Tonsillitis clinical trials
The registry lists 103 studies for Tonsillitis across more than 10 countries. 12 are recruiting or about to start. 83 of them are mainly about Tonsillitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.
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Who runs them
Pfizer (4) · Sanofi (3) · Bayer (3) · Oulu University Hospital (3) · Nationwide Children's Hospital (2) · Advancis Pharmaceutical Corporation (2) · Turku University Hospital (2) · Selcuk University (2)
What is being tested here
Drugs under test in Tonsillitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Hydromorphone | 1 | 0 | 3 |
| Fentanyl | 1 | 0 | 3 |
| Methadone | 1 | 0 | 2 |
| Gabapentin | 1 | 0 | 1 |
| Dexmedetomidine | 0 | 0 | 5 |
| Acetaminophen | 0 | 0 | 4 |
| Azithromycin | 0 | 2 | 4 |
| Dexamethasone | 0 | 0 | 2 |
| Aspirin | 0 | 1 | 2 |
| Probiotic | 0 | 0 | 2 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Nov 2026Perspectives on Antibiotics and Tracking Symptoms in Children · Murdoch Childrens Research Institute
- Nov 2026SUPRATHEL 250 as a Treatment for Oropharyngeal Wounds · Alaa Emara
- Dec 2026Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy · Loma Linda University
- Jun 2027Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy · Duzce University
- Jun 2027Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis · Tejs Ehlers Klug
- Jun 2027Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Who these studies take
Of the 10 Tonsillitis studies recruiting now, 3 (30%) set no upper age limit and 6 (60%) stop at 75 or younger. 8 (80%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (60%) | 6 (60%) |
| 18 | 5 (50%) | 5 (50%) |
| 30 | 4 (40%) | 4 (40%) |
| 40 | 4 (40%) | 4 (40%) |
| 50 | 4 (40%) | 4 (40%) |
| 65 | 4 (40%) | 4 (40%) |
| 75 | 4 (40%) | 4 (40%) |
| 85 | 4 (40%) | 4 (40%) |
Across all 103 studies, recruiting or not: 72% stop at 75 or younger and 70% at 65; 80% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tonsillitis studies take
Of 29 interventional studies with no phase under Tonsillitis, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo10–49 · 29 studies | — | 20 mo10–49 · 29 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 103. Browse all 103 → or search them.
- Perspectives on Antibiotics and Tracking Symptoms in ChildrenRecruitingNCT07093749Not applicable1 country
- Suprazygomatic Maxillary Nerve Block in Pediatric TonsillectomyRecruitingNCT07176533Not applicable1 country
- Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar AbscessRecruitingNCT07577232Not applicable1 country
- SUPRATHEL 250 as a Treatment for Oropharyngeal WoundsRecruitingNCT06543823Not applicable1 country
- Recovery From Tonsil Surgery.Not yet recruitingNCT07598201Not applicable
- Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil DisordersRecruitingNCT056563651 country
- Lateral Pharyngoplasty Outcomes in Children Undergoing TonsillectomyRecruitingNCT05575401Not applicable1 country
- Optimization of Pediatric Tonsillectomy to IMprove AnaLgesiaRecruitingNCT06576830Phase 41 country
- The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.RecruitingNCT07035314Not applicable1 country
- Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic TreatmentRecruitingNCT04083417Phase 41 country
- Study on the Efficacy and Safety of a Device for Post-op Recovery in Pediatric Adenectomy/Adenotonsillectomy.Not yet recruitingNCT06478433Not applicable
- Gabapentin Premedication to Reduce Postoperative Pain for Pediatric TonsillectomyRecruitingNCT03625011Phase 41 country
- Adult Tonsillectomy Techniques: Blunt Dissection Vs Bipolar RadiofrequencyCompletedNCT07903233Not applicable1 country
- Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute TonsillitisActive, not recruitingNCT06606262Not applicable1 country
- Evaluation of the Efficacy of Streptococcus Salivarius Evol12® in the Reduction of Recurrent Adenotonsillitis in ChildrenCompletedNCT07235826Not applicable1 country
