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Temporomandibular Joint Disorders clinical trials

The registry lists 591 studies for Temporomandibular Joint Disorders across more than 10 countries. 149 are recruiting or about to start. 474 of them are mainly about Temporomandibular Joint Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Temporomandibular Joint Dysfunction Syndrome too: 619 studies, 155 open.

ClinicalTrials.gov finds 746 studies for Temporomandibular Joint Disorders. How that becomes 591 here

This page counts the studies the registry files under Temporomandibular Joint Disorders, and those it files under no condition that list Temporomandibular Joint Disordersthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 746Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −28Filed under a narrower condition, counted on its own pageTemporomandibular Joint Dysfunction Syndrome 28
  3. −9List Temporomandibular Joint Disorders as a condition, but the registry did not file them under itMost often written as “Myogenic Temporomandibular Joint Disorders” (2), “Temporomandibular Disorder Syndrome” (1), and “Laser and LED Therapy on Elderly Individuals With Temporomandibular Disorder” (1). The registry filed 6 of them under no condition at all, and the others under other conditions only, most often Facial Pain (2) and Pain (1).
  4. −118Match it another way37 name it in the title and 81 by a synonym or other text the search reads.
  5. 591The count on this page

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Status

Completed
346
Recruiting
75
Status unknown
69
Not yet recruiting
57
Enrolling by invitation
17
Active, not recruiting
12

Phase

Phase 2
41
Phase 3
16
Phase 1
15
Phase 4
13
Early Phase 1
6

Where

Turkey
150
Egypt
63
United States
59
Brazil
44
Spain
40
Poland
25

Who runs them

Cairo University (30) · University of Nove de Julho (15) · University of Minnesota (9) · Karolinska Institutet (8) · Hacettepe University (8) · Wroclaw Medical University (7) · Riphah International University (7) · Istanbul Medipol University Hospital (7)

What is being tested here

Drugs under test in Temporomandibular Joint Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Botulinum toxin type A3211
Lidocaine104
Hyaluronic Acid104
Glucose101
Coenzyme Q10101
Granisetron002
Platelet rich plasma002
Nortriptyline002
Ibuprofen002
Erenumab002

Drug classes tested here Local anesthetics 1 open · NSAIDs 5 · CGRP receptor antagonists 3

Coming up

3phase 3 studies under way
47studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 75 Temporomandibular Joint Disorders studies recruiting now, 26 (35%) set no upper age limit and 45 (60%) stop at 75 or younger. 7 (9%) take children under 18. 7 (9%) are for women only and 0 (0%) for men only; 23 (31%) take healthy volunteers.

Recruiting studies that take each age, of 75
AgeWomenMen
105 (7%)5 (7%)
1865 (87%)59 (79%)
3072 (96%)65 (87%)
4073 (97%)66 (88%)
5064 (85%)59 (79%)
6548 (64%)47 (63%)
7533 (44%)32 (43%)
8529 (39%)28 (37%)

Across all 591 studies, recruiting or not: 66% stop at 75 or younger and 59% at 65; 14% take children; 11% are for women only and 1% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Temporomandibular Joint Disorders studies take

Of 14 phase 2 interventional studies under Temporomandibular Joint Disorders, half reached primary completion within 22 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 222 mo7–39 · 14 studies——
Interventional, no phase10 mo5–21 · 246 studies—11 mo5–21 · 242 studies
Observational12 mo5–30 · 59 studies—12 mo4–30 · 57 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting3

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 591. Browse all 591 → or search them.