Drug
Hydromorphone clinical trials
Also written Dilaudid and Hydromorphon.
- studies test it
- 106
- open now
- 8
- in phase 3
- 17
- first study started
- 1996
Keep track of what changes. Save the Hydromorphone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Other names
Studies by the year they started
105 studies that test it; most in 2011 (9)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2007 | 5 |
| 2008 | 2 |
| 2009 | 5 |
| 2010 | 3 |
| 2011 | 9 |
| 2012 | 2 |
| 2013 | 9 |
| 2014 | 6 |
| 2015 | 9 |
| 2016 | 7 |
| 2017 | 4 |
| 2018 | 7 |
| 2019 | 4 |
| 2020 | 6 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 3 |
| 2024 | 3 |
| 2025 | 3 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 12
- Phase 2
- 18
- Phase 3
- 17
- Phase 4
- 41
- No phase
- 19
What it is tested for
Each study’s main condition, where its own words name it.
- Pain
- 1
Who runs them
Industry 13 · Other 93
Montefiore Medical Center (14) · Duke University (7) · Mayo Clinic (7) · University of Erlangen-Nürnberg Medical School (3) · M.D. Anderson Cancer Center (2) · University of Alberta (2) · Maternal and Child Health Hospital of Hubei Province (2) · Piramal Critical Care, Ltd. (2)
Often tested with
Tested in the same studies.
Morphine (11) · Fentanyl (10) · Methadone (6) · Sufentanil (6) · Acetaminophen (5) · Oxycodone (5) · Ketamine (4) · Bupivacaine (3)
Studies
Open first, then newest update. How each study uses Hydromorphone is read from its arms, and is right about nine times in ten.
Testing it · 106
- Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer PainRecruitingEarly Phase 1Qinghai Red Cross HospitalNCT07489625Written as Hydromorphone Hydrochloride Extended-Release Tablets
- Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate SurgeryRecruitingPhase 4Duke UniversityNCT06962306Written as Fentanyl/Hydromorphone
- Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing SurgeryRecruitingPhase 4Mayo ClinicNCT06525740Written as Hydromorphone
- Optimization of Pediatric Tonsillectomy to IMprove AnaLgesiaRecruitingPhase 4Duke UniversityNCT06576830Written as Fentanyl/Hydromorphone
- Intravenous Hydromorphone for the Treatment of Acute PainRecruitingPhase 1/2The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolNCT06949059Written as Hydromorphone
- Assessing a Clinically-meaningful Opioid Withdrawal PhenotypeRecruitingPhase 2University of Maryland, BaltimoreNCT05027919Written as Hydromorphone
- The Effects of ECMO on the Pharmacokinetics of HydromorphoneRecruitingPhase 2Xiaobo Yang, MDNCT05565495Written as Hydromorphone
- Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor AnalgesiaRecruitingPhase 2Maternal and Child Health Hospital of Hubei ProvinceNCT06036797Written as Hydromorphone
- Hydromorphone for ICU-analgesia in Patients With Non-mechanical VentilationCompletedPhase 4Nanfang Hospital, Southern Medical UniversityNCT04436224Written as Hydromorphone
- Clinical Practice of Hydromorphone in Multimodal Analgesia for Enhanced Recovery After Surgery (ERAS) in Knee ArthroplastyCompletedNot applicableChina-Japan Friendship HospitalNCT07722234Written as Hydromorphone
- Fentanyl Versus Hydromorphone in Patients on Mechanical VentilationCompletedPhase 2Beth Israel Deaconess Medical CenterNCT07224620Written as Hydromorphone
- Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver SurgeryActive, not recruitingPhase 3M.D. Anderson Cancer CenterNCT03214510Written as Hydromorphone Hydrochloride
- Satisfactory Analgesia Minimal Emesis in Day SurgeriesCompletedNot applicableMcMaster UniversityNCT02223377Written as Hydromorphone
- Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer PainActive, not recruitingPhase 4M.D. Anderson Cancer CenterNCT04296305Written as Hydromorphone
- A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis RepairTerminatedPhase 4Mayo ClinicNCT05552443Written as Hydromorphone 2.5 mcg/kg
- Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking BuprenorphineWithdrawnPhase 4University of North Carolina, Chapel HillNCT06784180Written as Hydromorphone
- Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)CompletedPhase 4Duke UniversityNCT03726268Written as Hydromorphone
- IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful TitrationCompletedPhase 3Fujian Cancer HospitalNCT04785768Written as Hydromorphone Hydrochloride Injection
- Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy SurgeryCompletedEarly Phase 1Washington University School of MedicineNCT04230681Written as Hydromorphone
- Personalized Post-Operative Pain ManagementActive, not recruitingPhase 4University of Tennessee Graduate School of MedicineNCT06669650Written as Hydromorphone
See all 106 studies that test Hydromorphone →
Given in every arm · 27 — Hydromorphone is usual care beside what is tested
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingPhase 4Northwestern UniversityNCT07840183Written as Hydromorphone
- Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following PancreatoduodenectomyRecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT06411795Written as Hydromorphone
- Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use DisorderRecruitingPhase 2University of British ColumbiaNCT04234191Written as Hydromorphone
- NSAID Use After Robotic Partial NephrectomyActive, not recruitingPhase 2University of MiamiNCT05842044Written as Hydromorphone
- Multimodal Analgesia Effect on Post Surgical PatientCompletedPhase 4University of California, DavisNCT04240626Written as Dilaudid Injectable Product
- Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)CompletedEarly Phase 1William StoopsNCT05610072Written as Hydromorphone
