Duke University clinical trials
Listed in the registry as: University, hospital or other organization.
The registry lists 2,058 studies whose lead sponsor is Duke University. 274 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 23, 2026.
Keep track of what changes. Save the Duke University studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
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Focus areas
Conditions Duke University leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Heart Failure55Breast Neoplasms54Depression53Prostatic Neoplasms42Glioma39Hypertension39Cardiovascular Diseases37Glioblastoma37COVID-1936Obesity36Brain Neoplasms31Central Nervous System Neoplasms30Neoplasms30Diabetes Mellitus28Anemia, Sickle Cell27Diabetes Mellitus, Type 226Tobacco Use Disorder26Depressive Disorder25Osteoarthritis25Stress Disorders, Post-Traumatic24Heart Diseases22Lung Neoplasms21Renal Insufficiency, Chronic21Pediatric Obesity20
Show all 67 areas
Carcinoma, Non-Small-Cell Lung19Cognitive Dysfunction19Kidney Diseases19Pain19Stroke18Gliosarcoma17Infections17Pain, Postoperative17Uterine Cervical Neoplasms17Dementia16Glaucoma16Alzheimer Disease15Arthritis15Carcinoma, Renal Cell15Chronic Pain15Parkinson Disease15Wounds and Injuries15Attention Deficit Disorder with Hyperactivity14Feeding and Eating Disorders14Hematologic Neoplasms14Glycogen Storage Disease Type II13Lupus Erythematosus, Systemic13Melanoma13Asthma12HIV Infections12Lymphoma12Premature Birth12Arthritis, Rheumatoid11Brain Injuries, Traumatic11Macular Degeneration11Malaria11Osteoarthritis, Knee11Pulmonary Disease, Chronic Obstructive11Sleep Initiation and Maintenance Disorders11Atrial Fibrillation10Brain Injuries10Colorectal Neoplasms10Coronary Artery Disease10Coronary Disease10Leukemia10Retinal Diseases10Sepsis10Substance-Related Disorders10
Studies
Recruiting first, then most recently updated. Showing 50 of 2,058. Browse all 2,058 →
- Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionRecruitingNCT06909565Phase 4
- Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma PatientsRecruitingNCT04933435Not applicable
- Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic ArthritisRecruitingNCT06654882Phase 3
- Observational Study of Pediatric Rheumatic Diseases: The CARRA RegistryRecruitingNCT02418442
- Oxygen Toxicity: Mechanisms in HumansRecruitingNCT05761756Not applicable
- Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-dailyRecruitingNCT07425119Not applicable
- Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain TumorsRecruitingNCT05480644
- Intraoperative OCT Guidance of Intraocular Surgery IIRecruitingNCT03713268
- Imaging Retinal Vasculature in Infant EyesRecruitingNCT05558059
- Sleep-Sensitive Seizure Risk Assessment With Wearable EEGsRecruitingNCT06545643Not applicable
- 4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800RecruitingNCT07024719Not applicable
- Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEPRecruitingNCT07218211Phase 4
- Exparel and DexamethasoneNot yet recruitingNCT07614802Phase 4
- Effect of Periumbilical Vibration on Pain Perception During Intrauterine Device Insertion: A Randomized Controlled TrialRecruitingNCT07714590Not applicable
- Lupus Nephritis Care PathwayRecruitingNCT07783152Not applicable
- TOP 2301: Neoadjuvant Chemo for NSCLCRecruitingNCT06385262Phase 2
- Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)RecruitingNCT05055830
- Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?RecruitingNCT06471036Not applicable
- SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino FamiliesRecruitingNCT06627764Not applicable
- Prognostic Value of Clinical Cardiovascular MRIRecruitingNCT01745237
- Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal PainNot yet recruitingNCT06987786Not applicable
- Overnight TI in TLERecruitingNCT07434986Not applicable
- Weight Management After Cancer for Survivors in Rural CommunitiesRecruitingNCT07426952Not applicable
- Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus BlockRecruitingNCT04209504
- Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort StudyRecruitingNCT06604650
- Ultrasound Imaging of the Head, Neck, and AirwayRecruitingNCT07406061
- Combating Related Epidemics in HCVNot yet recruitingNCT07560046Phase 4
- IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron DeficiencyNot yet recruitingNCT07686692Phase 4
- Temporal Interference Brain Stimulation for Adults With Drug-Resistant Epilepsy Undergoing Stereo-EEG MonitoringRecruitingNCT07764718Not applicable
- IMPRoving Outcomes in Vascular DisEase - Aortic DissectionRecruitingNCT06087029Not applicable
- Chronic Exogenous Ketosis in HFpEFEnrolling by invitationNCT06937320Phase 2
- The Comparative Effectiveness Evaluation of the Impact of Digital EducationNot yet recruitingNCT06979310Not applicable
- IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in TanzaniaNot yet recruitingNCT07459218Not applicable
- Enhancing Resilience Among Patients With Stroke: Implementation of High Intensity Home-based RehabilitationEnrolling by invitationNCT07098286
- The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services StudyNot yet recruitingNCT07216963Not applicable
- Biomarker Testing to Predict Radiation-Related Heart Disease in Lung Cancer PatientsNot yet recruitingNCT07869329Not applicable
- PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosisRecruitingNCT07232069Phase 3
- FlexED: National SubstudyRecruitingNCT07807774Not applicable
- DBT-P Treatment StudyRecruitingNCT06963801Not applicable
- Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2RecruitingNCT06139458Not applicable
- NASA Exercise Prebreathe StudyRecruitingNCT07702539Not applicable
- Optimizing PreTerm Infant Ampicillin DosingRecruitingNCT07610486Phase 1/2
- Feasibility of a Dyadic Music-based Intervention for Persons Living With Dementia and Their Care PartnersNot yet recruitingNCT07843043Not applicable
- Vaginal Dose De-escalation During Brachytherapy for Cervical CancerNot yet recruitingNCT07855263Not applicable
- Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural AmericaRecruitingNCT06229418Not applicable
- Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)RecruitingNCT06906627Not applicable
- Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)RecruitingNCT06906640Not applicable
- Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral SuppressionNot yet recruitingNCT05459077Not applicable
- Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed CancerNot yet recruitingNCT07811258Not applicable
- Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal AdenocarcinomaRecruitingNCT07603375Phase 2