Mayo Clinic clinical trials
Listed in the registry as: University, hospital or other organization.
The registry lists 3,263 studies whose lead sponsor is Mayo Clinic. 670 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 23, 2026.
Keep track of what changes. Save the Mayo Clinic studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
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Focus areas
Conditions Mayo Clinic leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Breast Neoplasms134Multiple Myeloma83Neoplasms75Prostatic Neoplasms68Heart Failure64Obesity60Diabetes Mellitus54Lung Neoplasms53Carcinoma44Melanoma43Lymphoma42Barrett Esophagus39Leukemia, Lymphocytic, Chronic, B-Cell36Pancreatic Neoplasms36Cardiovascular Diseases34Carcinoma, Non-Small-Cell Lung32Atrial Fibrillation31Depression31Hypertension30Heart Diseases29Diabetes Mellitus, Type 228Brain Neoplasms27COVID-1926Irritable Bowel Syndrome26
Show all 116 areas
Leukemia26Plasmacytoma26Eosinophilic Esophagitis25Esophagitis25Coronary Artery Disease24Alzheimer Disease23Gastroesophageal Reflux23Glioblastoma23Insulin Resistance23Infections22Ovarian Neoplasms22Depressive Disorder21Glioma21Tobacco Use Disorder21Cognitive Dysfunction20Crohn Disease20Epilepsy20Osteoarthritis20Pain, Postoperative20Endometrial Neoplasms19Myocardial Infarction19Cholangiocarcinoma18Kidney Diseases18Lymphoma, Non-Hodgkin18Wounds and Injuries18Cardiomyopathies17Communicable Diseases17Dementia17Liver Diseases17Neoplasm Metastasis17Parkinson Disease17Sleep Apnea, Obstructive17Amyloidosis16Carcinoma, Hepatocellular16Colorectal Neoplasms16Head and Neck Neoplasms16Lymphoma, Large B-Cell, Diffuse16Adenocarcinoma15Cholangitis, Sclerosing15Lymphoma, B-Cell15Osteoarthritis, Knee15Sleep Apnea Syndromes15Carcinoma, Renal Cell14Constipation14Depressive Disorder, Major14Diabetes Mellitus, Type 114Lung Diseases14Lymphoma, B-Cell, Marginal Zone14Lymphoma, Follicular14Migraine Disorders14Renal Insufficiency14Sarcoma14Bipolar Disorder13Constriction, Pathologic13Diarrhea13Fallopian Tube Neoplasms13Fractures, Bone13Hot Flashes13Lymphoma, Mantle-Cell13Myocardial Ischemia13Polycystic Kidney, Autosomal Dominant13Stroke13Waldenstrom Macroglobulinemia13Acute Kidney Injury12Breast Carcinoma In Situ12Central Nervous System Neoplasms12Colitis, Ulcerative12Esophageal Neoplasms12Fatigue12Lymphoma, T-Cell12Pancreatitis12Peripheral Nervous System Diseases12Pulmonary Disease, Chronic Obstructive12Uterine Cervical Neoplasms12Carcinoma, Ovarian Epithelial11Headache11Hemorrhage11Oropharyngeal Neoplasms11Overweight11Renal Insufficiency, Chronic11Skin Neoplasms11Urinary Bladder Neoplasms11Amyotrophic Lateral Sclerosis10Atherosclerosis10Hypertension, Pulmonary10Joint Diseases10Lung Diseases, Obstructive10Mycosis Fungoides10Myeloproliferative Disorders10Osteoporosis10Pancreatitis, Chronic10Spinal Cord Injuries10
Studies
Recruiting first, then most recently updated. Showing 50 of 3,263. Browse all 3,263 →
- Ravulizumab in Pregnancies Complicated by Severe Hypertensive DisordersRecruitingNCT06333652Phase 2
- A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular DysplasiaRecruitingNCT07526766Not applicable
- A Community Based Intervention to Improve Cervical Cancer Screening Among Women in the Hispanic and East African Immigrant CommunityRecruitingNCT07890402Not applicable
- Weight Loss Through Mayo Clinic DietRecruitingNCT06862375Not applicable
- Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot StudyRecruitingNCT07886203
- Wisconsin Ginseng for Decreasing Cancer Related FatigueRecruitingNCT06395441Phase 3
- Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell TherapyRecruitingNCT06834373Phase 2
- Pharmacokinetics Of Emulsified Avacopan Applied By NG TubeRecruitingNCT07556484Phase 1
- Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:RecruitingNCT06322238Phase 2
- Accelerated Resolution Therapy for Early Maladaptive GriefRecruitingNCT05624879Not applicable
- The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 DiabetesRecruitingNCT06976619Phase 2
- Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison StudyRecruitingNCT06972056Phase 4
- A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic DizzinessEnrolling by invitationNCT07420803Not applicable
- EMG ss AMG In Robotic/Laparoscopic SurgeryEnrolling by invitationNCT07525323Not applicable
- A Study Of T1/Tref Intubating ConditionsEnrolling by invitationNCT07483164Not applicable
- Varenicline for Smoking Cessation in PancreatitisNot yet recruitingNCT07874841Phase 4
- Conducting Wound, Ostomy, and Continence (WOC) Nurse Telephone Follow-up for Post-discharge Ostomy Patients to Reduce Hospital ReadmissionRecruitingNCT07879872Not applicable
- Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing SurgeryRecruitingNCT06450873Phase 2
- INTERogating Cancer for Etiology, Prevention and Therapy NavigationRecruitingNCT06008392
- Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase InhibitorsRecruitingNCT06028022Phase 2
- Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's DiseaseRecruitingNCT06065436Not applicable
- Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal, Gynecological, Breast, or Lung CancerRecruitingNCT06855524Phase 2
- Intravenous Ketamine for Treatment-Resistant DepressionRecruitingNCT06668571Phase 2
- Descriptions and Practices of Family Engagement in Emergency Care SettingRecruitingNCT07739576
- EEG-Guided Transcranial Magnetic Stimulation for Adults With DepressionNot yet recruitingNCT07862205Not applicable
- Evaluating the Efficacy of a "Quiet Knee Protocol" in Primary Total Knee Arthroplasty (TKA): A Prospective Randomized StudyRecruitingNCT07879014Not applicable
- Electronic Approach to the Human Massage TherapistRecruitingNCT07040397Not applicable
- Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype GlioblastomaRecruitingNCT07708961Phase 2
- Bladder Bank (a Prospective Banking Study)RecruitingNCT06109857
- Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate CancerRecruitingNCT06325046Not applicable
- Impact of RFA on Esophageal Distensibility and Mucosal ImpedanceRecruitingNCT07126535
- A Screening Program to Improve the Early Detection of Sporadic Pancreatic Cancer in Individuals With a High-Risk of Developing Pancreatic CancerRecruitingNCT07324096Not applicable
- Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation TherapyRecruitingNCT04082520Phase 2
- Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer PatientsRecruitingNCT05045066Early Phase 1
- Effect of Sacubitril-Valsartan on Cardiac Structure and FunctionRecruitingNCT06693674Phase 3
- Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)RecruitingNCT06676579Phase 2
- Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording ApparatusesRecruitingNCT07868614
- In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE TrialRecruitingNCT06704191Phase 1/2
- Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant MenEnrolling by invitationNCT06472817
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)RecruitingNCT04363684
- Insulin and Insulin Pulses During FastingRecruitingNCT06424015Not applicable
- Surgical Resection of Latent Brain Tumors Prior to RecurrenceRecruitingNCT04810871Not applicable
- Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for Improving Disease-Related Symptoms in Patients With Unresectable Solid TumorsRecruitingNCT07856394Not applicable
- Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR TrialRecruitingNCT07188532Not applicable
- The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityRecruitingNCT07218445Phase 4
- Biorepository of Biomarkers for Optimization of Microvascular Treatment of LymphedemaEnrolling by invitationNCT04123457
- Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast AbnormalitiesRecruitingNCT06058650Not applicable
- Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver CancerRecruitingNCT03942328Phase 1/2
- The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older AdultsRecruitingNCT06940037Not applicable
- Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor AgonistsRecruitingNCT07006142Not applicable