Arthritis, Rheumatoid clinical trials
The registry lists 3,334 studies for Arthritis, Rheumatoid across more than 10 countries. 444 are recruiting or about to start. 2,805 of them are mainly about Arthritis, Rheumatoid (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as Sjogren's Syndrome: 3,639 studies, 523 open.
ClinicalTrials.gov finds 3,810 studies for Arthritis, Rheumatoid. How that becomes 3,332 here
This page counts the studies the registry files under Arthritis, Rheumatoid, and those it files under no condition that list Arthritis, Rheumatoidthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 3,810Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −296Filed under a narrower condition, counted on its own pageSjogren's Syndrome 276 · Still's Disease, Adult-Onset 20
- −56List Arthritis, Rheumatoid as a condition, but the registry did not file them under itMost often written as “Juvenile Rheumatoid Arthritis” (18), “Rheumatoid Arthritis of Knee” (8), and “Rheumatoid Arthritis Shoulder” (5). The registry filed them under other conditions only, most often Arthritis, Juvenile (23) and Arthritis (10).
- −126Match it another way81 name it in the title, 12 in a keyword, and 33 by a synonym or other text the search reads.
- 3,332The count on this page44 of them list Arthritis, Rheumatoid in their own words; the registry filed them under no condition.
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· Enrollment: 300 → 450 participants
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Status
Who runs them
Hoffmann-La Roche (185) · Pfizer (125) · Bristol-Myers Squibb (89) · Zimmer Biomet (59) · Amgen (56) · Assiut University (49) · AbbVie (46) · GlaxoSmithKline (40)
What is being tested here
Drugs under test in Arthritis, Rheumatoid studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tofacitinib | 9 | 11 | 43 |
| Methotrexate | 8 | 48 | 113 |
| Baricitinib | 5 | 8 | 23 |
| Tocilizumab | 4 | 65 | 109 |
| Adalimumab | 4 | 37 | 85 |
| Etanercept | 4 | 20 | 69 |
| Rituximab | 4 | 27 | 62 |
| GLPG0634 | 4 | 5 | 17 |
| Abatacept | 3 | 26 | 62 |
| Upadacitinib | 3 | 8 | 19 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 17 open · JAK inhibitors 17 open · Antimetabolites 9 open · Antihistamines 4 open · SGLT2 inhibitors 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis · Phase 3 · University Hospital, Montpellier
- Dec 2026"Effect of Vitamin E (α-Tocopherol) on Clinical Activity and Inflammation in Rheumatoid Arthritis" · Phase 3 · University of Guadalajara
- Dec 2026A Long-term Extension Clinical Study of TLL-018 in Patients With Rheumatoid Arthritis · Phase 3 · Hangzhou Highlightll Pharmaceutical Co., Ltd
- Jan 2027the Effect of Ginkgo Biloba on Rheumatoid Arthritis Patients · Phase 3 · Ain Shams University
- Feb 2027Nicorandil in Atherosclerosis Risk in Patients With Rheumatoid Arthritis · Phase 3 · Tanta University
- Mar 2027Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis · Phase 3 · University Hospital, Bordeaux
- Jul 2027The Effect of Nicorandil on Rheumatoid Arthritis Patients · Phase 3 · Ain Shams University
- Nov 2026Dysphagia in Rheumatoid Arthritis · Tanta University
- Nov 2026Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis · Sonoma Biotherapeutics, Inc.