- Heart Rate Variability and Early Cytokine Profile in Pediatric AdenotonsillectomyActive, not recruitingNCT077194391 country
- Comparing Two Agents Used to Stop Bleeding During Tonsil Removal Surgery: Adrenaline Versus Hydrogen PeroxideCompletedNCT07675278Not applicable1 country
- Study Comparing Harmonic Scalpel and Conventional Cold Steel Tonsil Removal Surgery in Children Requiring TonsillectomyCompletedNCT07656831Not applicable1 country
- Coblation Tonsillotomy Versus Radiofrequency and Cold Knife Dissection TonsillectomyCompletedNCT06937762Not applicable1 country
- Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil SurgeryCompletedNCT06326983Not applicable1 country
- Coblation Tonsillectomy Versus Cold Dissection TonsillectomyCompletedNCT07457619Not applicable1 country
- Steroids and Pain Control After TonsillectomyCompletedNCT03995628Phase 21 country
- A Comparative Study of Monopolar Versus Bipolar Electrocautery Post Tonsillectomy Outcomes.Active, not recruitingNCT072655311 country
- Intracapsular Tonsillectomy in AdultsActive, not recruitingNCT03654742Not applicable1 country
- Bacteriophage Therapy in TonsillitisActive, not recruitingNCT04682964Phase 31 country
- Opioid-Free Anesthetic for TonsillectomyTerminatedNCT04528173Phase 41 country
- Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy SurgeryCompletedNCT04230681Early Phase 11 country
- Pediatric Pain Optimization After TonsillectomyCompletedNCT05244226Phase 21 country
- Management of Post-Tonsillectomy Pain in Pediatric PatientsCompletedNCT04551196Phase 31 country
- Outcomes of Bipolar Electrocautery Tonsillectomy Versus Cold Steel Dissection Pediatric TonsillectomyCompletedNCT06494839Not applicable1 country
- Immune Response To Intranasal Influenza VaccinationActive, not recruitingNCT01866540Not applicable1 country
- Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common ColdCompletedNCT01361399Phase 32 countries
- Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract InfectionsTerminatedNCT05279534Not applicable1 country
- Tonsil Surgery in Recurrent or Chronic TonsillitisCompletedNCT04657549Not applicable1 country
- Vitamin D Levels in Children Undergoing Adenotonsillectomies and ControlsCompletedNCT008299721 country
- Improving the Diagnosis of Tonsillitis in Emergency RoomsCompletedNCT02858687Not applicable1 country
- Evaluation of the Functional Impact of AdenotonsilectomyCompletedNCT055322281 country
- Children Recovering From Tonsil SurgeryStatus unknownNCT03292068Not applicable1 country
- Antimicrobial Stewardship Program (ASP) in Patients With a Sore ThroatCompletedNCT03408704Not applicable1 country
- Laryngeal Mask Airway in Pediatric AdenotonsillectomyCompletedNCT01695980Not applicable1 country
- Intelligent Customer-driven Solution for Children and Their Parents Undergoing Day SurgeryCompletedNCT04277299Not applicable1 country
- Effect of Tonsillectomy on Longterm Renal Outcome of IgA NephropathySuspendedNCT02471599Not applicable1 country
- Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing TonsillectomyCompletedNCT00654511Phase 41 country
- Perioperative Tonsillectomy Protocol DevelopmentStatus unknownNCT03323047Phase 41 country
- Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue DiseasesCompletedNCT046533761 country
- The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid OrgansStatus unknownNCT046465251 country
- Study of Imupret Application in the Technology of Delayed Prescription of Antibiotics in Patients With Acute TonsillitisCompletedNCT04537819Not applicable1 country
- Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and NauseaCompletedNCT02571075Not applicable1 country
- The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationTerminatedNCT02162433Phase 41 country
- KITS Study -Ketorolac In Tonsillectomy Surgery: a Double Blinded, Randomized Clinical TrialTerminatedNCT01498796Phase 21 country