Rheumatic Diseases clinical trials
The registry lists 264 studies for Rheumatic Diseases across more than 10 countries. 60 are recruiting or about to start. 92 of them are mainly about Rheumatic Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 13 narrower conditions too, such as Arthritis, Rheumatoid: 11,488 studies, 2,002 open.
Get an email when these change. Save the Rheumatic Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
University of Sao Paulo General Hospital (5) · Novartis Pharmaceuticals (5) · National Institute of Medical Sciences and Nutrition, Salvador Zubiran (5) · Regeneron Pharmaceuticals (4) · University of Alabama at Birmingham (4) · University of Sao Paulo (4) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (4) · Assistance Publique - Hôpitaux de Paris (4)
What is being tested here
Drugs under test in Rheumatic Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Methotrexate | 1 | 1 | 4 |
| Canakinumab | 1 | 1 | 3 |
| Rituximab | 1 | 2 | 3 |
| Tofacitinib | 1 | 1 | 3 |
| Abatacept | 1 | 0 | 2 |
| Interleukin 1 Receptor Antagonist Protein | 1 | 0 | 2 |
| Secukinumab | 1 | 0 | 2 |
| Sulfasalazine | 1 | 0 | 1 |
| Hydroxychloroquine | 1 | 0 | 1 |
| Leflunomide | 1 | 0 | 1 |
Drug classes tested here Antimetabolites 1 open · Tyrosine kinase inhibitors (TKIs) 1 open · JAK inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization · CrannMed
- Dec 2026Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases · The Children's Hospital of Zhejiang University School of Medicine
- Dec 2026A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants · Dr. Reddy's Laboratories Limited
- Dec 2026Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea. · Novartis Pharmaceuticals
- Jan 2027Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic Disorders · Alexandra Miriam Kiess
- Apr 2027Effectiveness of a Combined e-Learning and Virtual Reality Training Program for Healthcare Providers in Rheumatology · Leiden University
- Apr 2027Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus · Michigan State University
- May 2027Calcium Pyrophosphate Deposition (CPPD) Disease · Lille Catholic University
- May 2027Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis · Medipol University
- Aug 2027A Study of IN026 in Participants With Refractory Gout · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Who these studies take
Of the 41 Rheumatic Diseases studies recruiting now, 18 (44%) set no upper age limit and 12 (29%) stop at 75 or younger. 7 (17%) take children under 18. 3 (7%) are for women only and 0 (0%) for men only; 11 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (15%) | 6 (15%) |
| 18 | 36 (88%) | 33 (80%) |
| 30 | 35 (85%) | 32 (78%) |
| 40 | 35 (85%) | 32 (78%) |
| 50 | 34 (83%) | 32 (78%) |
| 65 | 33 (80%) | 33 (80%) |
| 75 | 31 (76%) | 31 (76%) |
| 85 | 27 (66%) | 27 (66%) |
Across all 264 studies, recruiting or not: 31% stop at 75 or younger and 22% at 65; 16% take children; 4% are for women only and 1% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Rheumatic Diseases studies take
Of 74 interventional studies with no phase under Rheumatic Diseases, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 26 mo10–46 · 74 studies | — | 26 mo10–46 · 72 studies |
| Observational | 55 mo14–… · 36 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyNov 3, 2026NCT07829497
Studies
Recruiting first, then most recently updated. Showing 50 of 264. Browse all 264 → or search them.
