Acute Coronary Syndrome clinical trials
The registry lists 1,490 studies for Acute Coronary Syndrome across more than 10 countries. 272 are recruiting or about to start. 1,023 of them are mainly about Acute Coronary Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
ClinicalTrials.gov finds 1,985 studies for Acute Coronary Syndrome. How that becomes 1,488 here
This page counts the studies the registry files under Acute Coronary Syndrome, and those it files under no condition that list Acute Coronary Syndromethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,985Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −21List Acute Coronary Syndrome as a condition, but the registry did not file them under itMost often written as “Non ST Segment Elevation Acute Coronary Syndrome” (6), “Non-ST-elevation Acute Coronary Syndrome” (3), and “Acute Coronary Syndrome Without ST Elevation on Electrocardiogram” (2). The registry filed them under other conditions only, most often Angina, Unstable (5) and Non-ST Elevated Myocardial Infarction (4).
- −476Match it another way172 name it in the title, 2 in a keyword, and 302 by a synonym or other text the search reads.
- 1,488The count on this page25 of them list Acute Coronary Syndrome in their own words; the registry filed them under no condition.
Get an email when these change. Save the Acute Coronary Syndrome studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
AstraZeneca (35) · Massachusetts General Hospital (19) · Assistance Publique - Hôpitaux de Paris (19) · Assiut University (17) · Sohag University (13) · Yonsei University (13) · Wake Forest University Health Sciences (13) · Shenyang Northern Hospital (12)
What is being tested here
Drugs under test in Acute Coronary Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 7 | 3 | 26 |
| Ticagrelor | 5 | 16 | 60 |
| Colchicine | 4 | 3 | 13 |
| Inclisiran | 4 | 2 | 5 |
| Clopidogrel | 3 | 9 | 33 |
| Prasugrel | 2 | 13 | 31 |
| Rosuvastatin | 2 | 2 | 15 |
| Rivaroxaban | 2 | 2 | 13 |
| Evolocumab | 2 | 1 | 8 |
| Ezetimibe | 2 | 0 | 5 |
Drug classes tested here P2Y12 inhibitors 9 open · NSAIDs 7 open · Statins 4 open · Factor Xa inhibitors 2 open · PCSK9 inhibitors 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Efficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI) · Phase 3 · Jiangsu vcare pharmaceutical technology co., LTD
- Feb 2027Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes · Phase 3 · Novartis Pharmaceuticals
- Jun 2027Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Aug 2027triPle Oral thERapy With Bempedoic Acid vs uSual Care in Early Lipid Management of Patients With acUte coronAry synDromE · Phase 3 · Heart Care Foundation
- Aug 2027Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS · Phase 3 · DalCor Pharmaceuticals
- Nov 2026MPV as a Predictor for ACS in Patients With MASLD · Sohag University
- Nov 2026TIRANA-ACS: A Prospective Registry Study for the Targeted Investigation of Residual Inflammation After Non-ST/ ST Elevation Acute Coronary Syndrome · University Hospital Centre Mother Teresa
- Nov 2026Point-of-Care Troponin Testing in the Emergency Department · KU Leuven
- Nov 2026Tailoring Post Discharge - Remote Education and Access for Cardiac Health · St. Boniface Hospital
- Nov 2026Smartphone AI Assistance for Prehospital ECG Interpretation · École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care
Who these studies take
Of the 196 Acute Coronary Syndrome studies recruiting now, 145 (74%) set no upper age limit and 19 (10%) stop at 75 or younger. 15 (8%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 15 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 13 (7%) | 13 (7%) |
| 18 | 166 (85%) | 165 (84%) |
| 30 | 188 (96%) | 187 (95%) |
| 40 | 190 (97%) | 189 (96%) |
| 50 | 189 (96%) | 188 (96%) |
| 65 | 191 (97%) | 190 (97%) |
| 75 | 186 (95%) | 185 (94%) |
| 85 | 160 (82%) | 159 (81%) |
Across all 1,490 studies, recruiting or not: 12% stop at 75 or younger and 4% at 65; 7% take children; <1% are for women only and 1% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Acute Coronary Syndrome studies take
