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Postoperative Cognitive Complications clinical trials

The registry lists 260 studies for Postoperative Cognitive Complications across more than 10 countries. 55 are recruiting or about to start. 174 of them are mainly about Postoperative Cognitive Complications (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
129
Status unknown
50
Recruiting
33
Not yet recruiting
21
Active, not recruiting
13
Terminated
11

Phase

Phase 4
27
Phase 2
10
Phase 3
9
Phase 1
2
Early Phase 1
1

Where

China
57
United States
35
Turkey
32
Germany
9
Egypt
8
Italy
7

Who runs them

RenJi Hospital (8) · University Hospital, Basel, Switzerland (6) · General Hospital of Ningxia Medical University (6) · Icahn School of Medicine at Mount Sinai (5) · Heart and Brain Research Group, Germany (4) · Osijek University Hospital (4) · Beni-Suef University (3) · University of Michigan (3)

What is being tested here

Drugs under test in Postoperative Cognitive Complications studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Propofol207
Desflurane206
Remimazolam212
Dexmedetomidine1010
Sevoflurane106
Ketamine106
Ciprofol102
Daridorexant102
Midazolam112
Ibuprofen101

Drug classes tested here Inhaled anesthetics 3 open · Local anesthetics 4

Coming up

2phase 3 studies under way
18studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 33 Postoperative Cognitive Complications studies recruiting now, 21 (64%) set no upper age limit and 4 (12%) stop at 75 or younger. 2 (6%) take children under 18. 2 (6%) are for women only and 0 (0%) for men only; 6 (18%) take healthy volunteers.

Recruiting studies that take each age, of 33
AgeWomenMen
101 (3%)1 (3%)
1814 (42%)12 (36%)
3014 (42%)12 (36%)
4014 (42%)12 (36%)
5013 (39%)12 (36%)
6530 (91%)29 (88%)
7530 (91%)29 (88%)
8527 (82%)26 (79%)

Across all 260 studies, recruiting or not: 16% stop at 75 or younger and 9% at 65; 3% take children; 2% are for women only and 2% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Postoperative Cognitive Complications studies take

Of 76 observational studies under Postoperative Cognitive Complications, half reached primary completion within 27 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase16 mo8–33 · 62 studies—16 mo8–33 · 62 studies
Observational27 mo11–65 · 76 studies—27 mo11–65 · 76 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 260. Browse all 260 → or search them.