Drug
Furosemide clinical trials
Also written Lasix, Frusemide and Lasix ONYU.
How each study uses Furosemide is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Furosemide studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- 1 Jul 1966 · LASIX · NDA 016273 (FDA, Drugs@FDA)
- European Union
- 29 May 2026 · Bopediat · EMEA/H/C/006617 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
157 studies that test it; most in 2015 (16); 1 more planned to start later
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 5 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 4 |
| 2009 | 6 |
| 2010 | 6 |
| 2011 | 5 |
| 2012 | 7 |
| 2013 | 6 |
| 2014 | 5 |
| 2015 | 16 |
| 2016 | 12 |
| 2017 | 10 |
| 2018 | 5 |
| 2019 | 7 |
| 2020 | 7 |
| 2021 | 9 |
| 2022 | 2 |
| 2023 | 11 |
| 2024 | 10 |
| 2025 | 4 |
| 2026 | 12 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 27 · Other 133
Boehringer Ingelheim (7) · Assistance Publique - Hôpitaux de Paris (4) · University of North Carolina, Chapel Hill (3) · University of Palermo (3) · AstraZeneca (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Children's Hospital Medical Center, Cincinnati (2) · University of Texas Southwestern Medical Center (2)
Often tested with
Tested in the same studies.
Rosuvastatin (8) · Digoxin (7) · Hydrochlorothiazide (6) · Metformin (6) · Spironolactone (5) · Torsemide (3) · Metolazone (3) · Isosorbide Dinitrate (3)
Related medicines
As reviewed, each with the page that says it.
- One of Diuretics source
- One of Loop diuretics source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 9
Studies that test Furosemide.
- Nov 2026Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart FailurePhase 4 · University of Florida
- Dec 2026Kidney Sodium Content in Cardiorenal PatientsNot applicable · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Mar 2027Role of Postpartum Furosemide in Recovery of Patients With Severe PreeclampsiaNot applicable · Lady Reading Hospital, Pakistan
- Mar 2027Furosemide vs Placebo in Severe Preeclampsia PostpartumPhase 2 · Universidad Nacional Autonoma de Honduras
- Apr 2027Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.Phase 4 · Morten H. Bestle
- May 2027DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart FailurePhase 4 · Copenhagen University Hospital, Rigshospitalet
- Jun 2027Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart FailurePhase 4 · Lakeland Regional Health Systems, Inc.
- Jun 2027Contrast-Induced Acute Kidney Injury Prevention in Acute Heart FailureNot applicable · Jin Joo Park
- Sep 2027Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart FailurePhase 4 · University of Aarhus
Studies
Open first, then newest update. How each study uses Furosemide is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 160
- Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With LaserRecruitingPhase 3University Hospital, ToursNCT05916963Written as Furosemide 40 mg
- Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart FailureNot yet recruitingPhase 3University of Texas Southwestern Medical CenterNCT07018297Written as Early Discharge with Lasix® ONYU (furosemide injection, for subcutaneous use) using SQIN-Infusor
- Furosemide vs Placebo in Severe Preeclampsia PostpartumNot yet recruitingPhase 2Universidad Nacional Autonoma de HondurasNCT07648251Written as Furosemide
- Optimizing Preeclampsia Postpartum With Point-of-care UltrasoundRecruitingPhase 4University of California, IrvineNCT07167862Written as Oral furosemide
- Effect of a Furosemide Stress Test-Guided Strategy on Liberation From Continuous Renal Replacement Therapy in Critically Ill Patients With Acute Kidney InjuryRecruitingPhase 4Chiang Mai UniversityNCT06229990Written as Furosemide Injection
- DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart FailureRecruitingPhase 4Copenhagen University Hospital, RigshospitaletNCT05276219Written as Furosemide Injection
- Role of Postpartum Furosemide in Recovery of Patients With Severe PreeclampsiaRecruitingNot applicableLady Reading Hospital, PakistanNCT07861685Written as Furosemide and Potassium
- The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal TransplantationRecruitingNot applicableLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNCT07726134Written as Furosemide
- Contrast-Induced Acute Kidney Injury Prevention in Acute Heart FailureRecruitingNot applicableJin Joo ParkNCT07550790Written as Furosemide
- Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart FailureRecruitingPhase 4University of AarhusNCT07577596Written as Intravenous furosemide continuous infusion