- Studies of the Natural History of Rheumatic DiseasesRecruitingNCT000244791 country
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyRecruitingNCT078294971 country
- Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic DiseaseRecruitingNCT025048791 country
- Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE-FSRecruitingNCT06413914Not applicable1 country
- Testimonials and Navigation in RheumatologyRecruitingNCT06469788Not applicable1 country
- Evaluation of a Therapeutic Education Program on Self-image in Patients With Chronic Inflammatory Rheumatic DiseasesRecruitingNCT071708261 country
- Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic DiseasesRecruitingNCT07275580Phase 41 country
- Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid ArthritisRecruitingNCT07274124Not applicable1 country
- Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked PainNot yet recruitingNCT07101978Not applicable1 country
- Effectiveness of a Combined e-Learning and Virtual Reality Training Program for Healthcare Providers in RheumatologyRecruitingNCT07835256Not applicable1 country
- Observational Pharmaco-Epidemiology Research & AnalysisRecruitingNCT038138621 country
- Pain-Sleep in Rheumatic DiseaseNot yet recruitingNCT07775612Not applicable
- Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.RecruitingNCT069052881 country
- A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male ParticipantsNot yet recruitingNCT07744828Phase 11 country
- A Study of IN026 in Participants With Refractory GoutRecruitingNCT07587684Phase 11 country
- Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic DisordersRecruitingNCT07716488Not applicable1 country
- Influence of Methotrexate Discontinuation on Immunogenicity After PCV-20 Vaccine in Patients ARDsRecruitingNCT07242092Phase 41 country
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 21 country
- Autoimmune and Autoinflammatory Genetics StudyRecruitingNCT060043491 country
- Follow-up of the Systemic Lupus Erythematosus Cohort as Part of the Multidisciplinary Consultation at Brest CHRURecruitingNCT065513891 country
- EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular DiseasesRecruitingNCT070773041 country
- Network to Understand Reproductive Rheumatology RegistryEnrolling by invitationNCT069408691 country
- The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic ConditionsRecruitingNCT072786091 country
- Compassionate Care and Organization of Healthcare Services for a Successful Transition in RheumatologyRecruitingNCT074697871 country
- Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic DiseasesRecruitingNCT07490041Early Phase 11 country
- Rheumatology Patient Registry and BiorepositoryRecruitingNCT044020861 country
- Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient OutcomesEnrolling by invitationNCT05443321Not applicable1 country
- Exploring and Measuring the Impact of Steroids in Children and Young PeopleRecruitingNCT073503951 country
- Transforming Care for Individuals With Childhood-onset Systemic Lupus ErythematosusRecruitingNCT06232304Not applicable2 countries
- Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)RecruitingNCT06083090Not applicable1 country
- Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and EfficacyRecruitingNCT071500001 country
- Accuracy of CBC Derived Markers Against CRP and ESR in Detecting Active Rheumatoid Arthritis in Upper EgyptNot yet recruitingNCT07149194
- Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCorNot yet recruitingNCT07078357Phase 1/21 country
- Evaluation of Mood Disorders Under Biologics in Chronic Inflammatory Rheumatic DiseaseRecruitingNCT04817072Not applicable1 country
- Personalized Outreach for Equitable Treatment in RheumatologyNot yet recruitingNCT07022756Not applicable1 country
- Comparison of Initial Treatment for Carpal Tunnel Syndrome Related to Rheumatic Diseases: Corticosteroid Injection Versus Nighttime SplintingNot yet recruitingNCT07042282Not applicable1 country
- Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic DiseasesRecruitingNCT058072561 country
- Patients Pregnant Women With or Without Primary Antiphospholipid Antibody SyndromeRecruitingNCT057862351 country
- Calcium Pyrophosphate Deposition (CPPD) DiseaseNot yet recruitingNCT07005804Not applicable1 country
- FIBROmyalgia: Somatic Tracking and Exercise Program StudyNot yet recruitingNCT06922747Not applicable1 country
- Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic DiseasesRecruitingNCT06732674Not applicable1 country
- tDCS in Post-Acute COVID-19 Patients With SARDsRecruitingNCT04890483Not applicable1 country
- Use of Thermography for the Prevention and Diagnosis of Rheumatic FootNot yet recruitingNCT065157691 country
- Phase 1b Clinical Trial to Evaluate PEP and EUFLEXXA for Knee Osteoarthritis (KOA)Not yet recruitingNCT06463132Phase 11 country
- Validity and Reliability of the Inflammatory Arthritis Facilitators and Barriers to Physical Activity QuestionnaireNot yet recruitingNCT064607661 country
- Technological Based Rehabilitation on Individuals With Rheumatic DiseaseRecruitingNCT06385574Not applicable1 country
- Evaluation of Sarcopenia and Related Factors in Patients Diagnosed With Psoriatic ArthritisRecruitingNCT064373921 country
- Efficacy and Safety of Saussurea Involucrata Liquid Tonic in Patient With Postpartum RheumatismNot yet recruitingNCT06430307Phase 4
- Adversity and Its Association With the Development and Expression of Rheumatic DiseasesNot yet recruitingNCT06386380
- Prevalence of Abuse Among Patients With Rheumatic DiseasesRecruitingNCT062337601 country