Coronary Artery Disease clinical trials
The registry lists 4,861 studies for Coronary Artery Disease across more than 10 countries. 892 are recruiting or about to start. 3,801 of them are mainly about Coronary Artery Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 12,218 studies for Coronary Artery Disease. How that becomes 4,856 here
This page counts the studies the registry files under Coronary Artery Disease, and those it files under no condition that list Coronary Artery Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 12,218Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −101List Coronary Artery Disease as a condition, but the registry did not file them under itMost often written as “Multivessel Coronary Artery Disease” (16), “Microvascular Coronary Artery Disease” (13), and “Multi Vessel Coronary Artery Disease” (12). The registry filed them under other conditions only, most often ST Elevation Myocardial Infarction (16) and Angina Pectoris (15).
- −7,261Match it another way345 name it in the title, 22 in a keyword, and 6,894 by a synonym or other text the search reads.
- 4,856The count on this page113 of them list Coronary Artery Disease in their own words; the registry filed them under no condition.
Get an email when these change. Save the Coronary Artery Disease studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
Abbott Medical Devices (79) · Yonsei University (64) · Seung-Jung Park (59) · China National Center for Cardiovascular Diseases (57) · National Heart, Lung, and Blood Institute (NHLBI) (48) · Boston Scientific Corporation (46) · Seoul National University Hospital (44) · Cordis Corporation (41)
What is being tested here
Drugs under test in Coronary Artery Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 7 | 6 | 52 |
| Colchicine | 6 | 5 | 23 |
| Ticagrelor | 5 | 18 | 74 |
| Prasugrel | 4 | 8 | 40 |
| PCSK9 Inhibitor | 4 | 0 | 4 |
| Clopidogrel | 3 | 8 | 71 |
| Rivaroxaban | 3 | 3 | 14 |
| Empagliflozin | 3 | 0 | 8 |
| Dapagliflozin | 3 | 0 | 7 |
| Semaglutide | 3 | 2 | 5 |
Drug classes tested here P2Y12 inhibitors 10 open · NSAIDs 8 open · SGLT2 inhibitors 6 open · GLP-1 receptor agonists 4 open · Statins 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Canagliflozin Targeting Vascular Inflammation · Phase 3 · Ottawa Heart Institute Research Corporation
- Jan 2027Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy · Phase 3 · iVascular S.L.U.
- Mar 2027Colchicine Use for Primary Prevention of Coronary Artery Disease · Phase 3 · Qingdao Central Hospital
- Jun 2027Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR) · Phase 3 · Sinotau Pharmaceutical Group
- Jul 2027Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled Trial · Phase 3 · Montreal Heart Institute
- Oct 2027A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery. · Phase 3 · EBI Anti Sepsis BV
- Nov 2027A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque · Phase 3 · NewAmsterdam Pharma
- Nov 2027Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention · Phase 3 · AZ Sint-Jan AV
- Nov 2026The Bioresorbable Implants for Scaffolding Obstructions in Randomized Bifurcations (BIFSORB) Study · Aarhus University Hospital Skejby
- Nov 2026PRE-DETERMINE Cohort Study · Brigham and Women's Hospital
Who these studies take
Of the 588 Coronary Artery Disease studies recruiting now, 403 (69%) set no upper age limit and 68 (12%) stop at 75 or younger. 38 (6%) take children under 18. 7 (1%) are for women only and 7 (1%) for men only; 47 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 31 (5%) | 31 (5%) |
| 18 | 446 (76%) | 443 (75%) |
| 30 | 526 (89%) | 524 (89%) |
| 40 | 549 (93%) | 549 (93%) |
| 50 | 565 (96%) | 566 (96%) |
| 65 | 569 (97%) | 570 (97%) |
| 75 | 545 (93%) | 544 (93%) |
| 85 | 465 (79%) | 463 (79%) |
