ClinicalTrials.gg
RecruitingNCT02855554MyomappingUpdated Nov 5, 2025

Quantitative Cardiac Parametric Mapping

An interventional study of Cardiac Magnetic Resonance (CMR) imaging techniques in Cardiomyopathy, Myocarditis, Ischemic Heart Disease, sponsored by Medical University of South Carolina. Recruiting at 1 site in United States. Open to participants aged 18 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-11-05.

Primary conditionMyocarditisRegistry: CardiomyopathiesReclassifiedWhy we changed it
Registry
Cardiomyopathies — the first condition term the registry derived for this study.
ClinicalTrials.gg
Myocarditis
Why
  1. The study's listed conditions name Myocarditis, a narrower term within Cardiomyopathies.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Medical University of South Carolina · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
240
Allocation
Not applicable
Ages
18 Years to 90 Years
Sex
All
01

Study summary

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

02

Conditions studied

  • Cardiomyopathy, Myocarditis, Ischemic Heart Disease

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Keywords

  • myocardial tissue characterization
03

In context

Myocarditis Reclassified

174 studies on the registry are indexed under Myocarditis; 75 are open to participants now.

This study's planned enrollment of 240 is above the median of 80 across 53 interventional studies indexed under Myocarditis.

Browse Myocarditis studies →

Lead sponsor

Medical University of South Carolina is the lead sponsor of 874 studies on the registry; 166 are open to participants now.

Of its 131 completed or terminated interventional studies of FDA-regulated products, 104 (79%) have results posted.

Compared within Myocarditis, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Cardiomyopathies. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Subject must be 18-90 years of age.
  • Subject must be previously diagnosed with or suspected to have one of the following conditions.
  • Myocardial ischemia or infarction (group 1)
  • Hypertrophic cardiomyopathy (group 2)
  • Infiltrative cardiomyopathy (group 3)
  • Myocarditis (group 4)
  • Subject must have been referred for a clinically indicated CMR.

Exclusion criteria

Exclusion Criteria:

  • Subject has any implanted device or condition in which an MR scan would be .
  • Subject has an acute psychiatric disorder or is cognitively impaired.
  • Subject is using or is dependent on substances of abuse.
  • Subject is unwilling to comply with the requirements of the protocol.
  • Subject has previously entered this study.
  • Subject has an allergy against MRI contrast agents.
  • Subject is in acute unstable condition.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
240 participants (estimated)

Study arms

  • Experimental
    Additional 5 minute research MR scan of heart.

    The purpose of this is to evaluate new, faster MR scans

    Other: Cardiac Magnetic Resonance (CMR) imaging techniques

Interventions

  • OtherCardiac Magnetic Resonance (CMR) imaging techniques

    Evaluation of clinical potential of fast quantitative myocardial tissue characterization using recently emerged CMRI techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases.

06

What researchers measure

Primary outcomes

  1. Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.

    Time frame: 2 years

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jun 2014, a primary completion of Dec 2026 and a completion of Dec 2026. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 28, 2016
First posted
Aug 4, 2016
Start
Jun 20, 2014
Primary completionEst.
Dec 2026
CompletionEst.
Dec 2026
Last update
Nov 5, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Nov 5, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02855554
Responsible party
Sponsor
First posted
Aug 4, 2016
Start date
Jun 20, 2014
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Nov 5, 2025

Study contacts

Mark Ghent, BA
Contact
ghent@musc.edu
843-876-7148
Jacob Rowe, BA
Contact
roweja@musc.edu
843-876-4922
Akos Varga-Szemes, MD
principal investigator · Medical University of South Carolina
View the source record on ClinicalTrials.gov ↗

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