Myocardial Ischemia clinical trials
The registry lists 1,123 studies for Myocardial Ischemia across more than 10 countries. 177 are recruiting or about to start. 421 of them are mainly about Myocardial Ischemia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 22 narrower conditions too, such as Coronary Artery Disease: 11,020 studies, 1,976 open.
ClinicalTrials.gov finds 11,061 studies for Myocardial Ischemia. How that becomes 1,121 here
This page counts the studies the registry files under Myocardial Ischemia, and those it files under no condition that list Myocardial Ischemiathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 11,061Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −9,484Filed under a narrower condition, counted on its own pageCoronary Artery Disease 4,362 · Myocardial Infarction 1,531 · Acute Coronary Syndrome 1,026 · Coronary Disease 958 · ST Elevation Myocardial Infarction 522 · Shock, Cardiogenic 234 · 16 more
- −5List Myocardial Ischemia as a condition, but the registry did not file them under itMost often written as “Silent Myocardial Ischemia” (2), “Chronic Myocardial Ischemia” (1), and “Perioperative Myocardial Ischemia” (1). The registry filed them under other conditions only, most often Diabetes Mellitus, Type 2 (2) and Ventricular Dysfunction, Left (1).
- −451Match it another way46 name it in the title, 3 in a keyword, and 402 by a synonym or other text the search reads.
- 1,121The count on this page26 of them list Myocardial Ischemia in their own words; the registry filed them under no condition.
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (60) · Abbott Medical Devices (44) · Fundación EPIC (19) · Medtronic Vascular (15) · Samsung Medical Center (13) · University of Aarhus (13) · Rigshospitalet, Denmark (13) · Yonsei University (10)
What is being tested here
Drugs under test in Myocardial Ischemia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 2 | 3 | 15 |
| Clopidogrel | 1 | 1 | 14 |
| Adenosine | 1 | 3 | 8 |
| Regadenoson | 1 | 0 | 8 |
| Ivabradine | 1 | 3 | 4 |
| Metoprolol | 1 | 1 | 3 |
| Colchicine | 1 | 0 | 2 |
| Flurpiridaz F-18 | 1 | 0 | 1 |
| Atenolol | 1 | 1 | 1 |
| Roxadustat | 1 | 0 | 1 |
Drug classes tested here NSAIDs 2 open · P2Y12 inhibitors 1 open · Beta blockers 1 open · Statins 8 · ACE inhibitors 6
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Innovative Care Pathway in Physical Activity and Behavior Change in Coronary Patients Post-cardiac Rehabilitation · Elsan
- Nov 2026Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS) · Medtronic Cardiac Ablation Solutions
- Nov 2026Essential Pro Study ( rEPIC04E-HK ) · Fundación EPIC
- Nov 2026Impact of Dynamic CoROnary RoADmap System for Guidance of Instantaneous Wave-Free Ratio or Fractional Flow Reserve · Yonsei University
- Nov 2026Evaluation of a Diagnostic Software for Coronary Artery Disease Using Retrospective CCTA Data (CODEX-1 Study) · Instituto de Investigación Biomédica de Salamanca
- Dec 2026Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation · University of Edinburgh
- Dec 20264-electrode ECG (DigitalCardio®) vs Standard 10-electrode ECG: Evaluating Ease of Use and Recording Quality · Clinique Bizet
- Dec 2026A Study to Evaluate the Safety and Pharmacokinetics of Regadenoson in Pediatric Patients · GE Healthcare
- Dec 2026Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II · AliveCor
- Dec 2026Quantitative Cardiac Parametric Mapping · Medical University of South Carolina
Who these studies take
Of the 135 Myocardial Ischemia studies recruiting now, 92 (68%) set no upper age limit and 6 (4%) stop at 75 or younger. 14 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 20 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 12 (9%) | 12 (9%) |
| 18 | 108 (80%) | 108 (80%) |
| 30 | 121 (90%) | 121 (90%) |
| 40 | 124 (92%) | 124 (92%) |
| 50 | 129 (96%) | 129 (96%) |
