Liver Failure clinical trials
The registry lists 445 studies for Liver Failure across more than 10 countries. 69 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 220
- Status unknown
- 96
- Recruiting
- 37
- Not yet recruiting
- 29
- Terminated
- 25
- Withdrawn
- 20
Phase
- Phase 1
- 102
- Phase 2
- 65
- Phase 4
- 22
- Phase 3
- 21
- Early Phase 1
- 3
Where
- United States
- 94
- China
- 80
- India
- 58
- Germany
- 26
- France
- 24
- United Kingdom
- 21
Who runs them
Institute of Liver and Biliary Sciences, India (41) · Third Affiliated Hospital, Sun Yat-Sen University (15) · Merck Sharp & Dohme LLC (14) · Post Graduate Institute of Medical Education and Research, Chandigarh (11) · Nanfang Hospital, Southern Medical University (11) · Boehringer Ingelheim (10) · Assistance Publique - Hôpitaux de Paris (10) · Sun Yat-sen University (8)
Studies
Recruiting first, then most recently updated. Showing 50 of 445 — search for more.
- Empagliflozin in Patients With Cirrhosis and AscitesRecruitingNCT05726032Phase 21 country
- Role of N-Acetylcysteine in Non-Acetaminophen-Induced Liver FailureRecruitingNCT07765823Not applicable1 country
- CT Volumetry and Hepatic Vascular Deformation Mapping to Predict Post-Hepatectomy Liver FailureRecruitingNCT077277591 country
- TLI- and ATG-Enabled Minimization Protocol in Liver TransplantationNot yet recruitingNCT07634562Phase 1/21 country
- Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver ImpairmentRecruitingNCT04617522Phase 14 countries
- VitaSmart HOPE System: Bridge to HOPE RegistryEnrolling by invitationNCT075784411 country
- Hypothermic Machine Perfusion for Liver Graft PreservationNot yet recruitingNCT07595627Not applicable1 country
- Personalized Two-stage Regional Citrate Anticoagulation for CRRT in Patients With Citrate Metabolism ImpairmentNot yet recruitingNCT07579663Not applicable
- Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size SyndromeRecruitingNCT07312864Phase 1/21 country
- Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver FailureRecruitingNCT06904755Phase 11 country
- A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)RecruitingNCT063660481 country
- Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot StudyRecruitingNCT066191061 country
- Glucocorticoids for Acute Drug Induced Liver Injury With HyperbilirubinemiaRecruitingNCT06922669Not applicable1 country
- The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) TrialRecruitingNCT06871111Phase 11 country
- National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Phase I Study on Safety and Efficacy of Mesenchymal Stem-Cell (MSC) Therapy in Non-Viral Acute-on-Chronic Liver Failure (ACLF)Not yet recruitingNCT07131540Phase 1
- CRISPR-Edited HLA Donor Liver Transplant to Reduce RejectionRecruitingNCT07053488Phase 1/21 country
- Non-selective Beta-blocker in Compensated Advanced Chronic Liver DiseaseRecruitingNCT06449339Phase 41 country
- Perioperative Use of Amino Acids in Recipients of Orthotopic Liver Transplantation as a Renal Protective FactorNot yet recruitingNCT07004387Not applicable1 country
- Efficacy and Safety of Citrate Anticoagulation in CRRT for Patients With Liver Failure/DysfuncTION, the CAUTION Trial! A Retrospective Study on Etiology of Liver Failure and Their ComplicationsRecruitingNCT069087461 country
- Clinical Study of Pediatric Acute Liver FailureEnrolling by invitationNCT068930421 country
- Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating ACLFNot yet recruitingNCT06884904Phase 2/3
- Single Cell Landscape of HBV-related Acute-on-chronic Liver Failure PatientsRecruitingNCT068658591 country
- The Safety ,Tolerability and Efficacy Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver FailureRecruitingNCT05989958Phase 1/21 country
- Study About Hepatic Toxins Kinetic and Evaluation of Organ Damage in Acute on Chronic Liver Failure (ACLF) PatientsRecruitingNCT068377661 country
- MSC-EVs in Acute/ Acute-on-Chronic Liver Failure After Liver TransplantationNot yet recruitingNCT06825572Phase 11 country
- Comparison of Efficacy and Safety of Ceftazidime Avibactam Versus Extended Infusions of High Dose Meropenem in Patients of ACLF With Nosocomial Infections.Not yet recruitingNCT06818565Not applicable1 country
- Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal BleedNot yet recruitingNCT06815770Phase 2/31 country
- Etiology and Prognostic Analysis of Acute Liver Failure in Chinese ChildrenNot yet recruitingNCT06778941
- Study of Oxidized Albumin in Liver Transplant PatientsNot yet recruitingNCT06772298
- Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLFRecruitingNCT03920618Not applicable1 country
- Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCCRecruitingNCT05484908Not applicable1 country
- Combination of DPMAS and Low Volume PE for Patients With HBV Related ACLFRecruitingNCT045971641 country
- Daily Versus Alternate Day Plasma Exchange in Wilson Disease With Acute Liver Failure in ChildrenNot yet recruitingNCT06698991Not applicable1 country
- Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant PatientsRecruitingNCT057446352 countries
- Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver FailureRecruitingNCT062240231 country
- Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney Injury in Acute on Chronic Liver Failure With Septic ShockNot yet recruitingNCT06556472Not applicable1 country
- Clinical Retrospective Study Analysis of Postoperative Complications Following HepatectomyRecruitingNCT065322141 country
- Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal InfectionRecruitingNCT064370671 country
- Human Umbilical Cord Mesenchymal Stem Cell Transplantation for The Treatment of Acute-on-Chronic Liver FailureRecruitingNCT05985863Phase 1/21 country
- To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.Not yet recruitingNCT063871601 country
- To Optimize Therapeutic Procedures of DPMAS in ACLF Patients: a Prospective, Sigle Arm and Multicenter StudyNot yet recruitingNCT06377774
- Validation of a Prognostic Score for Steroid Therapy Response in Acute Severe Autoimmune HepatitisNot yet recruitingNCT05473403Not applicable1 country
- Fecal Microbiota Transplantation for Liver FailureRecruitingNCT05170971Not applicable1 country
- Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF PatientsNot yet recruitingNCT062986561 country
- A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With InfectionNot yet recruitingNCT06272071
- An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment ResponseNot yet recruitingNCT06276907Not applicable1 country
- Usability and Clinical Effectiveness of an Interpretable Deep Learning Framework for Post-Hepatectomy Liver Failure PredictionRecruitingNCT060318181 country
- Individual Nutrition Support in HBV-ACLF Patients at Nutrition RiskRecruitingNCT06128421Not applicable1 country
- Throid Dysfunction in Liver Failure and Its Eddects Upon OutcomeRecruitingNCT061793681 country
- Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver FailureNot yet recruitingNCT06190002