Shock, Septic clinical trials
The registry lists 863 studies for Shock, Septic across more than 10 countries. 209 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 395
- Status unknown
- 152
- Recruiting
- 119
- Not yet recruiting
- 85
- Terminated
- 53
- Withdrawn
- 27
Phase
- Phase 2
- 123
- Phase 3
- 116
- Phase 4
- 71
- Phase 1
- 29
- Early Phase 1
- 1
Where
- France
- 156
- United States
- 122
- China
- 66
- Egypt
- 54
- Germany
- 45
- Italy
- 41
Who runs them
Assistance Publique - Hôpitaux de Paris (20) · Southeast University, China (15) · Cairo University (14) · Hospices Civils de Lyon (14) · Assiut University (13) · Centre Hospitalier Universitaire, Amiens (12) · Mahidol University (11) · Ain Shams University (10)
Studies
Recruiting first, then most recently updated. Showing 50 of 863 — search for more.
- Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic ShockNot yet recruitingNCT06746753Phase 41 country
- Myeloid Bias in the Bone Marrow of Septic Patients and Its Correlation With Disease Severity and Prognosis: A Single-Center, Prospective Cohort StudyNot yet recruitingNCT07667153
- Prognostic Power of the VEXUS Score in Septic Shock: Effectiveness in Mortality PredictionRecruitingNCT071247411 country
- Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill PatientsNot yet recruitingNCT07184593
- Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic ShockRecruitingNCT04494074Not applicable1 country
- PRIME Sepsis Trial: Early Sepsis Detection in the Emergency Department Using Presepsin and Immature GranulocytesNot yet recruitingNCT078224121 country
- Protocolized Reduction of Non-resuscitation Fluids Versus Usual Care in Septic Shock PatientsRecruitingNCT06140147Not applicable3 countries
- Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive VentilationRecruitingNCT07530146Phase 31 country
- Early Optimization of Ceftazidime Regimen in Critical CareNot yet recruitingNCT07085624Not applicable1 country
- Angiotensin II Stress Test. Renin Kinetics During Treatment of Vasoplegic Shock With Angiotensin II.RecruitingNCT065392341 country
- Dynamic POCUS of Diaphragm Function to Predict Respiratory Failure in Septic ShockNot yet recruitingNCT078202671 country
- Microbiology Operations & Time Optimization in SepsisNot yet recruitingNCT078170431 country
- Ionized Calcium as a Severity Marker in Septic Shock PatientsNot yet recruitingNCT07812051
- Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care UnitNot yet recruitingNCT07811180Not applicable1 country
- Early Endotoxin Burden Reduction With oXiris in Septic Shock Patients Requiring CRRTRecruitingNCT07807410Not applicable1 country
- Early Angiotensin II in the Emergency DepartmentRecruitingNCT06693726Phase 41 country
- Extended vs. Intermittent Meropenem Infusion in Sepsis Patients in the ICUNot yet recruitingNCT07398703
- This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume OverloadNot yet recruitingNCT07797751
- Early Versus Late Adjunctive Vasopressin in Septic ShockRecruitingNCT06709573Phase 41 country
- NAI (Nogapendekin Alfa Inbakicept) Plus Standard of Care in Critically Ill Adults With SepsisNot yet recruitingNCT07783789Phase 1/2
- Personalized Fluid Resuscitation in the Emergency Department: A Pilot TrialRecruitingNCT07779720Not applicable1 country
- Plasma Exchange in Children With Severe Sepsis and Septic ShockRecruitingNCT07706413Not applicable1 country
- ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their CaregiversNot yet recruitingNCT07778004Not applicable1 country
- Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory FailureRecruitingNCT06881927Phase 41 country
- Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients With Septic CoagulopathyNot yet recruitingNCT07214103Phase 21 country
- Discordance Between Capillary Refill Time and Oxygen Extraction Ratio in Septic ShockRecruitingNCT077749621 country
- Dynamic SvO2 in Predicting Fluid Responsiveness in Septic ShockNot yet recruitingNCT075162361 country
- EEG Changes and Cognitive Profiles in Sepsis Patients With Different Inflammatory PhenotypesNot yet recruitingNCT077604151 country
- Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical StudyRecruitingNCT042886351 country
- Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter StudyNot yet recruitingNCT07746050Not applicable1 country
- Immune Dysregulation During Sepsis: A Natural History CohortNot yet recruitingNCT077357411 country
- Validation of a Capillary Leak Index During Septic Shock, Based on Haemoglobin Level Variations Induced by Fluid Resuscitation. A Pilot Study.Not yet recruitingNCT07733206Not applicable1 country
- Alterations of the Renin-angiotensin-aldosterone System in sEptic ShockNot yet recruitingNCT07721974Not applicable
- Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock PatientsNot yet recruitingNCT07716956Not applicable1 country
- Biological Effects of Hemoadsorption in Septic ShockNot yet recruitingNCT07715110Not applicable1 country
- Effects of Hemoadsorption on Vascular Integrity in Septic ShockNot yet recruitingNCT07711197Not applicable1 country
- Comparison of Manual PAOP and Automatic PAOP (Smart Wedge)Not yet recruitingNCT07703592
- Albumin and Crystalloid Administration in Septic ShockRecruitingNCT05148286Phase 41 country
- ARTICE® Real Data Collection & Observational Trial, Phase 4 StudyRecruitingNCT073886281 country
- Effect of Adding Vasopressin on Cardiac Output, Blood Pressure, Diuresis, and Tissue Perfusion Indices in Patients With Septic ShockNot yet recruitingNCT076971441 country
- Septic Shock-induced ImmunosuppressionRecruitingNCT040676741 country
- Splanchnic Perfusion Monitoring in Septic Shock Using Doppler UltrasoundNot yet recruitingNCT07698834
- Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months Mortality After ICU Discharge for Patients Admitted for Septic Shock. The SIMS StudyRecruitingNCT07483710Not applicable1 country
- Characterizing Perfusion and Congestion Responses to Fluid Loading in Critically Ill Septic PatientsNot yet recruitingNCT076850021 country
- BioMArkeRs of INflammation, Infection, and Immunity in the Critical Area (MARINA): the Use of Inflammatory and Immunity Biomarkers as Early Predictors of Clinical Severity, Organ Damage, Response to Treatment, and Infectious Complications in Patients Admitted to the Critical Care Area.RecruitingNCT076827661 country
- Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety EvaluationNot yet recruitingNCT07661303Not applicable1 country
- Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot StudyRecruitingNCT074255871 country
- Papaverine and Sublingual Microcirculation in Septic ShockNot yet recruitingNCT07657741Not applicable1 country
- Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657702Not applicable1 country
- Effects of Esmolol on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657754Not applicable1 country