| 65 | 132 (98%) | 132 (98%) |
| 75 | 131 (97%) | 131 (97%) |
| 85 | 114 (84%) | 114 (84%) |
Across all 1,123 studies, recruiting or not: 14% stop at 75 or younger and 3% at 65; 9% take children; 2% are for women only and 3% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Myocardial Ischemia studies take
Of 21 phase 4 interventional studies under Myocardial Ischemia, half reached primary completion within 48 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 29 mo19–47 · 16 studies | — | — |
| Phase 3 | 40 mo21–51 · 17 studies | — | — |
| Phase 4 | 48 mo37–59 · 21 studies | — | — |
| Interventional, no phase | 34 mo15–58 · 192 studies | 34 mo14–58 · 37 studies | 33 mo15–56 · 155 studies |
| Observational | 40 mo21–90 · 204 studies | 27 mo16–40 · 39 studies | 51 mo23–127 · 165 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting4
- Randomized Prospective Trial on the Cost-Effectiveness of Photon-Counting CT Versus Energy-Integrating Detector CT in Suspected Chronic Coronary SyndromeNov 6, 2026NCT07831304
- Cardiovascular Acoustics for Early Disease DetectionOct 28, 2026NCT07496775
- Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study)Oct 22, 2026NCT07347197
- Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)Oct 16, 2026NCT07095634
Results posted1
Newly registered3
- Implementation, Safety, and Effectiveness of Outpatient Cardiac Telerehabilitation in Patients With Ischemic Heart DiseaseNov 10, 2026NCT07927829
- Comparison Between Different Insulin Resistance Markers and Their Correlation With Severity of Coronary Artery Disease in Non-diabetic Patients.Nov 10, 2026NCT07928336
- Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass SurgeryNov 3, 2026NCT07912801
Studies
Recruiting first, then most recently updated. Showing 50 of 1,123. Browse all 1,123 → or search them.
- Comparison Between Different Insulin Resistance Markers and Their Correlation With Severity of Coronary Artery Disease in Non-diabetic Patients.Not yet recruitingNCT079283361 country
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable4 countries
- Optical Coherence Tomography in Acute Vessel EvaluationEnrolling by invitationNCT07422688Not applicable12 countries
- The Influence of Modifying Highly Calcified Coronary Lesions on Coronary MicrocirculationEnrolling by invitationNCT06507449Not applicable1 country
- Implementation, Safety, and Effectiveness of Outpatient Cardiac Telerehabilitation in Patients With Ischemic Heart DiseaseRecruitingNCT07927829Not applicable1 country
- A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)RecruitingNCT07286578Not applicable4 countries
- Randomized Prospective Trial on the Cost-Effectiveness of Photon-Counting CT Versus Energy-Integrating Detector CT in Suspected Chronic Coronary SyndromeRecruitingNCT07831304Not applicable1 country
- Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass SurgeryNot yet recruitingNCT07912801Phase 41 country
- Use of GeriKit to Better Phenotype Older Adults With Ischemic Heart DiseaseRecruitingNCT05788666Not applicable1 country
- Cardiovascular Acoustics for Early Disease DetectionRecruitingNCT074967751 country
- Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)RecruitingNCT07585968Not applicable1 country
- Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial FibrillationRecruitingNCT069511001 country
- Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study)RecruitingNCT07347197Phase 1/21 country
- Comparison of an Ultra-low Strut Thickness Everolimus-eluting Biodegradable Polymer Stent Versus Durable Polymer Everolimus-eluting Stents in Patients Treated With Percutaneous Coronary InterventionRecruitingNCT06692140Not applicable1 country
- Coroflex® ISAR NEO PMCF StudyRecruitingNCT056987323 countries
- Cardiovascular Risk in Patients With IBDNot yet recruitingNCT07663201
- Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)RecruitingNCT070956341 country
- TOP-CABG Trial: Follow-up Extension (TOP-CABG FE)Not yet recruitingNCT07871591
- Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the AortaRecruitingNCT06705751Not applicable1 country
- Gangwon PCI Prospective RegistryRecruitingNCT020381271 country
- DAN-RELEASE - Reconsidering Long-Term Aspirin in the Elderly Patients With Stable Ischemic Heart DiseaseRecruitingNCT07795398Phase 41 country
- A Cluster-Randomized Controlled TrialNot yet recruitingNCT07845448Not applicable
- Spectroscopic Assessment of Myocardial Oxygenation Changes in Pediatric Heart SurgeryRecruitingNCT077851411 country
- Incidence and Outcome of Perioperative Myocardial Injury After Non-cardiac SurgeryRecruitingNCT025735321 country
- AI-enhanced Heart MRI for Evaluating Blood FlowNot yet recruitingNCT07833774
- LONG NAGOMI™ PMCF STUDYRecruitingNCT073990021 country
- 4-electrode ECG (DigitalCardio®) vs Standard 10-electrode ECG: Evaluating Ease of Use and Recording QualityRecruitingNCT07732283Not applicable1 country
- Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial ViabilityRecruitingNCT060470281 country
- Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD TrialNot yet recruitingNCT07382414Not applicable1 country
- Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)RecruitingNCT06703489Not applicable1 country
- Pulsed Field Ablation for Post-Infarction Ventricular TachycardiaRecruitingNCT06891456Not applicable1 country
- Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPBRecruitingNCT06951308Not applicable1 country
- The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States StudyRecruitingNCT06854458Not applicable1 country
- Efficacy of Multiple Nerve Blocks on the Recovery of Patients Undergoing Off Pump CABG SurgeriesRecruitingNCT07794527Not applicable1 country
- Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care PathwaysEnrolling by invitationNCT077759761 country
- Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart DiseaseNot yet recruitingNCT00117936Phase 2
- Hyperemic mYocardial Perfusion by adEnosine at diffeRent DosesRecruitingNCT06578234Phase 41 country
- Ultrathin Strut Sirolimus-eluting Stent With Bioabsorbable Polymer in Patients Receiving Chronic Oral AnticoagulationRecruitingNCT068631551 country
- Longitudinal Validation of CIRC TechnologiesRecruitingNCT070817111 country
- Multimodal mAgnetic Resonance imaGIng in Cardiovascular DiseaseRecruitingNCT076178441 country
- Revascularization of Calcified Coronary ArteriesRecruitingNCT077241841 country
- Revascularization Versus Optimal Medical Therapy of Chronic Total Coronary Occlusions on Left Ventricular Ischemia ReductionRecruitingNCT03756870Not applicable1 country
- QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled TrialRecruitingNCT07635407Not applicable1 country
- MCG for Non-Obstructive Myocardial IschemiaRecruitingNCT076575461 country
- Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABGRecruitingNCT07192211Phase 21 country
- Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease HistoryRecruitingNCT05867381Not applicable1 country
- AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable MonitorRecruitingNCT066990561 country
- International Multicenter Project Comparing Radiofrequency Ablation Versus Implantable Defibrillator After Well-tolerated Ventricular Tachycardia in Ischemic Heart Disease With Minimally Impaired Ejection FractionRecruitingNCT06294028Not applicable1 country
- Exercise Echocardiography Registry for Ischemic and Non-Ischemic Heart DiseaseRecruitingNCT073678931 country
- Acolyte CTO-PCI Study: Imaging and Catheter System to Treat Patients With Coronary Chronic Total Occlusion, Who Have Persistent Symptoms Following Medical Therapy and Are Undergoing Percutaneous Coronary Interventional ProceduresEnrolling by invitationNCT06795763Not applicable1 country