Joint Diseases clinical trials

The registry lists 386 studies for Joint Diseases across more than 10 countries. 64 are recruiting or about to start. 114 of them are mainly about Joint Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 50 narrower conditions too, such as Arthritis, Rheumatoid: 14,989 studies, 2,797 open.

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Status

Completed: 210
Recruiting: 44
Status unknown: 35
Terminated: 35
Active, not recruiting: 25
Withdrawn: 17

Phase

Phase 2: 45
Phase 3: 39
Phase 4: 19
Phase 1: 19
Early Phase 1: 2

Where

United States: 149
Canada: 44
Spain: 44
Germany: 38
France: 28
Poland: 28

Who runs them

MicroPort Orthopedics Inc. (21) · AbbVie (13) · Zimmer Biomet (13) · Aesculap AG (9) · Universidad Católica San Antonio de Murcia (6) · Smith & Nephew, Inc. (6) · University of British Columbia (6) · Mayo Clinic (5)

What is being tested here

Drugs under test in Joint Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Dexamethasone	1	0	1
Triamcinolone	1	0	1
Upadacitinib	0	6	9
Platelet rich plasma	0	0	4
Bupivacaine	0	0	4
Rilonacept	0	4	4
Adalimumab	0	2	3
Tranexamic Acid	0	1	3
Certolizumab Pegol	0	2	3
Tapentadol	0	2	2

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 15 · JAK inhibitors 12 · Local anesthetics 6 · NSAIDs 4 · Antifibrinolytics 3

Coming up

6phase 3 studies under way

21studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Dec 2026SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization · CrannMed
Dec 2026Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty · Luzerner Kantonsspital
Dec 2026A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants · Dr. Reddy's Laboratories Limited
Dec 2026Prospective Post-market Study Examining the Effectiveness of the EcoFit® · Implantcast North America, LLC
Jan 2027Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis · University of Karachi
Apr 2027Vibratory Anesthesia on Pain Following Corticosteroid Injections · The University of Texas Medical Branch, Galveston
Apr 2027Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE) · University of Alberta
May 2027Fecal Microbiota Transplantation in Axial Spondyloarthritis · University Hospital of North Norway
May 2027MRI of the TMJ in Patients With DJD · University of Minnesota
May 2027Frozen Shoulder Treatment With Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block · Universitair Ziekenhuis Brussel

Who these studies take

Of the 44 Joint Diseases studies recruiting now, 24 (55%) set no upper age limit and 11 (25%) stop at 75 or younger. 3 (7%) take children under 18. 0 (0%) are for women only and 1 (2%) for men only; 1 (2%) take healthy volunteers.

Recruiting studies that take each age, of 44
Age	Women	Men
10	3 (7%)	3 (7%)
18	27 (61%)	28 (64%)
30	31 (70%)	32 (73%)
40	37 (84%)	38 (86%)
50	41 (93%)	42 (95%)
65	40 (91%)	41 (93%)
75	38 (86%)	38 (86%)
85	31 (70%)	31 (70%)

Across all 386 studies, recruiting or not: 29% stop at 75 or younger and 15% at 65; 12% take children; 1% are for women only and 7% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Joint Diseases studies take

Of 19 phase 3 interventional studies under Joint Diseases, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Phase 3	28 mo23–38 · 19 studies	—	—
Interventional, no phase	28 mo13–59 · 99 studies	—	26 mo12–57 · 80 studies
Observational	62 mo28–153 · 58 studies	—	—

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

The restor3d Outcomes RegistryOct 27, 2026NCT07563803

Newly registered1

Low-Dose Radiotherapy for Painful Knee OsteoarthritisOct 21, 2026NCT07886697

Studies

Recruiting first, then most recently updated. Showing 50 of 386. Browse all 386 → or search them.