Bronchopulmonary Dysplasia clinical trials
The registry lists 362 studies for Bronchopulmonary Dysplasia across more than 10 countries. 85 are recruiting or about to start. 225 of them are mainly about Bronchopulmonary Dysplasia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
NICHD Neonatal Research Network (14) · Children's Hospital of Philadelphia (10) · University of Alabama at Birmingham (9) · Centre Hospitalier Intercommunal Creteil (6) · Medipost Co Ltd. (6) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (5) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Rigshospitalet, Denmark (5)
What is being tested here
Drugs under test in Bronchopulmonary Dysplasia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Corticosteroids 3 open · Stimulants 3 open · Diuretics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Mar 2027Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention · Phase 3 · Rigshospitalet, Denmark
- Oct 2027Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress · Phase 3 · Ministry of Health, Saudi Arabia
- Nov 2026Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
- Nov 2026Genesis Electrical Impedance Tomography (EIT): A Preliminary Study · University of Colorado, Denver
- Nov 2026Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial). · Murdoch Childrens Research Institute
- Nov 2026Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants · Aristotle University Of Thessaloniki
- Dec 2026Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data · Konya City Hospital
- Dec 2026Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit · Shirley Ryan AbilityLab
- Jan 2027Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants · EXO Biologics S.A.
- Feb 2027Lung Ultrasound Score for Early Prediction of Bronchopulmonary Dysplasia in Preterm Newborns · Azienda USL Reggio Emilia - IRCCS
Who these studies take
Of the 58 Bronchopulmonary Dysplasia studies recruiting now, 7 (12%) set no upper age limit and 50 (86%) stop at 75 or younger. 56 (97%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 11 (19%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 9 (16%) | 9 (16%) |
| 18 | 11 (19%) | 10 (17%) |
| 30 | 9 (16%) | 8 (14%) |
| 40 | 9 (16%) | 8 (14%) |
| 50 | 8 (14%) | 7 (12%) |
| 65 | 8 (14%) | 7 (12%) |
| 75 | 8 (14%) | 7 (12%) |
| 85 | 8 (14%) | 7 (12%) |
Across all 362 studies, recruiting or not: 85% stop at 75 or younger and 85% at 65; 98% take children; 1% are for women only and 1% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bronchopulmonary Dysplasia studies take
Of 19 phase 2 interventional studies under Bronchopulmonary Dysplasia, half reached primary completion within 61 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 61 mo42–69 · 19 studies | — | — |
| Interventional, no phase | 37 mo19–63 · 73 studies | — | 29 mo18–56 · 71 studies |
| Observational | 56 mo19–84 · 48 studies | — | 56 mo19–84 · 46 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- The Correlation Between Red Cell Transfusion and Complications of PrematurityOct 22, 2026NCT07123948
Newly registered3
- Late Low-Dose Dexamethasone in Preterm Neonates Using DART ProtocolOct 29, 2026NCT07904104
- Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover TrialOct 26, 2026NCT07895654
- Impact of Higher Zinc Supplementation on Neonatal Weight VelocityOct 26, 2026NCT07896070
Studies
Recruiting first, then most recently updated. Showing 50 of 362. Browse all 362 → or search them.
- Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm InfantsNot yet recruitingNCT07502781Not applicable1 country
- Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)RecruitingNCT05849077Not applicable1 country
- Controlled Remote Monitoring and Optimization of Oxygen Therapy in Preterm InfantsRecruitingNCT07161908Not applicable1 country
- Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover TrialNot yet recruitingNCT07895654Not applicable1 country
- Impact of Higher Zinc Supplementation on Neonatal Weight VelocityRecruitingNCT07896070Phase 41 country
- Ventilator Pressure and Optimization of Compliance and HemodynamicsRecruitingNCT06512935Not applicable1 country
- Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary DysplasiaRecruitingNCT06954142Not applicable1 country
- The Correlation Between Red Cell Transfusion and Complications of PrematurityRecruitingNCT071239481 country
- Use of Mesenchymal Stem Cells in Pre-term Patients With Bronchopulmonary Dysplasia.RecruitingNCT06270199Phase 21 country
- Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)RecruitingNCT06897839Phase 2/38 countries
- Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm InfantsRecruitingNCT06373289Not applicable1 country
- Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature InfantsNot yet recruitingNCT07848646
- High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm InfantsRecruitingNCT07307612Phase 1/21 country
- Parent Perceptions of OptiPAP JuniorNot yet recruitingNCT07837700Not applicable1 country
- Predictors of Prolonged Mechanical Ventilation in Preterm InfantsNot yet recruitingNCT07821632
- Baby ABS (Abdominal Binder Study)RecruitingNCT07049900Not applicable1 country
- Inhaled Ciclesonide Study in Preterm InfantsRecruitingNCT06589245Phase 11 country
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT042784042 countries
- Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm InfantsNot yet recruitingNCT077713871 country
- Chloride Imbalance in Preterm InfantsRecruitingNCT069408561 country
- Lipid Infusions to Optimize Nutrition TrialRecruitingNCT06915441Phase 21 country
- Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary DysplasiaRecruitingNCT064759761 country
- Lung Ultrasound Score for Early Prediction of Bronchopulmonary Dysplasia in Preterm NewbornsRecruitingNCT076331841 country
- Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and BelowRecruitingNCT07561125Phase 21 country
- Transpyloric Versus Gastric Feeding in Bronchopulmonary DysplasiaRecruitingNCT06534359Not applicable1 country
- PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary DysplasiaRecruitingNCT07101640Phase 1/21 country
- Continued Pressure for Alveolar Protection (CPAP Trial)RecruitingNCT07417111Not applicable1 country
- Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical DataNot yet recruitingNCT075251671 country
- Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care UnitRecruitingNCT06000761Not applicable1 country
- Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm InfantsRecruitingNCT05777512Not applicable1 country
- The Diaphragmatic Initiated Ventilatory Assist (DIVA) TrialRecruitingNCT05446272Not applicable2 countries
- National Surveillance and Prevention of Neonatal VAPNot yet recruitingNCT071097911 country
- Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature InfantsRecruitingNCT07652684Phase 41 country
- OCTA Evaluation of Retinal Vascularization in Preterm Infants With or Without Bronchopulmonary DysplasiaNot yet recruitingNCT07586683Not applicable1 country
- Pharmacokinetics and Placental Transfer of CaffeineRecruitingNCT07570121Phase 11 country
- Implementation of a Consensus-Based Discharge Protocol for Preterm Infants With Lung DiseaseRecruitingNCT052853451 country
- IVIG Trial for the Treatment of Bronchopulmonary DysplasiaRecruitingNCT06925360Phase 21 country
- Point of Care Lung Ultrasound in Preterm Infants With Respiratory DistressEnrolling by invitationNCT059250751 country
- Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NECRecruitingNCT05636397Not applicable1 country
- Impact of the Early Life Virome Development on Bronchopulmonary Dysplasia in Preterm NeonatesNot yet recruitingNCT07487259
- Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?Not yet recruitingNCT07447739Phase 21 country
- Pressure-Sensing Mattresses and Mechanical Ventilation Weaning in NeonatalRecruitingNCT065791571 country
- Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and MortalityRecruitingNCT072736431 country
- Pressure Targeting During High Flow Therapy in Premature InfantsNot yet recruitingNCT07418502Phase 21 country
- PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm InfantsNot yet recruitingNCT07411261Not applicable1 country
- Combined Oscillation-Volume guarantEe StudyNot yet recruitingNCT07377955Not applicable
- Metformin for Premature Infants With Bronchopulmonary DysplasiaRecruitingNCT07120971Early Phase 11 country
- Forced Oscillometry in Infants With Bronchopulmonary DysplasiaRecruitingNCT042700451 country
- MRI in BPD SubjectsRecruitingNCT036576931 country
- Anakinra Pilot 2 - A Study to Optimise Dose and Route of Administration of Anakinra in Preterm InfantsRecruitingNCT07254000Phase 22 countries