- Bumetanide vs. Furosemide in CirrhosisRecruitingPhase 3Stacy JohnsonNCT06941415Written as Furosemide
- "Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function"RecruitingNot applicableJose J Zaragoza, MD MScNCT07417969Written as Furosemide plus albumin
- Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart FailureRecruitingPhase 4University of FloridaNCT06979726Written as Lasix ONYU
- Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.RecruitingPhase 4Morten H. BestleNCT04180397Written as Furosemide
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Furosemide
- Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart FailureRecruitingPhase 4Lakeland Regional Health Systems, Inc.NCT07263035Written as Furosemide intravenous solution
- Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI StudyRecruitingPhase 4University of DelawareNCT06094816Written as Furosemide (Diuretic)
- Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical ProceduresRecruitingNot applicableCairo UniversityNCT07348510Written as Furosemide
- Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and AscentRecruitingNot applicableNational Aeronautics and Space Administration (NASA)NCT06467825Written as Furosemide 20 MG
- Role of Intralesional Combined Injection of Furosemide and Digoxin in Cutaneous Warts At Tertiary Care Hospital in Karachi.Enrolling by invitationEarly Phase 1Jinnah Postgraduate Medical CentreNCT06821594Written as Furosemide
See all 160 studies that test Furosemide →
Given beside what is tested · 33 — Furosemide is usual care or a partner of the new treatment
- DESAL-HEART: Hypertonic Saline Added to a Pre-declared Furosemide Dose in Acute Heart FailureNot yet recruitingPhase 4University of AlbertaNCT07927127Written as Furosemide (Diuretic)
- ACetazolamide in Patients With Heart Failure, to Decrease Weight and relIEVE Symptoms.Not yet recruitingPhase 3University Hospital, MontpellierNCT07737964Written as Furosemide
- Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in CardiorenalNot yet recruitingPhase 3University of MonastirNCT07596329Written as Furosemide intravenous solution
- SURE-HF: Urinary Sodium-Guided Diuretic Therapy in Heart FailureNot yet recruitingNot applicableNurgul AblakimovaNCT07631780Written as Furosemide
- 18F-DOPA II - PET Imaging OptimizationRecruitingPhase 3University of AlbertaNCT04706910Written as Furosemide Injection
- Acetazolamide or Metolazone in Acute Heart FailureNot yet recruitingNot applicableClinica Alemana de SantiagoNCT06273397Written as Furosemide Injection
- Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill AdultsRecruitingPhase 2/3University of MalayaNCT05933642Written as Frusemide
- Natriuresis With Acetazolamide or SGLT2 Inhibitors Added to Intravenous Loop Diuretics in Decompensated Heart FailureActive, not recruitingPhase 4Universidade do PortoNCT07926958Written as Furosemide
- Magnesium Supplementation for the Prevention of Cisplatin-Induced NephrotoxicityCompletedNot applicableGrigore T. Popa University of Medicine and PharmacyNCT07874373Written as Furosemide
- Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic MelanomaActive, not recruitingPhase 1M.D. Anderson Cancer CenterNCT05470283Written as Furosemide
- A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005)CompletedPhase 1Merck Sharp & Dohme LLCNCT07431866Written as Furosemide
- Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)CompletedPhase 1ShionogiNCT04481789Written as Furosemide
- Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic PatientsTerminatedPhase 4Rush University Medical CenterNCT04216784Written as Furosemide Injection
- Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。CompletedPhase 1Jiangsu HengRui Medicine Co., Ltd.NCT07073157Written as HRS-8427 injection plus furosemide
- Diuretic Strategies in Acute Heart Failure Patients At High Risk for Diuretic ResistanceTerminatedPhase 4Stadtspital ZürichNCT05986773Written as Furosemide
- Voxelotor CYP and Transporter Cocktail Interaction StudyCompletedPhase 1PfizerNCT05981365Written as Furosemide
- Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart FailureCompletedPhase 3Wroclaw Medical UniversityNCT05962255Written as Furosemide intravenous infusion
- Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) PatientsCompletedPhase 1/2Actinium PharmaceuticalsNCT02575963Written as Furosemide (Phase 1 only)
- Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail ApproachCompletedEarly Phase 1Washington State UniversityNCT03772262Written as Furosemide
- Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart FailureCompletedPhase 2/3scPharmaceuticals, Inc.NCT02329834Written as Furosemide Injection, USP
Showing 20 of 33.
