Drug
Nitroprusside clinical trials
Also written Nitropress and Nipruss.
Includes 2 studies of Sodium nitroprusside anhydrous.
- studies test it
- 36
- open now
- 4
- in phase 3
- 1
- first study started
- 1996
Keep track of what changes. Save the Nitroprusside studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
36 studies that test it; most in 2022 (4)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1999 | 2 |
| 2002 | 2 |
| 2003 | 2 |
| 2005 | 2 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 3 |
| 2011 | 1 |
| 2012 | 3 |
| 2014 | 1 |
| 2015 | 2 |
| 2017 | 1 |
| 2018 | 3 |
| 2019 | 2 |
| 2022 | 4 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 11
- Phase 2
- 12
- Phase 3
- 1
- Phase 4
- 3
- No phase
- 9
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 34
The University of Texas Medical Branch, Galveston (3) · Medical University of Vienna (2) · Emory University (2) · University of Missouri-Columbia (2) · The First Affiliated Hospital of Zhengzhou University (2) · Vicore Pharma AB (1) · University of Alberta (1) · The Emmes Company, LLC (1)
Often tested with
Tested in the same studies.
Acetylcholine (7) · Phenylephrine (4) · Norepinephrine (4) · Omega-N-Methylarginine (3) · Propranolol (2) · Phentolamine (2) · Isoproterenol (2) · Adenosine (2)
Studies
Open first, then newest update. How each study uses Nitroprusside is read from its arms, and is right about nine times in ten.
Testing it · 36
- : Vascular Function in Health and DiseaseRecruitingPhase 1D. Walter WrayNCT02966665Written as Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine
- Hot Flashes and Neurovascular Function in WomenRecruitingNot applicableMayo ClinicNCT05193968Written as Sodium Nitroprusside
- Role of Sympathetic Overactivity and Angiotensin II in PTSD and CVRecruitingPhase 2Emory UniversityNCT02560805Written as Sodium Nitroprusside (SNP)
- Early Neurovascular Adaptations in Aging WomenRecruitingEarly Phase 1University of Missouri-ColumbiaNCT06520982Written as Nitroprusside
- HeartPhone Cancer Survivors Trial 2019TerminatedPhase 1/2Penn State UniversityNCT03953326Written as Sodium Nitroprusside
- Sodium Nitroprusside in Early Course SchizophreniaTerminatedPhase 2Beth Israel Deaconess Medical CenterNCT04986072Written as Sodium Nitroprusside
- Effect of C21 on Forearm Blood FlowCompletedPhase 1Vicore Pharma ABNCT05277922Written as Sodium Nitroprusside
- Targeting ER Stress in Vascular DysfunctionTerminatedEarly Phase 1Colorado State UniversityNCT04001647Written as Sodium Nitroprusside
- Sex Differences in Sympathetic Vascular Reactivity at High AltitudeCompletedNot applicableUniversity of AlbertaNCT05525416Written as Sodium Nitroprusside
- Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating RoomCompletedPhase 2The Emmes Company, LLCNCT00135668Written as Nitroprusside
- The Pathophysiology of Orthostatic HypotensionCompletedPhase 1Vanderbilt University Medical CenterNCT00748059Written as phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine
- Ketamine and Nitroprusside for DepressionCompletedPhase 2Icahn School of Medicine at Mount SinaiNCT03102736Written as Nitroprusside
- Prevention of Coronary Slow Flow or No-Reflow During EPCI in Patients With Acute STEMIStatus unknownNot applicableThe First Affiliated Hospital of Zhengzhou UniversityNCT03406832Written as Nitroprusside Sodium
- Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart FailureWithdrawnPhase 4Montefiore Medical CenterNCT02767024Written as Sodium nitroprusside
- A Proof of Concept Study of Intravenous Sodium Nitroprusside in Adults With Symptomatic SchizophreniaCompletedPhase 2Massachusetts General HospitalNCT02164981Written as sodium nitroprusside
- Endothelial Hyperpolarization in HumansTerminatedPhase 2Emory UniversityNCT00166166Written as Sodium nitroprusside
- Role of Adenosine in the Release of VEGF and CytokinesTerminatedPhase 1Vanderbilt UniversityNCT00580905Written as Sodium Nitroprusside
- Prevention of Coronary Slow Flow or No-Reflow During PPCI in Patients With Acute STEMIStatus unknownNot applicableThe First Affiliated Hospital of Zhengzhou UniversityNCT03406819Written as Nitroprusside Sodium
- Nutritional and Contractile Regulation of Muscle GrowthCompletedPhase 1The University of Texas Medical Branch, GalvestonNCT00891696Written as Sodium nitroprusside
- Insulin and Sarcopenia in the ElderlyCompletedPhase 1The University of Texas Medical Branch, GalvestonNCT00690534Written as Sodium Nitroprusside
See all 36 studies that test Nitroprusside →
Given in every arm · 10 — Nitroprusside is usual care beside what is tested
- The Effect of Endothelin and L-Arginine on Racial Differences in VasoconstrictionCompletedPhase 1The University of Texas at ArlingtonNCT03679780Written as Sodium Nitroprusside
- Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)TerminatedPhase 2GlaxoSmithKlineNCT03446612Written as Sodium nitroprusside
- Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS)TerminatedPhase 4Cristália Produtos Químicos Farmacêuticos Ltda.NCT03743103Written as Nitroprusside, Sodium
- The Impact of Carbon Monoxide and Altitude on Vascular FunctionCompletedNot applicableUniversity of AlbertaNCT04928183Written as Sodium Nitroprusside
- Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise TrainingWithdrawnEarly Phase 1Colorado State UniversityNCT03972683Written as Sodium Nitroprusside
- Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young AdultsCompletedEarly Phase 1Colorado State UniversityNCT03738943Written as Sodium Nitroprusside
- The Effect of Antioxidants on Skin Blood Flow-BH4CompletedPhase 1The University of Texas at ArlingtonNCT03680573Written as Sodium Nitroprusside
- Bevacizumab and Endothelium Dependent VasodilationCompletedNot applicableRadboud University Medical CenterNCT01125943Written as Nitroprusside
- Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin UpregulationCompletedNot applicableUniversity of EdinburghNCT00901719Written as Sodium nitroprusside
- Interaction of Apelin and Angiotensin in the Human Forearm CirculationCompletedNot applicableUniversity of EdinburghNCT00901888Written as Sodium nitroprusside infusion
As the comparator · 2 — what is tested is compared with Nitroprusside
- Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in ObesityActive, not recruitingPhase 1Vanderbilt University Medical CenterNCT03318094Written as Sodium Nitroprusside
- Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP)CompletedPhase 3The Medicines CompanyNCT00093912Written as sodium nitroprusside
Codes
What other systems call Nitroprusside · ClinicalTrials.gg INT007903
- MeSH (NLM) D009599NitroprussideConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 169D1260KMNITROPRUSSIDEConfirmed FDA, NLM
- RxNorm 7476One source FDA
- NCI Thesaurus C77153NitroprussideOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009599 | Nitroprusside | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 169D1260KM | NITROPRUSSIDE | Confirmed FDA, NLM |
| RxNorm | 7476 | — | One source FDA |
| NCI Thesaurus | C77153 | Nitroprusside | One source FDA |
Also registered as sodium nitroprusside (UNII EAO03PE1TC · RxNorm 9895).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.