Shock, Cardiogenic clinical trials
The registry lists 296 studies for Shock, Cardiogenic across more than 10 countries. 134 are recruiting or about to start. 221 of them are mainly about Shock, Cardiogenic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
Central Hospital, Nancy, France (12) · Assistance Publique - Hôpitaux de Paris (8) · Beijing Anzhen Hospital (7) · University Hospital, Montpellier (7) · Samsung Medical Center (6) · Abiomed Inc. (6) · University Hospital, Strasbourg, France (5) · National Taiwan University Hospital (4)
What is being tested here
Drugs under test in Shock, Cardiogenic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic Shock · Phase 3 · Pr Bruno LEVY
- Mar 2027Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function. · Phase 3 · Central Hospital, Nancy, France
- May 2027Ivabradine in the Acute Management of Cardiogenic Shock · Phase 3 · National Institute of Cardiovascular Diseases, Pakistan
- Nov 2026Genomic Determinants of Outcome in Cardiogenic Shock · Barts & The London NHS Trust
- Nov 2026Pilot Italian Cardiogenic Shock Initiative · Fondazione GISE Onlus
- Dec 2026CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock · Ottawa Heart Institute Research Corporation
- Dec 2026A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care. · 4TEEN4 Pharmaceuticals GmbH
- Dec 2026Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock · Henry Ford Health System
- Dec 2026Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients · First Affiliated Hospital of Wannan Medical College
- Dec 2026PRecision Ecmo in CardIogenic Shock Evaluation · Australian and New Zealand Intensive Care Research Centre
Who these studies take
Of the 102 Shock, Cardiogenic studies recruiting now, 70 (69%) set no upper age limit and 9 (9%) stop at 75 or younger. 11 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (2%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 11 (11%) | 11 (11%) |
| 18 | 93 (91%) | 93 (91%) |
| 30 | 100 (98%) | 100 (98%) |
| 40 | 101 (99%) | 101 (99%) |
| 50 | 101 (99%) | 101 (99%) |
| 65 | 100 (98%) | 100 (98%) |
| 75 | 98 (96%) | 98 (96%) |
| 85 | 79 (77%) | 79 (77%) |
Across all 296 studies, recruiting or not: 11% stop at 75 or younger and 3% at 65; 10% take children; 1% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Shock, Cardiogenic studies take
Of 84 observational studies under Shock, Cardiogenic, half reached primary completion within 45 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 39 mo24–55 · 53 studies | — | 39 mo24–55 · 49 studies |
| Observational | 45 mo24–… · 84 studies | — | 44 mo19–… · 79 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting6
- Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic ShockNov 9, 2026NCT07762560
- Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO AlgorithmNov 5, 2026NCT07484828
- CRP Apheresis in Infarct-Related Cardiogenic ShockOct 27, 2026NCT07687017
- Routine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory SupportOct 23, 2026NCT07482865
- Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic ShockOct 15, 2026NCT07562932
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Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 296. Browse all 296 → or search them.
- Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic ShockRecruitingNCT07762560Not applicable1 country
- Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO AlgorithmRecruitingNCT074848281 country
- Hemodynamic Evaluation of Left Atrial Pressure in Relationship to Pulmonary Capillary Wedge Pressure in Cardio Thoracic PatientsNot yet recruitingNCT07163052
- Capital Offload-ShockNot yet recruitingNCT07756801Phase 41 country
- CRP Apheresis in Infarct-Related Cardiogenic ShockRecruitingNCT07687017Not applicable1 country
- Cardiogenic Shock Working Group RegistryRecruitingNCT046824831 country
- Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic ShockRecruitingNCT069646851 country
- Changes in Skeletal Muscle Thickness in Patients With Acute Heart FailureRecruitingNCT062531041 country
- Routine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory SupportRecruitingNCT07482865Not applicable1 country
- Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone DynamicsRecruitingNCT078856181 country
- CytOSorb TreatMent Of Critically Ill PatientS RegistryRecruitingNCT051463366 countries
- Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic ShockRecruitingNCT07562932Not applicable1 country
- INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac RecoveryRecruitingNCT06965504Not applicable1 country
- French Observatory on the Management of Cardiogenic Shock 2Not yet recruitingNCT078687571 country
- Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic ShockRecruitingNCT07345559Not applicable1 country
- Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic ShockRecruitingNCT07583446Phase 2/31 country
- Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill PatientsNot yet recruitingNCT07184593
- Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMORecruitingNCT05699005Phase 11 country
- Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic ShockRecruitingNCT078253631 country
- Hong Kong Cardiogenic Shock InitiativeNot yet recruitingNCT073232381 country
- A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care.RecruitingNCT06832722Phase 1/29 countries
- Optimal Timing of Microaxial Flow Pump(Impella CP) in AMI-related Cardiogenic ShockNot yet recruitingNCT07817472Not applicable1 country
- Cardiac Rehabilitation in Patients Acutely Managed for Cardiogenic Shock (ENIGMA)RecruitingNCT065728261 country
- Catheter-Oriented Unloading and Recovery With a Left Ventricular Assist Gear: Efficacy in Post Cardiotomy Cardiogenic ShockRecruitingNCT07560085Not applicable1 country
- Rapid Microaxial Flow Pump Support and Escalation in Patients With Myocardial Infarction Associated Cardiogenic Shock and Persistent Need of Hemodynamic SupportRecruitingNCT076554791 country
- Efferon CT Hemoadsorption for Cardiogenic Shock in Acute Myocardial InfarctionRecruitingNCT06955936Not applicable1 country
- Empagliflozin's Microcirculatory Effects in Cardiogenic Shock: an Ancillary Pilot Study of the EMPASHOCK TrialRecruitingNCT07141355Not applicable1 country
- Impella Reverse Remodeling in End-Stage Heart FailureRecruitingNCT068007161 country
- Prognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients.Not yet recruitingNCT077735971 country
- Safety and Efficacy of the Extracorporeal Ventricular Assist System in Car Diogenic Shock: A Prospective, Multicenter , Single-Arm StudyRecruitingNCT07769528Not applicable1 country
- CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic ShockNot yet recruitingNCT07461961Phase 21 country
- Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemRecruitingNCT06080074Phase 21 country
- COMPARE-VENT Feasibility Pilot StudyRecruitingNCT07656259Not applicable1 country
- Cardiac Power Output in Cardiogenic Shock PatientsRecruitingNCT05700617Early Phase 11 country
- Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurERecruitingNCT075155081 country
- Ivabradine in the Acute Management of Cardiogenic ShockRecruitingNCT07714746Phase 31 country
- Magenta Elevate™ Clinical Feasibility Study in Cardiogenic ShockRecruitingNCT07293923Not applicable2 countries
- Digital Out-of-hospital Management on Clinical Outcomes in Patients With Early Cardiogenic ShockRecruitingNCT07085221Not applicable1 country
- Abiomed Impella RT-DAQ - Observational StudyRecruitingNCT063080553 countries
- Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)RecruitingNCT075972911 country
- BEAT-SHOCK RegistryRecruitingNCT076436101 country
- OPTIMIZE 5.5 - Optimizing Impella 5.5 Outcomes Through Advanced Data ScienceRecruitingNCT076191441 country
- Oxygen Delivery Index (ODIN) StudyNot yet recruitingNCT07601828Not applicable
- Altshock-2 REGISTRYRecruitingNCT042952521 country
- Feasibility of Protocolised Analgosedation in ECMONot yet recruitingNCT07580781Not applicable1 country
- Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation ProtocolRecruitingNCT070329871 country
- Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic ShockRecruitingNCT05298124Not applicable2 countries
- CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic ShockRecruitingNCT05267886Phase 42 countries
- Physiology of Unloading VA ECMO TrialRecruitingNCT06336655Phase 21 country
- Transcatheter AortiC Valve Implantation in aorTic stenosIs CardiogenIc ShockRecruitingNCT06638268Not applicable1 country