Across all 4,861 studies, recruiting or not: 14% stop at 75 or younger and 4% at 65; 7% take children; 1% are for women only and 2% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Coronary Artery Disease studies take
Of 193 phase 4 interventional studies under Coronary Artery Disease, half reached primary completion within 35 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 7 mo4–27 · 34 studies | — | — |
| Phase 2 | 28 mo16–39 · 55 studies | 15 mo9–29 · 26 studies | — |
| Phase 3 | 47 mo20–58 · 61 studies | 49 mo24–55 · 29 studies | — |
| Phase 4 | 35 mo19–58 · 193 studies | — | 36 mo21–59 · 180 studies |
| Interventional, no phase | 30 mo15–50 · 930 studies | 24 mo14–40 · 177 studies | 33 mo15–53 · 753 studies |
| Observational | 41 mo21–87 · 760 studies | 27 mo15–40 · 125 studies | 48 mo23–122 · 635 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting11
- A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular DiseaseNov 10, 2026NCT07839936
- Clinical Information System Impact on Hospitalized Patients With Chronic DiseaseNov 9, 2026NCT07609381
- Randomized Prospective Trial on the Cost-Effectiveness of Photon-Counting CT Versus Energy-Integrating Detector CT in Suspected Chronic Coronary SyndromeNov 6, 2026NCT07831304
- Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass SurgeryNov 6, 2026NCT07898215
- AI-Assisted Interpretation of Cardiac CT in the Emergency DepartmentNov 5, 2026NCT07235657
Show 6 moreShow fewer
- Safety and Efficacy of Very Short DAPT in Older Patients Undergoing PCINov 3, 2026NCT07164859
- A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.Nov 2, 2026NCT07357675
- Lifewise Preventive Video Education in Primary CareOct 29, 2026NCT06730737
- Cardiovascular Acoustics for Early Disease DetectionOct 28, 2026NCT07496775
- Treatment of Primary Coronary Artery Vascular Lesions With Biolimus Coated Coronary Balloon Dilation CatheterOct 27, 2026NCT06385067
- Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery DiseaseOct 20, 2026NCT07875088
Results posted1
- Benidipine in Hypertensive and/or Chronic Coronary Syndrome PatientsNov 4, 2026NCT06808321
Stopped2
- Is Our Microbiome a Predictor of Cardiac RiskSuspendedOct 20, 2026NCT02013284
- 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACSWithdrawnOct 19, 2026NCT06409117
Newly registered28
- Nurse-Led Self-Management Support After Coronary Artery Bypass SurgeryNov 12, 2026NCT07930819
- Prognostic Value of Oxygen-15 Water PET in Coronary Artery DiseaseNov 12, 2026NCT07932314
- Prospective Cohort Study of Patients Undergoing Coronary Angiography in Vorarlberg, AustriaNov 12, 2026NCT07932327
- Hybrid Parasternal Intercostal Plane Block Versus No Block for Postoperative Analgesia After Cardiac Surgery Via Median SternotomyNov 12, 2026NCT07934290
- TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic StenosisNov 9, 2026NCT07926022
Show 23 moreShow fewer
- Preoperative Gastric Ultrasound and Anaesthetic Management in Patients Undergoing Coronary Artery Bypass GraftingNov 6, 2026NCT07922395
- Partial Cardiac Denervation for Preventing Atrial Fibrillation After CABGNov 5, 2026NCT07918781
- Sirolimus-Coated Versus Paclitaxel-Coated Balloon for Recurrent Coronary In-Stent Restenosis After Prior Paclitaxel-Coated Balloon Treatment (SPRIT)Nov 5, 2026NCT07920055
- Hs-CRP-Guided Colchicine Treatment Targets in Very-High-Risk Patients With Coronary Artery Disease After PCI (TARGET-CHD)Nov 5, 2026NCT07920133
- Assessment of Transnational Performance of the Universal Cardiac Surgical Risk Score Across International SitesNov 5, 2026NCT07920575
- Coronary Myocardial Bridge and Coronary Plaques on MDCTNov 4, 2026NCT07916272
- Computational μFR-Guided Versus Angiographic Guidance in Drug-Coated Balloon AngioplastyNov 4, 2026NCT07917234
- ADVA ACE Coronary Stent System in Coronary Artery Disease Patients (ADVANCE)Nov 3, 2026NCT07912541
- Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass SurgeryNov 3, 2026NCT07912801
- Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass SurgeryOct 27, 2026NCT07898215
- Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCIOct 27, 2026NCT07898709
- TRADENT Scoring Balloon Versus Non-scoring Balloon for Lesion Preparation in DCB-Based Coronary InterventionOct 27, 2026NCT07899021
- EDIT-401 in Adults Who Require Additional Lowering of Low-Density Lipoprotein Cholesterol (LDL-C)Oct 26, 2026NCT07894887
- The CORE Platform TrialOct 23, 2026NCT07892976
- MCG Algorithm Optimization Study in Patients With Coronary Artery StenosisOct 22, 2026NCT07888465
- AI-Based CT Analysis of Coronary Plaque EvolutionOct 21, 2026NCT07886996
- Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABGOct 20, 2026NCT07883499
- Vascular Inflammation in Atherosclerosis - Whole Body Molecular PET/CT Imaging Using Folate Receptor βOct 16, 2026NCT07877324
- Serratus Anterior Plane Block for Recovery After Minimally Invasive CABGOct 16, 2026NCT07877532
- Erectile and Ejaculatory Function Following Coronary RevascularizationOct 16, 2026NCT07878260
- 1-Month Versus 6-Month Dual Antiplatelet Therapy After Successful Drug-Coated Balloon-Only Percutaneous Coronary InterventionOct 16, 2026NCT07879430
- Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery DiseaseOct 15, 2026NCT07875088
- Modified Jailed Balloon Technique vs Jailed Wire Technique in Coronary Bifurcation InterventionOct 14, 2026NCT07873879
Studies
Recruiting first, then most recently updated. Showing 50 of 4,861. Browse all 4,861 → or search them.
- The NAVIGATE-PCI Registry: A New Approach to VIew CT-derived Guidance Ahead of Stenting To Plan Efficient PCIRecruitingNCT074794331 country
- Comparison of the Use of an Outpatient/Mobile MRI Procedure With an Inpatient MRI Procedure in Adult Patients With Known or Suspected Coronary Artery Disease (CAD)Not yet recruitingNCT062461881 country
- Nurse-Led Self-Management Support After Coronary Artery Bypass SurgeryNot yet recruitingNCT07930819Not applicable1 country
- Hybrid Parasternal Intercostal Plane Block Versus No Block for Postoperative Analgesia After Cardiac Surgery Via Median SternotomyNot yet recruitingNCT07934290Not applicable1 country
- ULTIMATE Study (Carotid Ultrasound Vs CT Coronary Calcium Scoring to Reclassify Symptomatic Patients With Chronic Coronary Syndrome)RecruitingNCT07696533Not applicable1 country
- Prospective Cohort Study of Patients Undergoing Coronary Angiography in Vorarlberg, AustriaRecruitingNCT079323271 country
- Prognostic Value of Oxygen-15 Water PET in Coronary Artery DiseaseRecruitingNCT07932314Phase 31 country
- The Influence of Modifying Highly Calcified Coronary Lesions on Coronary MicrocirculationEnrolling by invitationNCT06507449Not applicable1 country
- Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled TrialRecruitingNCT07524335Phase 31 country
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable4 countries
- Health Coaching for Patients With Cardiovascular DiseaseNot yet recruitingNCT06904144Not applicable1 country
- Blood Collection for Research Related to Certain Diseases Involving Blood VesselsEnrolling by invitationNCT000479961 country
- Vascular Senescence and Atherosclerotic Plaque VulnerabilityRecruitingNCT063136451 country
- PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosisRecruitingNCT07232069Phase 31 country
- Study to Determine the Clinical Significance of Intravascular OCT-NIRAFEnrolling by invitationNCT06374498Not applicable1 country
- A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)RecruitingNCT07286578Not applicable4 countries
- A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular DiseaseRecruitingNCT07839936Phase 21 country
- TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic StenosisRecruitingNCT079260221 country
