Cancer Pain clinical trials
The registry lists 310 studies for Cancer Pain across more than 10 countries. 73 are recruiting or about to start. 183 of them are mainly about Cancer Pain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
Get an email when these change. Save the Cancer Pain studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Fujian Cancer Hospital (8) · M.D. Anderson Cancer Center (6) · Janssen Korea, Ltd., Korea (6) · Assiut University (4) · Memorial Sloan Kettering Cancer Center (4) · Taiwan Mundipharma Pharmaceuticals Ltd. (4) · Medstar Health Research Institute (4) · InSightec (4)
What is being tested here
Drugs under test in Cancer Pain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Fentanyl | 1 | 4 | 10 |
| Oxycodone | 1 | 2 | 10 |
| Morphine | 1 | 2 | 6 |
| Resiniferatoxin | 1 | 1 | 5 |
| Hydromorphone | 1 | 1 | 3 |
| Lidocaine | 1 | 1 | 2 |
| Ethanol | 1 | 0 | 2 |
| Ketamine | 1 | 0 | 2 |
| Dipyrone | 1 | 1 | 1 |
| Ibuprofen | 1 | 1 | 1 |
Drug classes tested here Opioids 4 open · Local anesthetics 1 open · Opioid antagonists 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management · Phase 3 · West China Hospital
- Dec 2026Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain · Dogwood Therapeutics Inc.
- Dec 20263D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain · 3D Medicines
- Dec 2026Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain · National Institute of Neurological Disorders and Stroke (NINDS)
- Dec 2026Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN) · Medstar Health Research Institute
- Dec 2026Evaluation of the Effects of Traditional and E-Learning Methods in Cancer Pain Care Education on Learning Outcomes and Institutional Costs · Bilecik Seyh Edebali Universitesi
- Dec 2026Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer Pain · Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- Jan 2027Prevention of Opioid-induced Constipation in Patients With Advanced Cancer · Amsterdam UMC, location VUmc
- Jan 2027Effectiveness of Phenotype-based Pain Management Guidelines for Head and Neck Cancer Related Pain: a Pilot Study · Shaukat Khanum Memorial Cancer Hospital & Research Centre
- Feb 2027Lidocaine Infusions for Pain in Patients With Malignant Bowel Obstruction · Fundación Santa Fe de Bogota
Who these studies take
Of the 43 Cancer Pain studies recruiting now, 31 (72%) set no upper age limit and 4 (9%) stop at 75 or younger. 4 (9%) take children under 18. 2 (5%) are for women only and 1 (2%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (9%) | 4 (9%) |
| 18 | 40 (93%) | 39 (91%) |
| 30 | 41 (95%) | 40 (93%) |
| 40 | 41 (95%) | 40 (93%) |
| 50 | 41 (95%) | 40 (93%) |
| 65 | 41 (95%) | 40 (93%) |
| 75 | 40 (93%) | 39 (91%) |
| 85 | 34 (79%) | 33 (77%) |
Across all 310 studies, recruiting or not: 15% stop at 75 or younger and 5% at 65; 5% take children; 4% are for women only and <1% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cancer Pain studies take
Of 15 phase 3 interventional studies under Cancer Pain, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 34 mo28–51 · 15 studies | — | — |
| Interventional, no phase | 18 mo10–40 · 75 studies | — | 17 mo10–40 · 72 studies |
| Observational | 24 mo16–40 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered3
- Effectiveness of Phenotype-based Pain Management Guidelines for Head and Neck Cancer Related Pain: a Pilot StudyNov 5, 2026NCT07919444
- Home-Based Foot Reflexology for Pain in Patients With Advanced CancerNov 4, 2026NCT07916402
- Dexmedetomidine for Refractory Pain in Palliative Cancer PatientsOct 21, 2026NCT07885475
Studies
Recruiting first, then most recently updated. Showing 50 of 310. Browse all 310 → or search them.
- Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesRecruitingNCT04907643Not applicable1 country
- Effectiveness of Phenotype-based Pain Management Guidelines for Head and Neck Cancer Related Pain: a Pilot StudyRecruitingNCT07919444Phase 21 country
- Cancer Pain Management Using a Web-based InterventionRecruitingNCT06085313Not applicable1 country
- Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone PainNot yet recruitingNCT02522611Phase 1/21 country
- Dexmedetomidine for Refractory Pain in Palliative Cancer PatientsRecruitingNCT078854751 country
- Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)RecruitingNCT07072468Phase 21 country
- Cancer Pain 101: A Digital, Asynchronous Intervention of Pain Management in Advanced CancerNot yet recruitingNCT07852468Not applicable1 country
- Real-world Study of the Effectiveness and Tolerability of Outpatient Titration of OxyContin for the Moderate and Severe Pain in Cancer PatientsNot yet recruitingNCT078697971 country
- Prevention of Opioid-induced Constipation in Patients With Advanced CancerRecruitingNCT05216328Phase 41 country
- Lidocaine Infusions for Pain in Patients With Malignant Bowel ObstructionNot yet recruitingNCT07856251
- Quad Shot Versus Split Course Radiotherapy in Incurable Head and Neck CancerNot yet recruitingNCT07823309Not applicable
- Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer SurvivorsRecruitingNCT06728579Phase 21 country
- Healing Gardens: Leveraging Serious Games to Deliver Accessible Pain-CBT and Pharmacologic Support for Patients With Advanced Cancer Managing PainNot yet recruitingNCT07825051Not applicable1 country
- Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer PainRecruitingNCT07396558Not applicable1 country
- Outcomes of Fluoroscopy-Guided Transdiscal Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain.Not yet recruitingNCT07825870Not applicable1 country
- ET-SPACE Whole-Body Infrared Hyperthermia in Patients With Advanced Solid TumorsRecruitingNCT077932141 country
- Single Fraction and Multifraction Arc-Based Radiotherapy for Painful Bone MetastasesNot yet recruitingNCT07772206Not applicable1 country
- Efficacy of Non-opioid Drugs in Addition to Opioid Therapy for Cancer Pain ManagementNot yet recruitingNCT07682558Phase 31 country
- Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer PainRecruitingNCT07489625Early Phase 11 country
- Evaluation of the Effects of Traditional and E-Learning Methods in Cancer Pain Care Education on Learning Outcomes and Institutional CostsNot yet recruitingNCT07461974Not applicable
- Intrathecal Therapy Versus Standard Care for Severe Cancer PainRecruitingNCT07691840Not applicable1 country
- RAD ONC FREEDOM Oncology PainRecruitingNCT07605546Not applicable1 country
- The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.RecruitingNCT07408193Early Phase 11 country
- Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer PainRecruitingNCT07657390Phase 1/21 country
- Effects of Opioid Drugs on Sleep and Emotion in Patients With Moderate to Severe Cancer PainRecruitingNCT076166481 country
- Efficacy of Spinal Cord Stimulation in Chemotherapy-Induced Peripheral NeuropathyNot yet recruitingNCT07579611Not applicable1 country
- Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic CancerRecruitingNCT06160323Not applicable1 country
- A Randomized Controlled Trial of a Web-based Platform for Cancer Pain ManagementRecruitingNCT06663956Phase 31 country
- Virtual Reality Therapy for Cancer-Treatment Associated SymptomsRecruitingNCT06248216Not applicable1 country
- Enhancing Pain Management Among Patients Diagnosed With Stage III and Stage IV of Breast Cancer: The Power of Immersive and Non-Immersive Virtual Reality-Driven Interactive Guided ImageryNot yet recruitingNCT07497451Not applicable1 country
- 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer PainNot yet recruitingNCT05265052Phase 2
- Developing a Multimodal Cancer Pain Database to Support AI-Based Automatic Pain AssessmentRecruitingNCT072626321 country
- A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their PainRecruitingNCT07447856Phase 11 country
- Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer PainRecruitingNCT07445386Not applicable1 country
- Assessing Hydromorphone Sustained-Release Tablets in Elderly Cancer Pain Patients With Renal InsufficiencyNot yet recruitingNCT074216741 country
- Stereotactic MRI-guided Focused Ultrasound MesencephalotomyRecruitingNCT07405645Not applicable1 country
- A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With PainRecruitingNCT073261371 country
- MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain PatientsNot yet recruitingNCT074000551 country
- Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor ExcisionRecruitingNCT07382297Not applicable1 country
- Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy PainNot yet recruitingNCT07337330Not applicable1 country
- Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.RecruitingNCT07327138Not applicable1 country
- Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)RecruitingNCT07318519Not applicable1 country
- Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer PainRecruitingNCT07308951Not applicable1 country
- Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) StudyRecruitingNCT07228377Not applicable1 country
- UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized PatientsNot yet recruitingNCT07265492
- Spinal Palliation in Irradiation for Neoplastic Analgesia and Life QualityRecruitingNCT06884332Not applicable1 country
- Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE)RecruitingNCT047262281 country
- Implementation of Personalized Medicine for Optimal Drug Therapy in CancerRecruitingNCT058302791 country
- e-Natureza Blue Care: Nature-based Virtual Reality and Pain PerceptionNot yet recruitingNCT07053228Not applicable1 country
- Effect of Transcutaneous Electrical Nerve Stimulation or Acupressure on Pain in Patients With Head and Neck CancerEnrolling by invitationNCT07051265Not applicable1 country