Kidney Calculi clinical trials
The registry lists 509 studies for Kidney Calculi across more than 10 countries. 146 are recruiting or about to start. 423 of them are mainly about Kidney Calculi (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
ClinicalTrials.gov finds 826 studies for Kidney Calculi. How that becomes 509 here
This page counts the studies the registry files under Kidney Calculi, and those it files under no condition that list Kidney Calculithemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 826Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −5List Kidney Calculi as a condition, but the registry did not file them under itMost often written as “Uric Acid Kidney Stone Disease” (1), “Rare Kidney Stone Diseases” (1), and “Calcium Phosphate Kidney Stones” (1). The registry filed them under other conditions only, most often Nephrolithiasis (3) and Hyperoxaluria, Primary (1).
- −312Match it another way45 name it in the title, 1 in a keyword, and 266 by a synonym or other text the search reads.
- 509The count on this page3 of them list Kidney Calculi in their own words; the registry filed them under no condition.
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Status
Who runs them
The First Affiliated Hospital of Guangzhou Medical University (22) · University of Alabama at Birmingham (17) · Ain Shams University (14) · Mansoura University (12) · University of British Columbia (12) · Northwestern University (9) · Indiana Kidney Stone Institute (9) · University of Chicago (9)
What is being tested here
Drugs under test in Kidney Calculi studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Citric Acid | 3 | 1 | 10 |
| Potassium Citrate | 3 | 1 | 9 |
| Empagliflozin | 2 | 1 | 3 |
| Chlorthalidone | 2 | 0 | 3 |
| Sodium Bicarbonate | 2 | 0 | 3 |
| Tamsulosin | 1 | 2 | 8 |
| Ketorolac | 1 | 0 | 6 |
| Hydrochlorothiazide | 1 | 1 | 3 |
| Ketorolac Tromethamine | 1 | 0 | 3 |
| Carbon-13 | 1 | 0 | 2 |
Drug classes tested here Diuretics 3 open · NSAIDs 2 open · Local anesthetics 2 open · Thiazide diuretics 2 open · Opioids 6
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Surgical Outcomes and Costs in Using the Shenzhen HugeMed 6.3 French Flexible Ureteroscope · University of Kansas Medical Center
- Nov 2026Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones · Al-Azhar University
- Nov 2026Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes · University of Kansas Medical Center
- Nov 2026Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery · Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
- Nov 2026New Laser and Suction Sheath for Kidney Stone Treatment · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Nov 2026Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Dec 2026Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention · Rabin Medical Center
- Dec 2026Novel Antimicrobial Solution to Prevent Infections · Ohio State University
- Dec 2026Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet · University of Texas Southwestern Medical Center
- Dec 2026Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis · The Cleveland Clinic
Who these studies take
Of the 88 Kidney Calculi studies recruiting now, 48 (55%) set no upper age limit and 23 (26%) stop at 75 or younger. 6 (7%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 11 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (5%) | 4 (5%) |
| 18 | 84 (95%) | 84 (95%) |
| 30 | 87 (99%) | 87 (99%) |
| 40 | 87 (99%) | 87 (99%) |
| 50 | 87 (99%) | 87 (99%) |
| 65 | 85 (97%) | 85 (97%) |
| 75 | 71 (81%) | 71 (81%) |
| 85 | 54 (61%) | 54 (61%) |
Across all 509 studies, recruiting or not: 29% stop at 75 or younger and 13% at 65; 11% take children; <1% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Kidney Calculi studies take
Of 199 interventional studies with no phase under Kidney Calculi, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 26 mo12–51 · 199 studies | — | 31 mo13–54 · 183 studies |
| Observational | 42 mo14–52 · 39 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence StudyNov 2, 2026NCT07155005
- FANS vs CVAC for Medium to Large StonesOct 16, 2026NCT07514351
Newly registered9
- Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous NephrolithotomyNov 2, 2026NCT07908992
- Comparison of Smart Pressure-Controlled Flexible Ureteroscopy and Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy for 2-3 cm Renal StonesNov 2, 2026NCT07909577
- TZ-RIRS vs. C-RIRS for Kidney StonesOct 30, 2026NCT07906964
- Phosphate & Kidney StonesOct 29, 2026NCT07903961
- Ureteral Access Strategies in Retrograde Intrarenal SurgeryOct 27, 2026NCT07898020
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- Supine vs. Prone Mini-PCNL in ChildrenOct 22, 2026NCT07887945
- Novel Antimicrobial Solution to Prevent InfectionsOct 19, 2026NCT07881822
- The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic PerformanceOct 13, 2026NCT07870928
- Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH).Oct 13, 2026NCT07871669
Studies
Recruiting first, then most recently updated. Showing 50 of 509. Browse all 509 → or search them.
- Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With LaserRecruitingNCT05916963Phase 31 country
- Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence StudyRecruitingNCT071550051 country
- Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous NephrolithotomyNot yet recruitingNCT07908992Not applicable1 country
- Comparison of Smart Pressure-Controlled Flexible Ureteroscopy and Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy for 2-3 cm Renal StonesNot yet recruitingNCT07909577Not applicable
- Phosphate & Kidney StonesNot yet recruitingNCT07903961Early Phase 11 country
- Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration TechnologyRecruitingNCT07101809Not applicable1 country
- Ureteral Access Strategies in Retrograde Intrarenal SurgeryNot yet recruitingNCT07898020Not applicable1 country
- Fecal Microbiota Transplantation in Kidney Stone PatientsRecruitingNCT05516472Early Phase 11 country
- Comparison of Suction and Conventional Ureteral Access Sheaths in Kidney Stone SurgeryRecruitingNCT078662091 country
- Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of NephrolithiasisRecruitingNCT05993546Not applicable1 country
- Novel Antimicrobial Solution to Prevent InfectionsNot yet recruitingNCT07881822
- DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal StonesNot yet recruitingNCT07516535Not applicable1 country
- Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE PreventionRecruitingNCT06653738Phase 34 countries
- Supine vs. Prone Mini-PCNL in ChildrenRecruitingNCT07887945Not applicable1 country
- FANS vs CVAC for Medium to Large StonesRecruitingNCT07514351Not applicable1 country
- Observational Approach Versus Surgical Intervention for StonesRecruitingNCT07718802Not applicable1 country
- The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic PerformanceNot yet recruitingNCT07870928
- Gut Oxalate Absorption in Calcium Oxalate Stone DiseaseRecruitingNCT06331546Not applicable1 country
- O. Formigenes Colonization in Calcium Oxalate Kidney Stone DiseaseRecruitingNCT06330246Not applicable1 country
- Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH).Not yet recruitingNCT07871669Phase 2
- Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)RecruitingNCT07587021Phase 21 country
- Direct In-Scope Suction Versus Standard Flexible UreterorenoscopyRecruitingNCT07864194Not applicable1 country
- Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT)RecruitingNCT07859436Not applicable1 country
- Nephrostomy Tract Infiltration for Pain Control After PCNLRecruitingNCT07721571Not applicable1 country
- Modified SOLTIVE StudyNot yet recruitingNCT078380771 country
- FANS-Optimization of Irrigation and Suction Parameters in RIRSNot yet recruitingNCT07840482Not applicable
- Assessment of Urinary Microplastic Concentration in Patients With Urolithiasis: A Prospective Case-Control StudyNot yet recruitingNCT07841834
- Effect of Emergency Urinary Drainage on Subsequent PCNL Outcomes in Obstructive UrosepsisRecruitingNCT07826325Not applicable1 country
- Pilot Study of Patient Navigation for Kidney Stone Patients After ED VisitsNot yet recruitingNCT07322172Not applicable1 country
- 6.3Fr Versus 7.5Fr Mini-Flexible Ureteroscopy for Renal Stones (MINI-FURS)Not yet recruitingNCT07798336Not applicable1 country
- SGLT2i in Kidney StonesRecruitingNCT07055282Early Phase 11 country
- Heterozygous Individuals for AGXT and Kidney StonesEnrolling by invitationNCT04430426Not applicable1 country
- Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone DiseaseRecruitingNCT06989320Not applicable1 country
- Ureteral Stenting After Retrograde Intrarenal Surgery for Renal StonesRecruitingNCT05738304Not applicable1 country
- Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible UreteroscopesRecruitingNCT07773090Not applicable1 country
- Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)RecruitingNCT07776626Phase 11 country
- CaOx Stone PreventionRecruitingNCT07225764Phase 41 country
- Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone SurgeryNot yet recruitingNCT077636001 country
- Pain Control During ESWL Using Non-Opioid AnalgesicsNot yet recruitingNCT07512297Phase 41 country
- Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNLNot yet recruitingNCT07749807Not applicable1 country
- DISON I - Directly Integrated Suction and Optics System for the Treatment of NephrolithiasisNot yet recruitingNCT07712861Not applicable5 countries
- 2D:4D Digit Ratio and Urinary Stone DiseaseNot yet recruitingNCT077369241 country
- Intraoperative Assessment of of Burst Wave Lithotripsy (BWL)RecruitingNCT03873259Not applicable1 country
- Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis SurgeryRecruitingNCT07620873Not applicable1 country
- Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal SurgeryNot yet recruitingNCT07705646Not applicable1 country
- Modified Mini-PCNL Versus Standard PCNL for Complex Kidney StonesRecruitingNCT07697677Not applicable1 country
- Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)RecruitingNCT06721975Not applicable1 country
- Comparison of Vacuum-Assisted and Conventional Ureteral Access Sheath in Retrograde Intrarenal SurgeryRecruitingNCT06684756Not applicable1 country
- Kidney Stone InflammationRecruitingNCT064362351 country
- Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cmNot yet recruitingNCT07689565Not applicable1 country