Of 92 phase 4 interventional studies under Acute Coronary Syndrome, half reached primary completion within 42 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 3 mo2–14 · 16 studies | — | — |
| Phase 2 | 28 mo17–39 · 30 studies | — | — |
| Phase 3 | 41 mo24–52 · 39 studies | — | — |
| Phase 4 | 42 mo26–60 · 92 studies | — | 45 mo27–67 · 85 studies |
| Interventional, no phase | 34 mo17–46 · 228 studies | — | 34 mo16–46 · 213 studies |
| Observational | 35 mo18–68 · 277 studies | 29 mo20–42 · 34 studies | 36 mo18–71 · 243 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting5
- AI-Assisted Interpretation of Cardiac CT in the Emergency DepartmentNov 5, 2026NCT07235657
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeNov 5, 2026NCT07684742
- CCTA Evaluation of SGLT2i-related Pericoronary Fat Changes Patients With Stage 4 CKM SyndromeOct 30, 2026NCT07351643
- Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese PopulationOct 27, 2026NCT06096909
- Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery DiseaseOct 20, 2026NCT07875088
Stopped2
- Comparison of Short Versus 12 Months Prasugrel Plus Aspirin in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention and Everolimus-eluting StentsTerminatedOct 22, 2026NCT06718179
- 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACSWithdrawnOct 19, 2026NCT06409117
Newly registered8
- Implementing the 6th Generation Cardiac Troponin TNov 13, 2026NCT07936630
- Motivational Interviewing for Smoking Cessation in Patients With Acute Coronary SyndromeNov 12, 2026NCT07933796
- The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitationNov 6, 2026NCT07921758
- Aspirin for the Prevention of Ischemic Complications in Giant Cell ArteritisOct 30, 2026NCT07908082
- Prognostic Value of Functional-Nutritional Status in Older Adults With Acute Coronary SyndromeOct 27, 2026NCT07898345
Show 3 moreShow fewer
- AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS)Oct 20, 2026NCT07882849
- Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery DiseaseOct 15, 2026NCT07875088
- Prevalence of CYP2C19 Genetic Polymorphisms Among Egyptian Patients Receiving Clopidogrel Following PCIOct 15, 2026NCT07876336
Studies
Recruiting first, then most recently updated. Showing 50 of 1,490. Browse all 1,490 → or search them.
- Implementing the 6th Generation Cardiac Troponin TRecruitingNCT07936630Not applicable2 countries
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable4 countries
- Optical Coherence Tomography in Acute Vessel EvaluationEnrolling by invitationNCT07422688Not applicable12 countries
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeRecruitingNCT07684742Phase 41 country
- AI-Assisted Interpretation of Cardiac CT in the Emergency DepartmentRecruitingNCT07235657Not applicable1 country
- CCTA Evaluation of SGLT2i-related Pericoronary Fat Changes Patients With Stage 4 CKM SyndromeRecruitingNCT07351643Phase 41 country
- Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care Alone for LDL-C Evaluation in Acute Coronary Syndrome Patients in Saudi ArabiaNot yet recruitingNCT07684469Phase 4
- Aspirin for the Prevention of Ischemic Complications in Giant Cell ArteritisNot yet recruitingNCT07908082Phase 31 country
- Prognostic Value of Functional-Nutritional Status in Older Adults With Acute Coronary SyndromeNot yet recruitingNCT078983451 country
- Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese PopulationRecruitingNCT06096909Phase 41 country
- Prevalence of CYP2C19 Genetic Polymorphisms Among Egyptian Patients Receiving Clopidogrel Following PCIEnrolling by invitationNCT078763361 country
- AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS)Not yet recruitingNCT078828491 country
- Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery DiseaseRecruitingNCT078750882 countries
- Fexuprazan for Prevention of Upper Gastrointestinal Bleeding in High Bleeding Risk Patients Receiving Dual Antiplatelet TherapyRecruitingNCT07479056Not applicable1 country
- Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) TrialNot yet recruitingNCT07683923Phase 45 countries
- Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable PlaquesRecruitingNCT06855537Phase 41 country
- IVUS-Guided Sirolimus-Coated Balloon Versus Sirolimus-Eluting Stent for De Novo Large Vessel Lesions in ACSNot yet recruitingNCT07796412Not applicable1 country
- Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)RecruitingNCT07721649Not applicable1 country
- Analysis of Life-threatening ARrhythMias After Acute Coronary SyndromeRecruitingNCT078240501 country
- Guideline Oriented Approach To Lipid Lowering In Asia-PacificRecruitingNCT05325034Not applicable9 countries
- CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACSRecruitingNCT07612774Phase 41 country
- Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comersRecruitingNCT07566091Not applicable1 country
- Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCIRecruitingNCT07846462Not applicable1 country
- CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)RecruitingNCT05897632Not applicable1 country
- Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate RecoveryRecruitingNCT070969731 country
- Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.RecruitingNCT071576701 country
- Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Followed by an Open-label Patient CohortRecruitingNCT06813339Early Phase 11 country
- A Polypill for Acute Coronary SyndromeRecruitingNCT07032389Phase 21 country
- Heart Failure-USB: Prediction and ProgressionRecruitingNCT040000611 country
- Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary SyndromeRecruitingNCT07824323Phase 41 country
- Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary SyndromesRecruitingNCT07102628Phase 314 countries
- "Discovery2" Study of Using MCG at Emergency DepartmentsNot yet recruitingNCT078225811 country
- Evaluation of a Musical Intervention on the Anxiety of Patients With a Diagnosis of Acute Coronary Syndrome in a Pre-Hospital Emergency Situation: MuSCA Randomized Controlled TrialRecruitingNCT06017947Not applicable1 country
- Non-Invasive Follow-Up of Patients With Coronary Artery Disease Treated With Drug-Coated Balloon PCI Using CT-Derived Fractional Flow ReserveNot yet recruitingNCT07811960
- Pre Hospital Triage of Patients at Intermediate and High Risk for ACSRecruitingNCT07252245Not applicable1 country
- Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation StudyRecruitingNCT07685639Not applicable1 country
- Smartphone AI Assistance for Prehospital ECG InterpretationRecruitingNCT07810686Not applicable1 country
- Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery DiseaseRecruitingNCT063279841 country
- Dual Antiplatelet Therapy Strategies After Acute Myocardial Infarction Undergoing PCI: Prasugrel vs Ticagrelor & 12 Months vs 1-3 MonthsRecruitingNCT07507500Phase 45 countries
- A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus BurdenRecruitingNCT078063701 country
- Florbetaben for Imaging of Vascular AmyloidRecruitingNCT060913191 country
- A Prospective Research Investigation of Ischemia Using MCGRecruitingNCT064819431 country
- Self-Management Support for Acute Coronary Syndrome Patients After Hospital DischargeNot yet recruitingNCT07799376Not applicable1 country
- Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment ElevationRecruitingNCT075639981 country
- Early Intensive Lipid-Lowering With Inclisiran for Plaque Stabilization in Acute Coronary SyndromeNot yet recruitingNCT07799779Phase 41 country
- Left Atrial Strain for Predicting MACE in NSTEMINot yet recruitingNCT07797634
- Effect of Guided Imagery on Sleep Quality, State Anxiety, and Comfort in Patients With Acute Coronary SyndromeNot yet recruitingNCT07794358Not applicable
- Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic TherapyRecruitingNCT04416581Phase 41 country
- Music Medicine in Coronary Interventional Cardiology ProceduresNot yet recruitingNCT07786961Not applicable1 country
- Tampere Coronary Artery Disease and Sudden Cardiac Arrest StudyRecruitingNCT068044991 country