- Levorphanol as a Second Line Opioid in Reducing Pain in Patients With CancerTerminatedEarly Phase 1M.D. Anderson Cancer CenterNCT03579446Written as Hydromorphone
- Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).TerminatedPhase 1AstraZenecaNCT06406400Written as Hydromorphone
- ICE-T Pain Regimen for Total Laparoscopic HysterectomyCompletedPhase 4MetroHealth Medical CenterNCT03987022Written as Dilaudid Injectable Product
- Study in Subjects Undergoing Complete AbdominoplastyCompletedPhase 2Concentric AnalgesicsNCT03789318Written as Hydromorphone
- Multimodal Pain Management After Robotic-Assisted Total Laparoscopic HysterectomyCompletedPhase 3State University of New York at BuffaloNCT04429022Written as Hydromorphone
- Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell DiseaseTerminatedPhase 3Duke UniversityNCT03933397Written as Hydromorphone
- IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department PatientsCompletedPhase 3Albert Einstein College of MedicineNCT03553498Written as hydromorphone
- Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CACompletedPhase 3Stanford UniversityNCT02601027Written as Hydromorphone
- Fentanyl for Breakthrough Pain in the Emergency DepartmentTerminatedPhase 4M.D. Anderson Cancer CenterNCT01812759Written as Hydromorphone PCA
- PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer PainCompletedPhase 3Fujian Cancer HospitalNCT03375515Written as Hydromorphone
- The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine FusionTerminatedPhase 4University of Southern CaliforniaNCT03104816Written as Hydromorphone
- Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee ArthroplastyTerminatedPhase 4University of Southern CaliforniaNCT02987920Written as Hydromorphone
- Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid DisorderCompletedPhase 2Indivior Inc.NCT02044094Written as hydromorphone
- Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin)CompletedPhase 4Endo PharmaceuticalsNCT00955110Written as Hydromorphone
Showing 20 of 27.
As the comparator · 16 — what is tested is compared with Hydromorphone
- Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency DepartmentRecruitingPhase 1/2The Cooper Health SystemNCT07430345Written as Hydromorphone 0.25 mg IV
- Spinal Anesthesia For Enhanced Recovery After Liver SurgeryRecruitingNot applicableUniversity of ManitobaNCT03715517Written as Hydromorphone 10 mcg/mL epidural solution
- Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic SurgeryRecruitingPhase 4The Fourth Affiliated Hospital of Zhejiang University School of MedicineNCT06320041Written as Hydromorphone group
- The Evaluation of the Effectiveness and Safety of Nalbuphine Hydrochloride Injection for Analgesia in ICU Patients: A Multicenter, Randomized, Single-blinded, Parallel, Two-step TrialRecruitingPhase 2/3Wuhan Union Hospital, ChinaNCT06785571Written as Hydromorphone hydrochloride injection
- Reducing Pain With Methadone and Ketamine in Liver TransplantCompletedPhase 4Lahey ClinicNCT06868589Written as Hydromorphone
- High Dose IV Lidocaine vs Hydromorphone for Abdominal Pain in the Emergency DepartmentTerminatedPhase 4Hennepin Healthcare Research InstituteNCT04398316Written as HYDROmorphone Injection
- Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the EDCompletedPhase 2Montefiore Medical CenterNCT03521102Written as Hydromorphone 0.5 mg IV
- Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut SurgeryCompletedPhase 4Endeavor HealthNCT01546948Written as Hydromorphone
- Compare Fentanyl Nasal Spray With Intravenous Opioids to Treat Severe PainCompletedPhase 4M.D. Anderson Cancer CenterNCT02459964Written as Hydromorphone Hydrochloride
- Methadone and Hydromorphone For Spinal SurgeryCompletedPhase 4Endeavor HealthNCT02107339Written as Hydromorphone
- US-guided SAPB for Rib Fractures in the EDStatus unknownPhase 4Andrew A HerringNCT03619785Written as Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
- Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery PatientsCompletedEarly Phase 1Johns Hopkins UniversityNCT03088306Written as Standard analgesia use [Hydromorphone]
- Ketamine Patient-Controlled Analgesia for Acute PainTerminatedPhase 3University of CincinnatiNCT02062879Written as Hydromorphone
- Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal PainCompletedPhase 1Johns Hopkins UniversityNCT02372591Written as Hydromorphone
- Intravenous Remifentanil for Labor AnalgesiaCompletedPhase 4Nanjing Medical UniversityNCT00710086Written as Hydromorphone
- Effects of Intravenous Local Anesthetic on Bowel Function After ColectomyCompletedPhase 3University of VirginiaNCT00600158Written as bupivacaine with hydromorphone
Codes
What other systems call Hydromorphone · ClinicalTrials.gg INT007357
- MeSH (NLM) D004091HydromorphoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Q812464R06HYDROMORPHONEConfirmed FDA, NLM, Wikidata
- RxNorm 3423Confirmed FDA, Wikidata
- Wikidata Q303646hydromorphoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62034HydromorphoneOne source FDA
- DrugBank DB00327One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004091 | Hydromorphone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Q812464R06 | HYDROMORPHONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3423 | — | Confirmed FDA, Wikidata |
| Wikidata | Q303646 | hydromorphone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62034 | Hydromorphone | One source FDA |
| DrugBank | DB00327 | — | One source Wikidata |
Also registered as hydromorphone hydrochloride (UNII L960UP2KRW · RxNorm 203177).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.