Labor Pain clinical trials
The registry lists 423 studies for Labor Pain across more than 10 countries. 74 are recruiting or about to start. 395 of them are mainly about Labor Pain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Samuel Lunenfeld Research Institute, Mount Sinai Hospital (22) · Ataturk University (10) · Istanbul University - Cerrahpasa (10) · Northwestern University (9) · Nanjing Medical University (7) · Selcuk University (7) · Stanford University (6) · Ain Shams University (6)
What is being tested here
Drugs under test in Labor Pain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bupivacaine | 2 | 2 | 17 |
| Ropivacaine | 2 | 1 | 6 |
| Fentanyl | 1 | 1 | 12 |
| Acetaminophen | 1 | 2 | 6 |
| Dexmedetomidine | 1 | 1 | 5 |
| Morphine | 1 | 1 | 4 |
| Hydromorphone | 1 | 0 | 3 |
| Nalbuphine | 1 | 0 | 2 |
| Tramadol | 1 | 0 | 1 |
| Papaverine | 1 | 0 | 1 |
Drug classes tested here Opioids 4 open · Local anesthetics 4 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026The Use of Electrical Stimulation for Determination of Epidural Catheter Placement · Stanford University
- Nov 2026Using Wet Towel During Labor · Sakarya University
- Nov 2026Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Nov 2026Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor · Universidad Nacional Autonoma de Honduras
- Dec 2026Storytelling for Provider Empathy & Patient Trust in Obstetric Care · Duke University
- Dec 2026Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population · Stanford University
- Dec 2026Neuraxial Labor Analgesia and Offspring Neurodevelopment · Dong-Xin Wang
- Dec 2026Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural · Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Dec 2026Pain Science Education for Labour and Postpartum Pain · Bournemouth University
- Dec 2026The Effect of Hand Exercise Hoops on Labour Pain · Istanbul University - Cerrahpasa
Who these studies take
Of the 30 Labor Pain studies recruiting now, 8 (27%) set no upper age limit and 22 (73%) stop at 75 or younger. 3 (10%) take children under 18. 29 (97%) are for women only and 0 (0%) for men only; 20 (67%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (3%) | 0 (0%) |
| 18 | 28 (93%) | 0 (0%) |
| 30 | 29 (97%) | 0 (0%) |
| 40 | 25 (83%) | 0 (0%) |
| 50 | 14 (47%) | 0 (0%) |
| 65 | 8 (27%) | 0 (0%) |
| 75 | 8 (27%) | 0 (0%) |
| 85 | 8 (27%) | 0 (0%) |
Across all 423 studies, recruiting or not: 73% stop at 75 or younger and 73% at 65; 10% take children; 98% are for women only and 0% for men only; 61% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Labor Pain studies take
Of 20 phase 4 interventional studies under Labor Pain, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 28 mo11–… · 20 studies | — | — |
| Interventional, no phase | 9 mo5–14 · 193 studies | — | 9 mo5–14 · 191 studies |
| Observational | 9 mo6–32 · 31 studies | — | 9 mo6–32 · 30 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered6
- Effect of Epidural Analgesia Timing on Labor Duration and Obstetric OutcomesNov 10, 2026NCT07929376
- Pain Neuroscience-Based Education for Labor Pain in Pregnant WomenOct 29, 2026NCT07902947
- Effect of Birth Dance on Birth BeliefsOct 29, 2026NCT07903363
- The 90% Effective Initial Volume for Labor Analgesia Under Double Dural Puncture Epidural TechniqueOct 26, 2026NCT07894770
- Initiation Ropivacaine Dose for Labor Analgesia Via Double Dural Puncture Epidural TechniqueOct 20, 2026NCT07882004
Show 1 moreShow fewer
- Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late LaborOct 14, 2026NCT07873814
Studies
Recruiting first, then most recently updated. Showing 50 of 423. Browse all 423 → or search them.
