Hypertension, Pregnancy-Induced clinical trials
The registry lists 262 studies for Hypertension, Pregnancy-Induced across more than 10 countries. 71 are recruiting or about to start. 106 of them are mainly about Hypertension, Pregnancy-Induced (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its 3 narrower conditions too, such as Pre-Eclampsia: 1,052 studies, 281 open.
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Status
Who runs them
University of Oxford (8) · University of Pennsylvania (6) · Massachusetts General Hospital (5) · Northwestern University (4) · Columbia University (4) · Saint Thomas Hospital, Panama (4) · The University of Texas Health Science Center, Houston (3) · Ohio State University (3)
What is being tested here
Drugs under test in Hypertension, Pregnancy-Induced studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Labetalol | 4 | 4 | 11 |
| Nifedipine | 4 | 2 | 11 |
| Aspirin | 4 | 2 | 5 |
| Enalapril | 2 | 1 | 3 |
| Furosemide | 1 | 2 | 6 |
| Dipyridamole | 1 | 0 | 1 |
| Atorvastatin | 1 | 0 | 1 |
| Eplerenone | 1 | 0 | 1 |
| Chlorthalidone | 1 | 0 | 1 |
| Potassium Chloride | 1 | 0 | 1 |
Drug classes tested here Calcium channel blockers 4 open · NSAIDs 4 open · Diuretics 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Oct 2027Cardiovascular Protection After Preeclampsia With Enalapril · Phase 3 · Women and Infants Hospital of Rhode Island
- Nov 2026Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Quality · Jun Wei
- Dec 2026Telehealth and Remote Blood Pressure · Wake Forest University Health Sciences
- Dec 2026Inorganic Nitrate Supplementation in Chronic Hypertensive Pregnancies · University of Sao Paulo
- Dec 2026The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy. · University of Alabama at Birmingham
- Dec 2026Vascular Biomarkers Predictive of the Progression From Hypertensive Disorders in Pregnancy to Preeclampsia in Pregnant Women · Assistance Publique - Hôpitaux de Paris
- Dec 2026Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy · Northwestern University
- Dec 2026Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and Hypertension · University of the Punjab
- Dec 2026Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA Study · Muğla Sıtkı Koçman University
- Dec 2026Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant Women · Dr. Sunita Pun
Who these studies take
Of the 54 Hypertension, Pregnancy-Induced studies recruiting now, 24 (44%) set no upper age limit and 29 (54%) stop at 75 or younger. 7 (13%) take children under 18. 51 (94%) are for women only and 0 (0%) for men only; 16 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 47 (87%) | 2 (4%) |
| 30 | 53 (98%) | 3 (6%) |
| 40 | 51 (94%) | 3 (6%) |
| 50 | 37 (69%) | 2 (4%) |
| 65 | 28 (52%) | 2 (4%) |
| 75 | 25 (46%) | 2 (4%) |
| 85 | 25 (46%) | 2 (4%) |
Across all 262 studies, recruiting or not: 54% stop at 75 or younger and 53% at 65; 17% take children; 96% are for women only and 0% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypertension, Pregnancy-Induced studies take
Of 91 interventional studies with no phase under Hypertension, Pregnancy-Induced, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo10–34 · 91 studies | — | 24 mo9–34 · 90 studies |
| Observational | 40 mo12–119 · 49 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 262. Browse all 262 → or search them.
