Chronic Pain clinical trials

The registry lists 3,227 studies for Chronic Pain across more than 10 countries. 729 are recruiting or about to start. 1,901 of them are mainly about Chronic Pain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 7,899 studies for Chronic Pain. How that becomes 3,224 here

This page counts the studies the registry files under Chronic Pain, and those it files under no condition that list Chronic Painthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

7,899Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
−259List Chronic Pain as a condition, but the registry did not file them under itMost often written as “Knee Pain Chronic” (95), “Hip Pain Chronic” (26), and “Chronic Pain Syndrome” (23). The registry filed them under other conditions only, most often Osteoarthritis, Knee (63) and Pain, Postoperative (46).
−4,416Match it another way460 name it in the title, 39 in a keyword, and 3,917 by a synonym or other text the search reads.
3,224The count on this page102 of them list Chronic Pain in their own words; the registry filed them under no condition.

Get an email when these change. Save the Chronic Pain studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

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Status

Completed: 1,790
Recruiting: 486
Status unknown: 304
Not yet recruiting: 197
Active, not recruiting: 161
Terminated: 142

Phase

Phase 2: 189
Phase 3: 159
Phase 4: 125
Phase 1: 112
Early Phase 1: 27

Where

United States: 1,283
Turkey: 203
Canada: 202
Spain: 174
France: 135
United Kingdom: 116

Who runs them

VA Office of Research and Development (57) · Stanford University (47) · University of Washington (39) · Boston Scientific Corporation (33) · University of Michigan (29) · University of Utah (28) · Assiut University (27) · Massachusetts General Hospital (27)

What is being tested here

Drugs under test in Chronic Pain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Adezunap	7	7	7
Psilocybin	5	0	6
Ketamine	4	7	31
Cannabidiol	4	1	11
Dexamethasone	4	0	7
Lidocaine	3	5	23
Dexmedetomidine	2	0	10
Tramadol	2	8	10
Dronabinol	2	1	8
Diclofenac	2	0	2

Drug classes tested here Opioids 7 open · Psychedelics 6 open · Local anesthetics 5 open · Serotonin receptor agonists 5 open · Corticosteroids 4 open

Coming up

24phase 3 studies under way

291studies finish main data collection within a year5 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Nov 2026Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia · Phase 3 · Northwestern University
Jan 2027Clinical Analgesic Management in Dementia · Phase 3 · Xuanwu Hospital, Beijing
Feb 2027Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches · Phase 3 · University Health Network, Toronto
May 2027Tele-Collaborative Outreach to Rural Patients With Chronic Pain · Phase 3 · Oregon Health and Science University
Jun 2027Divided or Single Exposure (DOSE) Study · Phase 3 · University of Maryland, Baltimore
Nov 2026PEACE: Comparing Chronic Pain Treatment Options · Memorial Sloan Kettering Cancer Center
Nov 2026PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product · Staci Gruber, Ph.D.
Nov 2026Targeted Realtime Assessment of Chronic Pain in Youth · Stanford University
Nov 2026Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression · Stanford University
Nov 2026Pilot Study of Robotic Spinal Mobilization in Parkinson's Disease · Pacla Medical Limited

Who these studies take

Of the 486 Chronic Pain studies recruiting now, 239 (49%) set no upper age limit and 173 (36%) stop at 75 or younger. 43 (9%) take children under 18. 31 (6%) are for women only and 3 (1%) for men only; 64 (13%) take healthy volunteers.

Recruiting studies that take each age, of 486
Age	Women	Men
10	20 (4%)	21 (4%)
18	387 (80%)	368 (76%)
30	414 (85%)	387 (80%)
40	422 (87%)	394 (81%)
50	425 (87%)	400 (82%)
65	432 (89%)	408 (84%)
75	343 (71%)	332 (68%)
85	273 (56%)	266 (55%)

Across all 3,227 studies, recruiting or not: 38% stop at 75 or younger and 26% at 65; 8% take children; 8% are for women only and 2% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Chronic Pain studies take

Of 61 phase 1 interventional studies under Chronic Pain, half reached primary completion within 12 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Phase 1	12 mo6–56 · 61 studies	6 mo3–12 · 27 studies	—
Phase 2	37 mo21–52 · 61 studies	—	42 mo25–52 · 48 studies
Phase 3	37 mo22–56 · 48 studies	—	—
Phase 4	24 mo14–38 · 52 studies	—	23 mo14–40 · 50 studies
Interventional, no phase	20 mo9–38 · 1,378 studies	21 mo10–30 · 83 studies	20 mo9–39 · 1,295 studies
Observational	24 mo12–56 · 362 studies	—	24 mo11–56 · 336 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out