079140491 country
- Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body MyositisRecruitingNCT078231011 country
- Study of Inherited Neurological DisordersRecruitingNCT000045682 countries
- A Trial to Compare Treatment With Surlorian (ARM210, S48168) to Placebo in Effects on Muscle Strength and Safety in Adults With Autosomal Dominant RYR1-related MyopathyRecruitingNCT07560020Phase 25 countries
- Study of Anitocabtagene Autoleucel in Participants With Non-Oncology Plasma Cell-Related DiseasesRecruitingNCT06626919Phase 11 country
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type IEnrolling by invitationNCT06926621Phase 28 countries
- Managed Access Program for Del-zota in Participants With DMD Mutations Amenable to Exon 44 SkippingAvailableNCT072507371 country
- A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Not yet recruitingNCT06792500Phase 1/21 country
- Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked PainNot yet recruitingNCT07101978Not applicable1 country
- Diaphragm Atrophy and Dysfunction in Mechanical VentilationRecruitingNCT052116611 country
- Data Collection of Standard Care of Patients in the EMG SectionRecruitingNCT050413871 country
- Annatto-derived GG for Statin-associated MyopathyRecruitingNCT05312424Phase 1/21 country
- A Phase I/II Study of Eque-cel in Subjects Withimmune-mediated Necrotizing MyopathyNot yet recruitingNCT07752264Phase 1/21 country
- The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing MyopathyRecruitingNCT06599697Phase 21 country
- A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune DiseasesRecruitingNCT07284797Phase 11 country
- Cystinosis and Mitochondrial MetabolismRecruitingNCT07319091Not applicable1 country
- Efficacy of KL1333 in Adult Patients With Primary Mitochondrial DiseaseRecruitingNCT05650229Phase 211 countries
- WiTNNess - TNNT1 Myopathy Natural History StudyRecruitingNCT063747191 country
- The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma SurvivorsEnrolling by invitationNCT05116137Not applicable1 country
- Non-invasive BCI-controlled Assistive DevicesRecruitingNCT05183152Not applicable1 country
- Temporomandibular Disorder (TMD) Diagnostic Concordance Between Physiotherapist and SurgeonNot yet recruitingNCT07560917Not applicable1 country
- A Phase 1b Study of Adenylosuccinic Acid (ASA-001) for Adenylosuccinate Synthase 1 (ADSS1) Deficient Myopathy.Enrolling by invitationNCT07412821Phase 11 country
- Muscle Health Measurements Using Electrical Impedance MyographyRecruitingNCT075029891 country
- An Open-Label Extension Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (FREEDOM-OLE)RecruitingNCT07220603Phase 21 country
- Natural History Study for Patients With Nemaline Myopathy in SpainRecruitingNCT074888061 country
- Critical Illness Weakness Outside the Intensive Care Unit.RecruitingNCT074783671 country
- Comparing the Effectiveness of Online vs. Face-to-face Physiotherapy for Treating Temporomandibular DisordersRecruitingNCT07474662Not applicable1 country
- Metabolomics Study on Postoperative Intensive Care Acquired Muscle WeaknessRecruitingNCT038107682 countries
- Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular DiseasesRecruitingNCT066668161 country
- Recovery From ICUAW Following Severe Respiratory and Cardiac FailureRecruitingNCT037534121 country
- Prevalence of Sarcopenia in Patients Admitted to ICU and Its Progression During Hospitalization.Enrolling by invitationNCT073033351 country
- Characterization of Familial Myopathy and Paget Disease of BoneRecruitingNCT011668541 country
- Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)RecruitingNCT013534301 country
- Dantrolene in Statin-induced MyopathyNot yet recruitingNCT06966843Phase 2/3
- Expanded Access Program for R007 (Probucol) Tablets in Adults With Mitochondrial Disease and Chronic Kidney DiseaseAvailableNCT069318341 country
- Myotubular and Centronuclear Myopathy Patient RegistryRecruitingNCT040643071 country
- Emotional Release After Trigger Point Needling to Treat Myofascial Pain of the Head and Neck - Prospective StudyEnrolling by invitationNCT069124381 country
- Impact of Sarcopenia on Dyspnea in Patients With AsthmaNot yet recruitingNCT06870890Not applicable1 country
- Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using PatientsNot yet recruitingNCT06834776
- Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune MyopathiesRecruitingNCT04678635Not applicable1 country
- Investigation of Grip Strength, Pain and Anxiety Levels in DentistsNot yet recruitingNCT06721117
- Acute Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune MyopathiesRecruitingNCT03749538Not applicable1 country
- Clinical and Functional Assessment of Patients With Inherited Non-Duchenne Myopathies in Sohag University HospitalRecruitingNCT065749191 country
- The Natural History and Muscle Fatigability of Patients With Congenital Myopathies.RecruitingNCT061572681 country
- Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathyRecruitingNCT039985401 country
- Eficacia Ventilatoria y RemolachaRecruitingNCT06217211Not applicable1 country