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RecruitingNCT07626619Updated Sep 24, 2026

Translation, Cultural Adaptation, and Standardization of E-NMQ

An observational study in Musculoskeletal Diseases, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 20 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-09-24.

Sponsored by Riphah International University · Observational

From the registry’s dates

  • Started Aug 2026; still recruiting 3 months later.

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Study type
Observational
Model
Ecologic or community
Time perspective
Prospective
Enrollment
110
Ages
20 Years to 45 Years
Sex
All
01

Study summary

The primary objective of this study is to translate the Nordic Musculoskeletal (E-NMQ) Questionnaire Modified Version into Urdu following international guidelines. Presently, there exists no validated tool to comprehensively measure symptoms such as pain, stiffness and weakness in Urdu-speaking patients in Pakistan. Specifically, the widely used E-NMQ, having these three vital categories, has yet to be translated and validated for Urdu-speaking individuals with musculoskeletal disease (MSD).

Read the detailed description

To find the reliability and validity of the Urdu version of E-NMQ in patients of MSD, procedure involves following stages: E-NMQ will be adapted in Urdu and then back translated in English, then will be first tested for its content validity by using the content validity index. Then Urdu version of the E-NMQ will be pilot run; tested for its validity and reliability. In next step Urdu version of the E-NMQ will be tested for its validity and reliability in patients with MSD.

02

Conditions studied

  • Musculoskeletal Diseases

Keywords

  • Cultural Adaptation
  • Musculoskeletal Disorders
  • Reliability
  • Validity
03

In context

Musculoskeletal Diseases

752 studies on the registry are indexed under Musculoskeletal Diseases; 164 are open to participants now.

This study's planned enrollment of 110 is close to the median of 120 across 207 observational studies indexed under Musculoskeletal Diseases.

Browse Musculoskeletal Diseases studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,193 studies on the registry; 650 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 45 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

ndividuals with a condition affecting the musculoskeletal system

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age between 18 and 45 years.

    • Both male and females
    • Able to speak and read Urdu language Individuals with a condition affecting the musculoskeletal system
    • Age matched healthy individual recruited will be either the attendants/family members accompanying patients in Jinnah Hospital or employees of Riphah International University.

Exclusion criteria

Exclusion Criteria:

  • Pregnant females, inflammation, local infection, fracture, suspected tumor, Recent surgery

    • Unwilling patients
    • Cognitive impairment \& speech impairment
    • Any neurological diseases (reflex changes \& loss of sensation)
05

Study design

Observational model
Ecologic or community
Time perspective
Prospective
Enrollment
110 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Urdu version of Nordic Musculoskeletal Questionnaire (E-NMQ) for Urdu-Speaking Populations

    Urdu version of Nordic Musculoskeletal Questionnaire (E-NMQ) for Urdu-Speaking Populations

    Time frame: 6 weeks

  2. Modified Oswestry Disability Index

    As a comparator

    Time frame: 6 weeks

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Crawford JO, Berkovic D, Erwin J, Copsey SM, Davis A, Giagloglou E, Yazdani A, Hartvigsen J, Graveling R, Woolf A. Musculoskeletal health in the workplace. Best Pract Res Clin Rheumatol. 2020 Oct;34(5):101558. doi: 10.1016/j.berh.2020.101558. Epub 2020 Jul 14. PubMed 32680769 ↗
  • El-Tallawy SN, Nalamasu R, Salem GI, LeQuang JAK, Pergolizzi JV, Christo PJ. Management of Musculoskeletal Pain: An Update with Emphasis on Chronic Musculoskeletal Pain. Pain Ther. 2021 Jun;10(1):181-209. doi: 10.1007/s40122-021-00235-2. Epub 2021 Feb 11. PubMed 33575952 ↗
  • Horn CG, Jensen K, Hartvigsen J, Wekre LL, Skou ST, Folkestad L. Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study. Calcif Tissue Int. 2024 Oct;115(4):405-412. doi: 10.1007/s00223-024-01262-9. Epub 2024 Jul 27. PubMed 39066925 ↗
  • Kahraman T, Genc A, Goz E. The Nordic Musculoskeletal Questionnaire: cross-cultural adaptation into Turkish assessing its psychometric properties. Disabil Rehabil. 2016 Oct;38(21):2153-60. doi: 10.3109/09638288.2015.1114034. Epub 2016 Jan 4. PubMed 26726840 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Aug 2026 (actual). Primary completion is estimated for Oct 2026, 2 months after the start.

Of 86 non-industry observational studies under Musculoskeletal Diseases, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 60. This study's planned 2 months is below that.

Counting every sponsor, half of 107 studies reached it within 27 months; a quarter within 7 and three quarters within 74.

Musculoskeletal Diseases covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 1, 2026
First posted
Jun 4, 2026
StartActual
Aug 1, 2026
Primary completionEst.
Oct 10, 2026
CompletionEst.
Nov 1, 2026
Last update
Sep 24, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07626619
Responsible party
Sponsor
First posted
Jun 4, 2026
Start date
Aug 1, 2026
Primary completion
Oct 10, 2026 (estimated)
Completion
Nov 1, 2026 (estimated)
Last update
Sep 24, 2026

Study contacts

Imran Amjad, PhD
Contact
Imran.amjad@riphah.edu.pk
03324390125
Hira Shaukat, Mphill
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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