- Nov 2026Comparison of Oral Administration of a JAK Inhibitor in Rheumatoid Arthritis · Centre Hospitalier Princesse Grace
Who these studies take
Of the 293 Arthritis, Rheumatoid studies recruiting now, 150 (51%) set no upper age limit and 109 (37%) stop at 75 or younger. 15 (5%) take children under 18. 7 (2%) are for women only and 2 (1%) for men only; 36 (12%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 11 (4%) | 10 (3%) |
| 18 | 258 (88%) | 253 (86%) |
| 30 | 283 (97%) | 278 (95%) |
| 40 | 286 (98%) | 281 (96%) |
| 50 | 288 (98%) | 284 (97%) |
| 65 | 271 (92%) | 269 (92%) |
| 75 | 214 (73%) | 213 (73%) |
| 85 | 171 (58%) | 170 (58%) |
Across all 3,334 studies, recruiting or not: 30% stop at 75 or younger and 13% at 65; 6% take children; 3% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Arthritis, Rheumatoid studies take
Of 158 phase 2 interventional studies under Arthritis, Rheumatoid, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 16 mo5–32 · 148 studies | 13 mo5–32 · 128 studies | — |
| Phase 1/2 | 22 mo12–26 · 29 studies | — | — |
| Phase 2 | 18 mo13–30 · 158 studies | 17 mo13–24 · 116 studies | 43 mo13–49 · 42 studies |
| Phase 3 | 26 mo17–40 · 148 studies | 24 mo16–31 · 116 studies | — |
| Phase 4 | 42 mo25–74 · 104 studies | 26 mo16–44 · 25 studies | 49 mo30–92 · 79 studies |
| Interventional, no phase | 27 mo13–47 · 348 studies | 61 mo26–92 · 56 studies | 24 mo12–39 · 292 studies |
| Observational | 50 mo25–113 · 391 studies | 61 mo32–116 · 155 studies | 43 mo19–122 · 236 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting2
- Study of PTC844 in Participants With Active Rheumatoid ArthritisNov 6, 2026NCT07779616
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyNov 3, 2026NCT07829497
Stopped2
- Evaluation of a Connected Interface to Improve the Quality of Life and the Disability of Patient With Rheumatic DiseasesTerminatedNov 10, 2026NCT05417477
- Microbiota Analysis to Predict Outcomes of Rheumatoid Arthritis Patients Treated With JAK-inhibitorSuspendedOct 26, 2026NCT04530305
Newly registered15
- Evaluation of the Effects of Anti-TNF Therapy on the Retina in Patients With Rheumatoid Arthritis and Ankylosing SpondylitisNov 12, 2026NCT07931352
- An Open-label Phase I/II Safety and Feasibility Basket Study of UKT-CART19.1Nov 12, 2026NCT07932262
- An Ascending Dose Study of DKB903 in Participants With Rheumatoid Arthritis (RA) and Participants With Systemic Lupus Erythematosus (SLE)Nov 6, 2026NCT07923747
- GenAI-Assisted Rheumatoid Arthritis Bone Erosion Risk Assessment and DMARD SelectionNov 4, 2026NCT07914907
- Overactive Bladder Symptoms and Urinary Incontinence In Women With Rheumatoid ArthritisNov 4, 2026NCT07916623
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- The Impact of Rheumatoid Arthritis Treatments on the Modulation of Extracellular Vesicles and Other Biomarkers Involved in the Development of Lung CancerNov 3, 2026NCT07913256
- A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune DiseasesOct 30, 2026NCT07906145
- Platform Study of Targeted Therapies for Adults With Moderately to Severely Active Rheumatoid ArthritisOct 29, 2026NCT07904754
- Effects of Paraffin Wax Therapy and Dry Cupping on Pain and Wrist Function in Patients With Rheumatoid ArthritisOct 29, 2026NCT07905651
- Efficacy and Safety of Dapagliflozin as an Adjunct to Conventional Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid ArthritisOct 28, 2026NCT07901309
- MYTP01 for Immune-Mediated DiseasesOct 28, 2026NCT07901764
- A Clinical Trial of MK-8690 in Participants With Rheumatoid Arthritis (MK-8690-004)Oct 26, 2026NCT07895524
- Musclockeletal Ultra-sound Assessment of Pulley Inflammation in Rheumatoid Arthrits PateintsOct 16, 2026NCT07878611
- HRV Variation in Rheumatoid ArthritisOct 16, 2026NCT07878975
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesOct 14, 2026NCT07873931
Studies
Recruiting first, then most recently updated. Showing 50 of 3,334. Browse all 3,334 → or search them.
- Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint InhibitorsRecruitingNCT047513961 country
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 12 countries
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyRecruitingNCT078294971 country
- An Open-label Phase I/II Safety and Feasibility Basket Study of UKT-CART19.1Not yet recruitingNCT07932262Phase 1/21 country
- A Study of AZD0120 in Autoimmune DiseasesRecruitingNCT07295847Phase 1/26 countries
- Platform Study of Targeted Therapies for Adults With Moderately to Severely Active Rheumatoid ArthritisNot yet recruitingNCT07904754Phase 2
- Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)RecruitingNCT07611747Phase 41 country
- An Ascending Dose Study of DKB903 in Participants With Rheumatoid Arthritis (RA) and Participants With Systemic Lupus Erythematosus (SLE)Not yet recruitingNCT07923747Phase 1
- Study of PTC844 in Participants With Active Rheumatoid ArthritisRecruitingNCT07779616Phase 24 countries
- Effect of Anti-inflammatory Diet in Rheumatoid ArthritisRecruitingNCT04748809Not applicable1 country
- A Trial in Healthy Adult Participants and Adults With Autoimmune Diseases to Test How HBM7020 is Tolerated and How it Behaves in the BodyRecruitingNCT07649265Phase 11 country
- MYTP01 for Immune-Mediated DiseasesNot yet recruitingNCT07901764Not applicable1 country
- Ultrasound to Guide Treatment Decisions in Patients With Rheumatoid Arthritis According to a T2T ApproachRecruitingNCT05717179Not applicable1 country
- GenAI-Assisted Rheumatoid Arthritis Bone Erosion Risk Assessment and DMARD SelectionRecruitingNCT07914907Not applicable1 country
- EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))RecruitingNCT06631638Not applicable1 country
- The Impact of Rheumatoid Arthritis Treatments on the Modulation of Extracellular Vesicles and Other Biomarkers Involved in the Development of Lung CancerNot yet recruitingNCT07913256
- Effects of Paraffin Wax Therapy and Dry Cupping on Pain and Wrist Function in Patients With Rheumatoid ArthritisNot yet recruitingNCT07905651Not applicable1 country
- A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)RecruitingNCT07363590Phase 111 countries
- A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune DiseasesNot yet recruitingNCT07906145Phase 1
- A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)RecruitingNCT06733935Phase 1/21 country
- Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE ParticipantsRecruitingNCT07201558Phase 110 countries
- Efficacy and Safety of Dapagliflozin as an Adjunct to Conventional Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid ArthritisNot yet recruitingNCT07901309Phase 1/21 country
- COVID-19 Booster and IIV Schedule in Immunocompromised HostsRecruitingNCT06599658Phase 21 country
- A Clinical Trial of MK-8690 in Participants With Rheumatoid Arthritis (MK-8690-004)Not yet recruitingNCT07895524Phase 2
- A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)RecruitingNCT07409103Phase 23 countries
- A Study of BMS-986528 in Participants With Refractory Rheumatoid ArthritisRecruitingNCT07412704Phase 1/211 countries
- Nutrition in Rheumatoid ArthritisEnrolling by invitationNCT06831331Not applicable1 country
- Acceptability of a Nurse-led Telehealth Remote Self-monitoring Model of Care in Patients With Rheumatoid ArthritisNot yet recruitingNCT07525856Not applicable1 country
- A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic DiseasesRecruitingNCT06647069Phase 15 countries
- A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic DiseasesRecruitingNCT07712939Phase 11 country
- A Clinical Study of YTS109 Cell in R/R Autoimmune DiseasesRecruitingNCT06978647Phase 11 country
- A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Rheumatoid ArthritisRecruitingNCT06994143Phase 12 countries
- A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)RecruitingNCT07607964Phase 12 countries
- Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion and Intra-Articular Injection for RARecruitingNCT05003934Phase 12 countries
- Functional Imaging of Digital Osteoarthritis and Rheumatoid Arthritis Using 99mTc-NTP 15-5 in Nuclear MedicineNot yet recruitingNCT07624994Phase 21 country
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- Controlling Hyperactive Immunity With Long-lived LymphocytesRecruitingNCT07473154Phase 1/23 countries
- An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid ArthritisRecruitingNCT07620392Phase 23 countries
- A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)RecruitingNCT07137598Phase 212 countries
- HRV Variation in Rheumatoid ArthritisRecruitingNCT078789751 country
- Musclockeletal Ultra-sound Assessment of Pulley Inflammation in Rheumatoid Arthrits PateintsNot yet recruitingNCT07878611
- A Comparison Study of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German Real-world SettINGRecruitingNCT067126281 country
- the Effect and Mechanism of Percutaneous Auricular Electrical Stimulation in Preventing Central Sensitization Pain in Patients With Rheumatoid ArthritisNot yet recruitingNCT07870564Not applicable
- Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory ArthritisNot yet recruitingNCT07865390Not applicable1 country
- A Study of F8IL10 Intra-articular Treatment in Rheumatoid ArthritisRecruitingNCT07245992Phase 11 country
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 16 countries
- Phase 1b/2 Study of IV Sarilumab in Adult With RARecruitingNCT07704580Phase 1/21 country
- A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid ArthritisRecruitingNCT07276581Phase 217 countries
- Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid ArthritisRecruitingNCT07274124Not applicable1 country
- A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid ArthritisRecruitingNCT06972446Phase 212 countries