As the comparator · 18 — what is tested is compared with Furosemide
- Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)RecruitingNot applicableReprieve Cardiovascular, IncNCT06898515Written as furosemide infusion
- Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart FailureCompletedPhase 1/2SQ Innovation, Inc.NCT04384653Written as Furosemide Injection, USP
- Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg FurosemideTerminatedPhase 1Sarfez Pharmaceuticals, Inc.NCT03509545Written as CHF Patients: Furosemide 40 mg
- A Study of Ultra High Dose Diuretics to Treat Heart FailureCompletedPhase 2Mayo ClinicNCT06036914Written as Furosemide
- New Horizons for the Treatment of Cardiomyopathy in ChildrenTerminatedNot applicableDamascus UniversityNCT04893629Written as Digoxin+furosemide+captopril
- Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart FailureWithdrawnPhase 2/3Jan Kochanowski UniversityNCT05652322Written as Furosemide Injection
- Amiloride in Nephrotic SyndromeTerminatedPhase 3University Hospital TuebingenNCT05079789Written as Furosemide
- Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.CompletedPhase 3Puerta de Hierro University HospitalNCT04533997Written as Intravenous furosemide
- Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct EdemaTerminatedPhase 3Eurofarma Laboratorios S.A.NCT01210365Written as Lasix ®
- A Trial to Study BAY1753011 in Patients With Congestive Heart FailureCompletedPhase 2BayerNCT03901729Written as Furosemide
- Effectiveness of a Diuretic Algorithm in Clinical Stability in Heart Failure PatientsCompletedNot applicableHospital de Clinicas de Porto AlegreNCT02068937Written as Furosemide
- Aquaresis Utility for Hyponatremic Acute Heart Failure StudyCompletedPhase 4University of Southern CaliforniaNCT02183792Written as Furosemide
- A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)TerminatedPhase 1Merck Sharp & Dohme LLCNCT01558674Written as Furosemide
- The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart FailureStatus unknownPhase 4Medical University of WarsawNCT01942109Written as Furosemide
- Intra-Renal Therapy of Diuretic Unresponsive Acute Kidney InjuryWithdrawnPhase 4Southeast Renal Research InstituteNCT01073189Written as Furosemide
- Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid OverloadWithdrawnNot applicableM.D. Anderson Cancer CenterNCT01508260Written as Furosemide
- Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart FailureCompletedPhase 3Aspirus Heart and Vascular Institute-Research and EducationNCT01028170Written as furosemide
- Effect of a New Formulation of Torasemide (Prolonged Release)on Myocardial Fibrosis in Patients With Heart Failure.CompletedPhase 4Ferrer Internacional S.A.NCT00409942Written as Furosemide
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Optimizing Preeclampsia Postpartum With Point-of-care UltrasoundNov 2, 2026NCT07167862
Codes
What other systems call Furosemide · ClinicalTrials.gg INT007532
- MeSH (NLM) D005665FurosemideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7LXU5N7ZO5FUROSEMIDEConfirmed FDA, NLM, Wikidata
- RxNorm 4603Confirmed FDA, Wikidata
- Wikidata Q388801furosemideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C515FurosemideOne source FDA
- DrugBank DB00695One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D005665 | Furosemide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7LXU5N7ZO5 | FUROSEMIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4603 | — | Confirmed FDA, Wikidata |
| Wikidata | Q388801 | furosemide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C515 | Furosemide | One source FDA |
| DrugBank | DB00695 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.