Sepsis clinical trials
The registry lists 1,887 studies for Sepsis across more than 10 countries. 457 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 901
- Status unknown
- 316
- Recruiting
- 264
- Not yet recruiting
- 172
- Terminated
- 94
- Withdrawn
- 60
Phase
- Phase 2
- 173
- Phase 3
- 156
- Phase 4
- 121
- Phase 1
- 73
- Early Phase 1
- 6
Where
- United States
- 394
- China
- 245
- France
- 179
- Germany
- 102
- Egypt
- 97
- United Kingdom
- 74
Who runs them
Assiut University (36) · Assistance Publique - Hôpitaux de Paris (32) · Ain Shams University (27) · Tanta University (18) · University of Florida (17) · Chinese PLA General Hospital (17) · Southeast University, China (17) · National Taiwan University Hospital (15)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,887 — search for more.
- NAI Plus Standard of Care Compared With Placebo Plus Standard of Care in Critically Ill Adults With SepsisNot yet recruitingNCT07783789Phase 2
- Molecular-based Optimization of Pathogen Identification in Sepsis Patients in the Indonesian National Referral HospitalRecruitingNCT07841535Not applicable1 country
- Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic ShockNot yet recruitingNCT06746753Phase 41 country
- Antibiotic Duration and Outcomes in High-Risk Febrile Neutropenia PatientsRecruitingNCT07372131Not applicable1 country
- Myeloid Bias in the Bone Marrow of Septic Patients and Its Correlation With Disease Severity and Prognosis: A Single-Center, Prospective Cohort StudyNot yet recruitingNCT07667153
- FMT for 90-Day Outcome of Clinical Use in ICU SepsisNot yet recruitingNCT07670299Not applicable
- A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the Participants With Sepsis Induced CoagulopathyRecruitingNCT06854640Phase 15 countries
- Immune Responses to Dengue and SepsisRecruitingNCT070402021 country
- Assessing Immune Dysfunction in SepsisRecruitingNCT071546151 country
- Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill PatientsNot yet recruitingNCT07184593
- Sepsis Associated Liver Injury in Pediatric Sepsis at Assiut University Children's Hospital - 2026Not yet recruitingNCT07832890
- Serial Platelet Count and Indices for Predicting In-Hospital Mortality in SepsisNot yet recruitingNCT07832903
- CLARITHROMYCIN TO PREVENT SECONDARY INFECTIONS IN PATIENTS WITH SEPSIS FOLLOWING LOWER RESPIRATORY TRACT INFECTIONS: THE CLASSIFY TRIALNot yet recruitingNCT07834346Phase 31 country
- Change in MAPSE During Treatment of SepsisRecruitingNCT056347331 country
- PRIME Sepsis Trial: Early Sepsis Detection in the Emergency Department Using Presepsin and Immature GranulocytesNot yet recruitingNCT078224121 country
- Temperature Optimization in Afebrile Septic PatienTsRecruitingNCT07831057Not applicable1 country
- STUDY00015328: Sepsis EndotypesEnrolling by invitationNCT031465461 country
- Curcumin in Critically Ill Patients With SepsisRecruitingNCT07436130Not applicable1 country
- Metabolic and Functional Study of γδ T Cells in Critically Ill PatientsRecruitingNCT076808161 country
- Early Optimization of Ceftazidime Regimen in Critical CareNot yet recruitingNCT07085624Not applicable1 country
- Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections: N-AcetylcysteineRecruitingNCT07273071Phase 41 country
- Microbiology Operations & Time Optimization in SepsisNot yet recruitingNCT078170431 country
- Immune Evaluation for Postoperative Sepsis-AKIEnrolling by invitationNCT078115441 country
- Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and SepsisRecruitingNCT06562803Not applicable1 country
- Detection of Neurological Manifestations Among Neonates With SepsisNot yet recruitingNCT07813689
- Multimodal Physiologic State Intelligence StudyEnrolling by invitationNCT078141181 country
- THE ROLE OF PANCREATIC STONE PROTEIN (PSP) AND PSP-GUIDED EARLY MEROPENEM TREATMENT TO MITIGATE SEPSIS RISK AT THE EMERGENCY DEPARTMENT: THE PROMISE DOUBLE BLIND, PHASE III, RANDOMIZED CONTROLLED CLINICAL TRIALNot yet recruitingNCT07813767Phase 31 country
- Ionized Calcium as a Severity Marker in Septic Shock PatientsNot yet recruitingNCT07812051
- The Potential of Mesenchymal Stromal Stem Cells to Correct Immune and Metabolic Dysfunctions in Circulating Immune Cells During Sepsis: An Ex Vivo Pilot Study.Not yet recruitingNCT078120121 country
- Development of Context-Adapted Quality Indicators for Early Sepsis Care in Sub-Saharan Africa - A Modified Delphi Consensus ProcedureRecruitingNCT077115351 country
- Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care UnitNot yet recruitingNCT07811180Not applicable1 country
- T6A Biomarker for Detection of Bacterial Infection in Newborn InfantsRecruitingNCT076706242 countries
- Hospital-Onset Sepsis Systematic Detection and Structured InterventionsNot yet recruitingNCT07804251Not applicable1 country
- Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).RecruitingNCT07489274Phase 42 countries
- Dexamethasone Treatment for Sepsis-associated Acute Respiratory Distress Syndrome: a Multicenter, Randomised, Double-blinded, Controlled TrialRecruitingNCT07576660Phase 31 country
- A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.RecruitingNCT07215702Phase 214 countries
- Pre-hospital Ventilation Clinical StudyEnrolling by invitationNCT056044301 country
- Extended vs. Intermittent Meropenem Infusion in Sepsis Patients in the ICUNot yet recruitingNCT07398703
- Senolytics To slOw Progression of Sepsis (STOP-Sepsis) TrialRecruitingNCT05758246Phase 21 country
- Plasma Neprilysin for Predicting Sepsis Within 48 Hours in ICU Patients With Infection or Suspected InfectionNot yet recruitingNCT077963861 country
- Dynamic Infection Kinetics for Early Diagnosis, Monitoring, and Prognostication of Sepsis in Adult Oncology Patients: Evaluating Serial Infection Biomarkers, Blood Culture Kinetics, Treatment Response, Disease Severity, and Clinical OutcomesRecruitingNCT077955021 country
- Early Versus Late Adjunctive Vasopressin in Septic ShockRecruitingNCT06709573Phase 41 country
- MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) TrialRecruitingNCT06319248Phase 21 country
- EARLY-SARDS: Early AlveolaR Lung biologY Underling Sepsis-Associated ARDSNot yet recruitingNCT072819111 country
- Oral Switch in Pediatric Bloodstream InfectionsNot yet recruitingNCT07791914Phase 41 country
- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket TrialRecruitingNCT06381661Phase 21 country
- EAA-Guided AN69-oXiris and PMX-HP Therapy in Septic PatientsEnrolling by invitationNCT07788144Not applicable1 country
- Personalized Fluid Resuscitation in the Emergency Department: A Pilot TrialRecruitingNCT07779720Not applicable1 country
- Plasma Exchange in Children With Severe Sepsis and Septic ShockRecruitingNCT07706413Not applicable1 country
- ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their CaregiversNot yet recruitingNCT07778004Not applicable1 country