- Rhode Island - Statewide Postpartum Hypertension Remote SurveillanceRecruitingNCT06842875Not applicable1 country
- Placental Biology in Health and DiseaseRecruitingNCT074703201 country
- Community Support and Mobile Apps to Help Black Women Control High Blood Pressure After PregnancyNot yet recruitingNCT07606027Not applicable
- Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood PressureRecruitingNCT07778966Not applicable1 country
- Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIALRecruitingNCT06468202Phase 41 country
- AtorvaStatin Postpartum and Reduction of Cardiovascular risKRecruitingNCT06632379Phase 41 country
- Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of PregnancyRecruitingNCT07238400Phase 21 country
- MumCare: Mum's Cardiovascular Health for LifeEnrolling by invitationNCT05835596Not applicable1 country
- MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)RecruitingNCT07842341Not applicable1 country
- Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA StudyRecruitingNCT078741911 country
- Role of Postpartum Furosemide in Recovery of Patients With Severe PreeclampsiaRecruitingNCT07861685Not applicable1 country
- Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) DisparitiesNot yet recruitingNCT06915428Not applicable1 country
- Roy Adaptation Model-Based Prenatal Education in Hypertensive Pregnant WomenNot yet recruitingNCT07820306Not applicable1 country
- Treatment With Aspirin After Preeclampsia: TAP TrialRecruitingNCT06281665Phase 41 country
- Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST TrialNot yet recruitingNCT07746271Phase 31 country
- REmote Physical ACtivity Intervention for High Blood Pressure PostpartumNot yet recruitingNCT07127731Not applicable
- PROTECT-Africa: Biomarker Validation for Preeclampsia TriageRecruitingNCT078104391 country
- Exploring the Effect of Discharge Education, Blood Pressure Cuffs, and Postpartum Bracelets to Improve Health Among Newly Diagnosed Gestational Hypertension and Preeclampsia Patients During the Postpartum Period.Not yet recruitingNCT07807098Not applicable
- Vagal Stimulation Therapy and PreeclampsiaRecruitingNCT06953115Not applicable1 country
- Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot ProjectRecruitingNCT05989581Phase 11 country
- Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.Enrolling by invitationNCT07751432Not applicable1 country
- Cardiovascular Protection After Preeclampsia With EnalaprilRecruitingNCT07222852Phase 31 country
- Dipyridamole for Early-Onset Preeclampsia: A Pilot Study of Feasibility, Pharmacokinetics, and Biological EffectsNot yet recruitingNCT07738562Phase 1/21 country
- Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Pregnant Women With Hypertensive Disorders of PregnancyRecruitingNCT077286561 country
- Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following PreeclampsiaRecruitingNCT06220721Not applicable1 country
- Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and HypertensionRecruitingNCT07551011Not applicable1 country
- Delivering HOPE (Helping Women Optimize Prenatal Equity)RecruitingNCT06814509Not applicable1 country
- Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of PregnancyRecruitingNCT05826925Not applicable1 country
- Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in PregnancyNot yet recruitingNCT07656532Not applicable1 country
- Moms@Home: A Storytelling-based Mobile Health Intervention to Improve Blood Pressure Management in PregnancyRecruitingNCT06835959Not applicable1 country
- PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and EfficacyRecruitingNCT06915792Phase 41 country
- Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant PatientsRecruitingNCT06466161Not applicable1 country
- Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum HypertensionRecruitingNCT07209254Not applicable1 country
- Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive PregnanciesRecruitingNCT05434195Not applicable1 country
- Hypertension Explored in Long-term Postpartum Follow-up in Later LifeRecruitingNCT061870121 country
- Telehealth and Remote Blood PressureRecruitingNCT07356518Not applicable1 country
- Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee WomenRecruitingNCT066475111 country
- Inorganic Nitrate Supplementation in Chronic Hypertensive PregnanciesRecruitingNCT06105775Not applicable1 country
- PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)RecruitingNCT072634901 country
- Spironolactone to Improve Pregnancy-Associated Hypertension TrajectoriesRecruitingNCT07041281Phase 21 country
- Basic and Clinical Research of Pregnancy-Induced HypertensionRecruitingNCT074643791 country
- A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)RecruitingNCT06785116Phase 41 country
- Safest Choice of Antihypertensive Regimen for Postpartum HypertensionRecruitingNCT05551104Phase 31 country
- Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant WomenNot yet recruitingNCT07373756Phase 4
- LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia PreventionRecruitingNCT07361679Phase 41 country
- Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of PreeclampsiaRecruitingNCT073492771 country
- The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.RecruitingNCT05676476Not applicable1 country
- Peking University Birth Cohort in Weifang (PKUBC-WF)RecruitingNCT062343321 country
- Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring GuidelinesEnrolling by invitationNCT065765441 country
- Postpartum Evaluation of Nifedipine and Enalapril for HypertensionRecruitingNCT07023003Phase 41 country