Kidney Failure, Chronic clinical trials
The registry lists 2,108 studies for Kidney Failure, Chronic across more than 10 countries. 273 are recruiting or about to start. 1,646 of them are mainly about Kidney Failure, Chronic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 5,320 studies for Kidney Failure, Chronic. How that becomes 2,107 here
This page counts the studies the registry files under Kidney Failure, Chronic, and those it files under no condition that list Kidney Failure, Chronicthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 5,320Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −181List Kidney Failure, Chronic as a condition, but the registry did not file them under itMost often written as “End Stage Renal Failure on Dialysis” (30), “Renal Failure Chronic” (18), and “End Stage Renal Disease on Dialysis” (18). The registry filed them under other conditions only, most often Renal Insufficiency, Chronic (103) and Renal Insufficiency (18).
- −3,037Match it another way216 name it in the title, 4 in a keyword, and 2,817 by a synonym or other text the search reads.
- 2,102Counted here and found by its search98 of them list Kidney Failure, Chronic in their own words; the registry filed them under no condition.
- +5
Counted here, but its search does not find them
- Primary Patency in Pediatric Patients With Hemodialysis AccessNCT06034717
- Evaluation of a Marine OXYgen Carrier for Organ PreservationNCT04181710
- Evaluation of a Marine OXYgen Carrier: HEMO2Life® for hypOthermic Kidney Graft Preservation, Before Transplantation (OXYOP)NCT02652520
- Wearable Ambulatory Vs. Office BP in HemodialysisNCT07762859
- Nutritional Assessment of Children With ESRD on DialysisNCT04177368
- 2,107The count on this page
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Status
Who runs them
Vantive Health LLC (32) · National Taiwan University Hospital (25) · Amgen (20) · University of Washington (18) · Assiut University (17) · Satellite Healthcare (17) · Emory University (16) · National Institute of Allergy and Infectious Diseases (NIAID) (16)
What is being tested here
Drugs under test in Kidney Failure, Chronic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Empagliflozin | 3 | 1 | 7 |
| Tegoprubart | 3 | 1 | 4 |
| Roxadustat | 2 | 5 | 13 |
| Apixaban | 2 | 2 | 7 |
| Probiotic | 2 | 1 | 3 |
| Tacrolimus | 1 | 2 | 13 |
| Spironolactone | 1 | 2 | 12 |
| Sodium Bicarbonate | 1 | 0 | 5 |
| Imlifidase | 1 | 1 | 5 |
| Dapagliflozin | 1 | 1 | 5 |
Drug classes tested here SGLT2 inhibitors 6 open · Diuretics 2 open · Factor Xa inhibitors 2 open · Calcineurin inhibitors 1 open · Mineralocorticoid receptor antagonists (MRAs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease · Phase 3 · Amicus Therapeutics
- Dec 2026CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes · Phase 3 · VA Office of Research and Development
- Dec 2026Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. · Phase 3 · Iperboreal Pharma Srl
- Mar 2027Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile · Phase 3 · Roberto Gedaly
- May 2027meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis · Phase 3 · University Health Network, Toronto
- May 2027Belatacept as a Replacement for CNIs 3 to 12 Months Post-transplantation in Patients With Early Graft Dysfunction · Phase 3 · Nantes University Hospital
- Jun 2027To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis · Phase 3 · Humacyte, Inc.
- Jun 2027CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease · Phase 3 · Vanderbilt University Medical Center
- Oct 2027Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients · Phase 3 · Ain Shams University
- Oct 2027A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease · Phase 3 · Astellas Pharma Global Development, Inc.