- Clinical Information System Impact on Hospitalized Patients With Chronic DiseaseRecruitingNCT076093811 country
- Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronary Artery Disease: Validation by Quantitative Cardiac MRI PerfusionRecruitingNCT07068399Not applicable1 country
- PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEmRecruitingNCT06445608Not applicable1 country
- Preoperative Gastric Ultrasound and Anaesthetic Management in Patients Undergoing Coronary Artery Bypass GraftingNot yet recruitingNCT079223951 country
- Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass SurgeryNot yet recruitingNCT07912801Phase 41 country
- Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass SurgeryRecruitingNCT078982151 country
- Randomized Prospective Trial on the Cost-Effectiveness of Photon-Counting CT Versus Energy-Integrating Detector CT in Suspected Chronic Coronary SyndromeRecruitingNCT07831304Not applicable1 country
- The Bridging Antiplatelet Therapy With Cangrelor 2 StudyRecruitingNCT07225842Phase 41 country
- Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery LesionsRecruitingNCT06779630Not applicable6 countries
- Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney TransplantationRecruitingNCT062344101 country
- Hs-CRP-Guided Colchicine Treatment Targets in Very-High-Risk Patients With Coronary Artery Disease After PCI (TARGET-CHD)Not yet recruitingNCT07920133Not applicable1 country
- Partial Cardiac Denervation for Preventing Atrial Fibrillation After CABGNot yet recruitingNCT07918781Not applicable1 country
- CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain SyndromesRecruitingNCT04709900Not applicable1 country
- Sirolimus-Coated Versus Paclitaxel-Coated Balloon for Recurrent Coronary In-Stent Restenosis After Prior Paclitaxel-Coated Balloon Treatment (SPRIT)Not yet recruitingNCT07920055Not applicable1 country
- Assessment of Transnational Performance of the Universal Cardiac Surgical Risk Score Across International SitesNot yet recruitingNCT07920575
- AI-Assisted Interpretation of Cardiac CT in the Emergency DepartmentRecruitingNCT07235657Not applicable1 country
- A Phase 2b Clinical Trial of YN001 in Adults With Coronary AtherosclerosisRecruitingNCT07521007Phase 24 countries
- The DANE-HEART Trial - Computed Tomography Coronary Angiography for Primary PreventionEnrolling by invitationNCT05677386Not applicable1 country
- Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH TrialRecruitingNCT07120776Not applicable1 country
- Computational μFR-Guided Versus Angiographic Guidance in Drug-Coated Balloon AngioplastyRecruitingNCT07917234Not applicable1 country
- Coronary Myocardial Bridge and Coronary Plaques on MDCTRecruitingNCT079162721 country
- A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac DiseaseRecruitingNCT044646551 country
- Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG SurgeryRecruitingNCT07163858Not applicable1 country
- Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT)RecruitingNCT048273161 country
- ADVA ACE Coronary Stent System in Coronary Artery Disease Patients (ADVANCE)Not yet recruitingNCT07912541Not applicable
- PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility StudyNot yet recruitingNCT053773201 country
- Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary InterventionsRecruitingNCT05732701Not applicable3 countries
- Safety and Efficacy of Very Short DAPT in Older Patients Undergoing PCIRecruitingNCT07164859Phase 31 country
- A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.RecruitingNCT07357675Phase 34 countries
- Aggressive Lipid Lowering Therapy in ICI-Treated MelanomaRecruitingNCT07704918Not applicable1 country
- Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)RecruitingNCT07296744Not applicable1 country
- Late Subclinical Cardiovascular Disease in Testicular Cancer SurvivorsRecruitingNCT056113071 country