- The Effect Of Partner-Assısted Rebozo Technıque On Labor Paın And Satısfactıon In Prımary Pregnant WomenRecruitingNCT07752693Not applicable1 country
- Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active LaborRecruitingNCT07440069Phase 41 country
- Pain Neuroscience-Based Education for Labor Pain in Pregnant WomenRecruitingNCT07902947Not applicable1 country
- The 90% Effective Initial Volume for Labor Analgesia Under Double Dural Puncture Epidural TechniqueNot yet recruitingNCT07894770Not applicable
- Initiation Ropivacaine Dose for Labor Analgesia Via Double Dural Puncture Epidural TechniqueNot yet recruitingNCT07882004Not applicable
- Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late LaborNot yet recruitingNCT078738141 country
- THE EFFECT OF LISTENING TO SURAH ABESE (VERSES 19-20) DURING CHILDBIRTH ON VAGINAL BIRTH SELF-EFFICACY, BIRTH BELIEFS, AND PAIN PERCEPTIONNot yet recruitingNCT07865637Not applicable
- A Digital Educational Resource to Improve Preparedness for Shared Decision Making About Labour AnalgesiaRecruitingNCT07516171Not applicable1 country
- Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound InfiltrationNot yet recruitingNCT078599561 country
- Does the Volume of Medication Affect the Success of Labor Epidural AnalgesiaNot yet recruitingNCT07684365Phase 4
- Pain Selective Anesthesia for Labor Mobility (PSALM Study): a Randomized Controlled Trial of Combined Lidocaine - Chlorprocaine for Labor Epidural AnalgesiaRecruitingNCT06302257Phase 41 country
- The Effects of Innatal Yoga Practices on Pain, Comfort, and Satisfaction in Primiparous WomenNot yet recruitingNCT07839962Not applicable1 country
- Postpartum Effects of Mirror Therapy During LaborRecruitingNCT07792629Not applicable1 country
- Storytelling for Provider Empathy & Patient Trust in Obstetric CareNot yet recruitingNCT07588308Not applicable
- Two Different Sized Spinal Needles DPE vs Conventional Epidural TechniqueNot yet recruitingNCT07708909Not applicable
- Dural Puncture Epidural (DPE) Technique: Efficacy and Safety Overview.RecruitingNCT077045541 country
- ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPLRecruitingNCT06146842Phase 41 country
- ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor AnalgesiaRecruitingNCT05543694Phase 41 country
- USE OF PERINEAL MIRROR DURING THE SECOND STAGE OF LABORNot yet recruitingNCT07659249Not applicable1 country
- Neuraxial Labor Analgesia and Offspring NeurodevelopmentRecruitingNCT049642061 country
- Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal DeliveryNot yet recruitingNCT075822891 country
- Effects of Midwife-guided biırth Affirmation Cards on Labor Process and Experience ın PrimigravidasRecruitingNCT07542392Not applicable1 country
- Neuraxial Ultrasound Device StudyNot yet recruitingNCT06281249Not applicable1 country
- Pain Science Education for Labour and Postpartum PainEnrolling by invitationNCT070966611 country
- Continuous Remote Vital Sign Monitoring During Labour Analgesia With RemifentanilNot yet recruitingNCT071674981 country
- Effectiveness of Sacral Massage on Labor Pain, Depression, Stress, and AnxietyNot yet recruitingNCT07501598Not applicable
- Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal EpiduralRecruitingNCT06572241Not applicable1 country
- Induction of Labor by Cervical Ripening and Transcutaneous Electrical Nerve Stimulation (TENS)Not yet recruitingNCT07494539Not applicable
- Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean DeliveryRecruitingNCT06355271Not applicable1 country
- The Effect of the World Health Organisation-Based Intrapartum Care Model on Labour Pain, Comfort, Satisfaction and Postpartum DepressionNot yet recruitingNCT07451691Not applicable1 country
- Labour Pain Relief Options: Video Versus Pamphlet for Easing Fear of Birth and Improving Preparedness in Pregnant Patients, an RCTNot yet recruitingNCT07437703Not applicable
- Left Lateral Position vs Supine Position to Reduce Active Labor DurationRecruitingNCT07411352Not applicable1 country
- Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor.RecruitingNCT07401147Not applicable1 country
- Comparing PIEB and CEI for Labor Pain ReliefRecruitingNCT07395934Not applicable1 country
- The Effect of Hand Exercise Hoops on Labour PainNot yet recruitingNCT07378449Not applicable1 country
- Sacral Pressure During Labor: Effects on Pain and Maternal SatisfactionNot yet recruitingNCT07371039Not applicable
- The Effect of Skin-to-Skin Contact Applied in the Early Postpartum Period on Maternal Pain, Birth Satisfaction, and Maternal Vital Signs DynamicsEnrolling by invitationNCT07304037Not applicable1 country
- Effect of Multi-Sensory Interventions on Labor Pain, Comfort, and Birth SatisfactionNot yet recruitingNCT07248787Not applicable1 country
- Spoken Animation for Labour EpiduralNot yet recruitingNCT07202221Not applicable1 country
- Virtual Reality for Pain and Anxiety Relief in LaborEnrolling by invitationNCT07194967Not applicable1 country
- Music Therapy for Labor Pain and AnxietyNot yet recruitingNCT07139574Not applicable1 country
- Can Labor Pain be Reduced by Open Placebo Intervention? A Bayesian Account for Labor PainNot yet recruitingNCT07077590Not applicable1 country
- Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women (PART II)RecruitingNCT06655675Not applicable1 country
- Effects of Rosa Damascena and Frankincense Essential Oils in LaborRecruitingNCT06189794Not applicable1 country
- Pain Management With Virtual Reality HypnosisRecruitingNCT06502457Not applicable1 country
- Sacral Massage With a Tennis Ball on Labor Pain and Comfort During the Intrapartum PeriodNot yet recruitingNCT06898580Not applicable
- Obstetric Placement Study Using ESTRecruitingNCT04109365Not applicable1 country
- Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric PopulationNot yet recruitingNCT04983511Not applicable
- The Use of Electrical Stimulation for Determination of Epidural Catheter PlacementNot yet recruitingNCT06055686Not applicable1 country
- Effect of Foot Reflexology on Postpartum AfterpainsNot yet recruitingNCT06951750Not applicable1 country