Who these studies take
Of the 170 Kidney Failure, Chronic studies recruiting now, 109 (64%) set no upper age limit and 32 (19%) stop at 75 or younger. 18 (11%) take children under 18. 0 (0%) are for women only and 1 (1%) for men only; 22 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 11 (6%) | 12 (7%) |
| 18 | 149 (88%) | 149 (88%) |
| 30 | 161 (95%) | 161 (95%) |
| 40 | 163 (96%) | 163 (96%) |
| 50 | 164 (96%) | 164 (96%) |
| 65 | 161 (95%) | 161 (95%) |
| 75 | 148 (87%) | 148 (87%) |
| 85 | 123 (72%) | 123 (72%) |
Across all 2,108 studies, recruiting or not: 20% stop at 75 or younger and 9% at 65; 9% take children; <1% are for women only and 1% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Kidney Failure, Chronic studies take
Of 67 phase 1 interventional studies under Kidney Failure, Chronic, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 12 mo5–27 · 67 studies | 7 mo5–16 · 46 studies | — |
| Phase 1/2 | 35 mo25–54 · 29 studies | — | — |
| Phase 2 | 32 mo17–55 · 67 studies | 24 mo17–56 · 26 studies | 35 mo25–52 · 41 studies |
| Phase 3 | 32 mo21–48 · 66 studies | 30 mo20–40 · 42 studies | — |
| Phase 4 | 31 mo16–54 · 63 studies | — | 37 mo17–80 · 52 studies |
| Interventional, no phase | 23 mo8–46 · 425 studies | 18 mo8–40 · 78 studies | 23 mo8–47 · 347 studies |
| Observational | 29 mo11–62 · 150 studies | — | 30 mo11–62 · 131 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting4
- Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot TrialNov 6, 2026NCT07910773
- Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal DiseaseNov 2, 2026NCT07696962
- Dry Weight Reduction Intervention Via Extra UltrafiltrationOct 30, 2026NCT07637110
- Laser Acupuncture for Fatigue in Hemodialysis PatientsOct 26, 2026NCT07538310
Results posted3
- Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal TransplantOct 30, 2026NCT03380962
- Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKDOct 30, 2026NCT05614115
- Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW StudyOct 29, 2026NCT05309109
Newly registered12
- Nurse-Led Interventions Addressing Physical Exercise and Psychological Needs on Enhancing Outcomes in Patients With Chronic Renal FailureNov 10, 2026NCT07927660
- Hypothermic Kidney Machine Perfusion With OmnisolNov 6, 2026NCT07920926
- Comparative Feasibility and Effectiveness of Medically Tailored Meals Approaches for Pediatric End-Stage Kidney DiseaseNov 3, 2026NCT07911969
- Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot TrialNov 2, 2026NCT07910773
- Cycling During Dialysis: A Feasibility and Safety StudyOct 30, 2026NCT07905885
Show 7 moreShow fewer
- Bisoprolol Versus Cognitive Behavioral Therapy for Stress in Patients on Peritoneal DialysisOct 27, 2026NCT07899281
- Microbiota Changes Related to Outcomes in Kidney TransplantationOct 26, 2026NCT07893691
- Low-Dose Spironolactone in Hemodialysis Patients With Resistant HypertensionOct 22, 2026NCT07888504
- Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney DiseaseOct 21, 2026NCT07887607
- Ramipril vs. Amlodipine in Pediatric Hemodialysis PatientsOct 19, 2026NCT07879560
- Unmasking Diabetes in Dialysis With Continuous Glucose MonitoringOct 19, 2026NCT07880795
- Study on the Safety and Efficacy of a Time-of-Day-Based Individualized Tacrolimus Dosing Regimen in Kidney Transplant RecipientsOct 16, 2026NCT07877103
Studies
Recruiting first, then most recently updated. Showing 50 of 2,108. Browse all 2,108 → or search them.
- Imlifidase Prior to Kidney Transplant in Highly Sensitised ChildrenRecruitingNCT05753930Phase 26 countries
- Nurse-Led Interventions Addressing Physical Exercise and Psychological Needs on Enhancing Outcomes in Patients With Chronic Renal FailureRecruitingNCT07927660Not applicable1 country
- Hypothermic Kidney Machine Perfusion With OmnisolNot yet recruitingNCT07920926Not applicable
- Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal DiseaseRecruitingNCT07696962Phase 11 country
- Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot TrialRecruitingNCT07910773Not applicable1 country
- Physical Impairments in Children With Chronic Renal FailureRecruitingNCT069815851 country
- Post Market Study for VasQ, an External Support Implant for Arteriovenous FistulaRecruitingNCT06516653Not applicable1 country
- A Study to Test the Safety of the Study Drug Fosmanogepix and How the Body Handles It in Adults With Severe Kidney Failure on DialysisRecruitingNCT07916181Phase 11 country
- Comparative Feasibility and Effectiveness of Medically Tailored Meals Approaches for Pediatric End-Stage Kidney DiseaseNot yet recruitingNCT07911969Not applicable
