Hydromorphone: all 106 studies that test it

Page 1 of 2. Open to participants first (8), then studies with results posted, then the rest; newest registration first within each.

• Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer PainRecruitingNCT07489625Early Phase 1
• Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate SurgeryRecruitingNCT06962306Phase 4
• Intravenous Hydromorphone for the Treatment of Acute PainRecruitingNCT06949059Phase 1/2
• Optimization of Pediatric Tonsillectomy to IMprove AnaLgesiaRecruitingNCT06576830Phase 4
• Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing SurgeryRecruitingNCT06525740Phase 4
• Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor AnalgesiaRecruitingNCT06036797Phase 2
• The Effects of ECMO on the Pharmacokinetics of HydromorphoneRecruitingNCT05565495Phase 2
• Assessing a Clinically-meaningful Opioid Withdrawal PhenotypeRecruitingNCT05027919Phase 2
• A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis RepairTerminatedNCT05552443Phase 4Results posted
• Pediatric Pain Optimization After TonsillectomyCompletedNCT05244226Phase 2Results posted
• Intrathecal Opioids for Colorectal ResectionCompletedNCT04752033Phase 4Results posted
• Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological MalignanciesCompletedNCT04258631Phase 4Results posted
• Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy SurgeryCompletedNCT04230681Early Phase 1Results posted
• Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)CompletedNCT03726268Phase 4Results posted
• Intravenous Lidocaine Randomized Comparative Effectiveness TrialCompletedNCT03300674Phase 4Results posted
• Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean DeliveryCompletedNCT02789410Not applicableResults posted
• Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
• IV Acetaminophen as an Analgesic AdjunctCompletedNCT02621619Phase 4Results posted
• Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.CompletedNCT02437669Phase 2Results posted
• Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute MigraineCompletedNCT02389829Phase 4Results posted
• Exparel Transversus Abdominis Plane Block vs Intrathecal Analgesia In Colorectal SurgeryCompletedNCT02356198Not applicableResults posted
• Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain PatientsTerminatedNCT02321319Phase 3Results posted
• Satisfactory Analgesia Minimal Emesis in Day SurgeriesCompletedNCT02223377Not applicableResults posted
• Comparing Acute Pain Management Protocols for Patients With Sickle Cell DiseaseCompletedNCT02222246Phase 4Results posted
• The Effects of Hydromorphone on Responses to Verbal TasksCompletedNCT02205983Not applicableResults posted
• Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic ColectomyTerminatedNCT02164929Not applicableResults posted
• Intrathecal Hydromorphone for Pain Control After Cesarean SectionCompletedNCT02096003Phase 2Results posted
• A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum RepairTerminatedNCT02056301Phase 4Results posted
• Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal DoseCompletedNCT02009722Phase 4Results posted
• Epidural Analgesia Versus IV Analgesia in Lumbar Spine FusionsTerminatedNCT01986946Phase 3Results posted
• Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding StudyTerminatedNCT01943565Phase 4Results posted
• Titration of Intravenous HydromorphoneCompletedNCT01892709Phase 4Results posted
• Study of Respiratory Depression When Using a Hydromorphone Pain ProtocolTerminatedNCT01784991Not applicableResults posted
• Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal AdministrationCompletedNCT01709747Phase 3Results posted
• Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal AdministrationCompletedNCT01709721Phase 3Results posted
• Association Between Body Size and Response to Hydromorphone in EDCompletedNCT01675778Phase 2Results posted
• Hydromorphone and C-sectionCompletedNCT01598545Phase 2Results posted
• Intrathecal Hydromorphone for Labor AnalgesiaCompletedNCT01598506Phase 2Results posted
• True Functional Restoration and Analgesia in Non-Radicular Low Back PainCompletedNCT01455519Phase 4Results posted
• Comparing Intravenous Hydromorphone to Usual CareCompletedNCT01429298Phase 4Results posted
• Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe PainCompletedNCT01429285Phase 4Results posted
• Clinical Trial Comparing Two Protocols Using Intravenous (IV) HydromorphoneCompletedNCT01311895Phase 3Results posted
• Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic PainCompletedNCT01207596Phase 4Results posted
• An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related PainCompletedNCT01205126Phase 3Results posted
• Protocolized vs Discretionary Use of Opioids in Acute PainCompletedNCT00825370Phase 3Results posted
• An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer PainCompletedNCT00766831Phase 4Results posted
• Safety Study of Intravenous Hydromorphone Using Incremental 1mg Doses up to 2mg for Adult ED PatientsCompletedNCT00682435Phase 4Results posted
• Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe PainCompletedNCT00627367Phase 3Results posted
• The Discriminative Effects of Tramadol in HumansCompletedNCT00499746Phase 1/2Results posted
• An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative PainCompletedNCT00465647Phase 4Results posted
• Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)CompletedNCT00385541Phase 4Results posted
• Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe PainCompletedNCT00305110Phase 2Results posted
• Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe PainCompletedNCT00305058Phase 2/3Results posted
• Clinical Practice of Hydromorphone in Multimodal Analgesia for Enhanced Recovery After Surgery (ERAS) in Knee ArthroplastyCompletedNCT07722234Not applicable
• Fentanyl Versus Hydromorphone in Patients on Mechanical VentilationCompletedNCT07224620Phase 2
• Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking BuprenorphineWithdrawnNCT06784180Phase 4
• Personalized Post-Operative Pain ManagementActive, not recruitingNCT06669650Phase 4
• Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor AnalgesiaCompletedNCT05901441Phase 2
• Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel ControlledStatus unknownNCT05848635Phase 4
• Patient-controlled Intravenous Analgesia Combined With Different Opioid Receptors for Gastrointestinal SurgeryCompletedNCT05576675Phase 3
• Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic SurgeriesCompletedNCT05375916Not applicable
• IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful TitrationCompletedNCT04785768Phase 3
• The Effect of Esketamine on Patients Undergoing Tumor SurgeryStatus unknownNCT04613869Not applicable
• Hydromorphone for ICU-analgesia in Patients With Non-mechanical VentilationCompletedNCT04436224Phase 4
• Non-analgesic Effects Produced by Equipotent Analgesic Doses of Sufentanil, Hydromorphone, and OxycodoneCompletedNCT04396587Phase 4
• Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer PainActive, not recruitingNCT04296305Phase 4
• the Effect of Different Drugs and Infusion Ways on Degree of Postoperative ComfortCompletedNCT04111328Phase 4
• Generation of Biological Samples Positive to Hydromorphone for Anti-doping ControlCompletedNCT04081376Phase 1
• Acute Pain Management in Patients on Opioid Replacement TherapyTerminatedNCT03933865Phase 1
• A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure Which Aims to Evaluate Whether GRT0151Y is Likely to be AbusedCompletedNCT03768024Phase 1
• Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal InjuriesCompletedNCT03767933Phase 2
• Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted ThoracoscopyCompletedNCT03648008Phase 4
• Pain Management After Elective Shoulder SurgeryCompletedNCT03541759Phase 4
• Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the EDTerminatedNCT03478423Not applicable
• TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean AnalgesiaWithdrawnNCT03282669Phase 4
• Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver SurgeryActive, not recruitingNCT03214510Phase 3
• Acetaminophen IV vs Hydromorphone IV in the EDCompletedNCT03107481Phase 4
• Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene BlockCompletedNCT02939209Phase 4
• Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?Status unknownNCT02880800Not applicable
• Pain Medications in Children Undergoing Strabismus SurgeryStatus unknownNCT02789969Not applicable
• Dose and Response of Intrathecal Hydromorphone in Patients Undergoing Cesarean Section at Virginia Commonwealth University Health SystemTerminatedNCT02787928Phase 1
• Neuraxial Ultrasound for Thoracic Epidural PlacementCompletedNCT02785055Not applicable
• Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCACompletedNCT02483221Phase 4
• Synergistic Effect of Ibuprofen and Hydromorphone for Postoperative PainCompletedNCT02461056Not applicable
• Post-tonsillectomy Pain Control in AdultsTerminatedNCT02358850Phase 4
• Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement SurgeryCompletedNCT02295124Phase 4
• Intrathecal Hydromorphone for Labor AnalgesiaTerminatedNCT02277782Not applicable
• Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer PainStatus unknownNCT02084355Phase 3
• Intrathecal Hydromorphone for Cesarean SectionCompletedNCT02067520Phase 4
• Postoperative Pain Therapy With Hydromorphone Using TCI-PCACompletedNCT02035709Phase 4
• Use of Intrathecal Hydromorphone in Elective Cesarean DeliveriesCompletedNCT01866254Early Phase 1
• A Pharmacokinetic and Safety Study of Osmotic Release Oral System (OROS) Hydromorphone in Non-Opioid Tolerant Chinese Participants With CancerCompletedNCT01824524Phase 1
• Pain Therapy After Elective Cardiac SurgeryCompletedNCT01490268Phase 4
• Pharmacokinetic Profile of OROS Hydromorphone in Healthy Taiwanese Participants With Different Genotypes for the UGT2B7 GeneCompletedNCT01487564Phase 1
• Effect of Dose on the Pharmacokinetics of OROS Hydromorphone Under Fasted Conditions in Healthy Taiwanese ParticipantsCompletedNCT01487512Phase 1
• Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)CompletedNCT01447212Phase 3
• Patient Satisfaction and Pain Control Following Reconstructive Vaginal SurgeryCompletedNCT01442818Not applicable
• The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal AnesthesiaCompletedNCT01172782Not applicable
• Hydromorphone Pharmacokinetic-Pharmacodynamic FingerprintWithdrawnNCT01123486Not applicable
• Fasting Study of Hydromorphone Hydrochloride 8 mg Tablets and Dilaudid 8 mg TabletsCompletedNCT00853554Phase 1

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