- Bupropion for Fatigue in End-stage Kidney Disease Patients on HemodialysisNot yet recruitingNCT06609343Phase 1/21 country
- Cycling During Dialysis: A Feasibility and Safety StudyNot yet recruitingNCT07905885Not applicable
- Dry Weight Reduction Intervention Via Extra UltrafiltrationRecruitingNCT07637110Not applicable1 country
- Effects of Horticultural Therapy on Acute Stress and Salivary Cortisol Levels in Hemodialysis PatientsNot yet recruitingNCT07845214Not applicable
- Empagliflozin in Heart Failure With Reduced Ejection Fraction and End Stage Renal DiseaseRecruitingNCT06249932Phase 41 country
- Maturation of Arteriovenous Fistula With Automated Sonography Assessments TrialRecruitingNCT06190717Not applicable1 country
- Unmasking Diabetes in Dialysis With Continuous Glucose MonitoringNot yet recruitingNCT078807951 country
- Laser Acupuncture for Fatigue in Hemodialysis PatientsRecruitingNCT07538310Not applicable1 country
- Microbiota Changes Related to Outcomes in Kidney TransplantationNot yet recruitingNCT078936911 country
- Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis PatientsRecruitingNCT06483074Phase 21 country
- Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)RecruitingNCT070599622 countries
- Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney DiseaseNot yet recruitingNCT07887607Not applicable1 country
- Ramipril vs. Amlodipine in Pediatric Hemodialysis PatientsNot yet recruitingNCT07879560Phase 3
- Bisacodyl Oral for Lowering Dysfunction (of Tenckhoff Catheter)RecruitingNCT07351357Phase 41 country
- Technology-enabled Social Network Intervention to Increase Live Donor Kidney TransplantationNot yet recruitingNCT07072767Not applicable1 country
- β2M Post-HD Rebound PredictionRecruitingNCT077136801 country
- Study on the Safety and Efficacy of a Time-of-Day-Based Individualized Tacrolimus Dosing Regimen in Kidney Transplant RecipientsNot yet recruitingNCT07877103Phase 41 country
- CSP #2026 - Beta Blocker Dialyzability on Cardiovascular OutcomesRecruitingNCT05931276Phase 31 country
- Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD )Not yet recruitingNCT07867444Not applicable
- Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional HemodialysisRecruitingNCT05642156Not applicable1 country
- Blood Volume Monitoring Via Critline in Volume Overload: Hospitalization and ReadmissionEnrolling by invitationNCT078668721 country
- Ultrasound Guidance Intercostobrachial Nerve Block in AVF SuperficializationNot yet recruitingNCT07852351Not applicable
- Study of 3 Monoclonal Antibodies (REGN9933, REGN7508, and REGN9533) in Adult Participants With End-Stage Kidney Disease on HemodialysisRecruitingNCT07759167Phase 11 country
- The Solaris DE Sirolimus-Eluting Covered Stent for the Treatment of AV Access Stenosis or OcclusionRecruitingNCT06096142Not applicable1 country
- A Study to Evaluate the Pharmacokinetics and Safety of INCB161734 in Participants With Impaired Renal Function and Participants on HemodialysisNot yet recruitingNCT07854249Phase 1
- Intravascular Ultrasound in Patients With End-stage Renal Disease on DialysisRecruitingNCT04399941Not applicable1 country
- A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal FunctionRecruitingNCT07763418Phase 11 country
- A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of RibupatideRecruitingNCT07793929Phase 11 country
- Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell CarcinomaRecruitingNCT05287945Phase 1/25 countries
- Drone Transport of Deceased-Donor Kidney Grafts Between Two French Hospitals Before Transplantation: a Pilot Safety StudyNot yet recruitingNCT07851571Not applicable
- Study of Tegoprubart Efficacy and Safety Compared With Tacrolimus in Kidney TransplantationNot yet recruitingNCT07835581Phase 3
- DIALysis With EXpanded Solute RemovalRecruitingNCT06660277Not applicable1 country
- Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)RecruitingNCT05485961Phase 2/335 countries
- DialysisBot: AI Chatbot for Hemodialysis Self-ManagementNot yet recruitingNCT07830810Not applicable1 country
- Twice vs Thrice Weekly Hemodialysis: Clinical Outcomes and Quality of LifeNot yet recruitingNCT07821788
- PATH-03 Paraguay Feasibility StudyNot yet recruitingNCT07034092Not applicable1 country
- Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective RegistryRecruitingNCT058805371 country
- Peritoneal Dialysis Registration System (PERSIST)RecruitingNCT029892981 country
- Hyperparathyroidism and Dialysis Adequacy in Hemodialysis PatientsNot yet recruitingNCT07820150
- Partners Calciphylaxis BiobankRecruitingNCT030328351 country
- AVF Awareness Among Advanced CKD PatientsNot yet recruitingNCT07817953