Angina Pectoris clinical trials
The registry lists 453 studies for Angina Pectoris across more than 10 countries. 67 are recruiting or about to start. 156 of them are mainly about Angina Pectoris (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 4 narrower conditions too, such as Angina, Stable: 1,067 studies, 168 open.
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Status
Who runs them
CardioDx (11) · National Heart, Lung, and Blood Institute (NHLBI) (9) · Imperial College London (8) · Aarhus University Hospital Skejby (8) · University of Edinburgh (7) · Gilead Sciences (7) · Abbott Medical Devices (6) · China Academy of Chinese Medical Sciences (5)
What is being tested here
Drugs under test in Angina Pectoris studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Encoberminogene rezmadenovec | 1 | 0 | 2 |
| Amlodipine | 1 | 1 | 2 |
| Nebivolol | 1 | 1 | 2 |
| Bexagliflozin | 1 | 0 | 1 |
| Metoprolol | 1 | 0 | 1 |
| T89 | 1 | 1 | 1 |
| Ranolazine | 0 | 5 | 14 |
| Aspirin | 0 | 1 | 5 |
| Nitroglycerin | 0 | 0 | 5 |
| Ivabradine | 0 | 1 | 4 |
Drug classes tested here Beta blockers 3 open · Calcium channel blockers 2 open · Statins 9 · P2Y12 inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina · Phase 3 · Tasly Pharmaceuticals, Inc.
- Dec 2026Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries · Phase 3 · Stanford University
- Nov 2026"Erectile Function After PCI in MI and Non-MI Patients" · Kırıkkale University
- Nov 2026Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA · University of Virginia
- Dec 2026Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study · University of Leicester
- Dec 2026Development of a Novel Risk Prediction Tool for Emergency Department Patients Symptoms of Coronary Artery Disease · University of Calgary
- Dec 2026REGistry of Long-term AnTithrombotic TherApy-1 · National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
- Dec 2026SIROOP Registry - a Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated with SIROlimus or Paclitaxel Eluting Balloon Catheters · Luzerner Kantonsspital
- Jan 2027Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina · Imperial College London
- Feb 2027Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System · Biotronik AG
Who these studies take
Of the 46 Angina Pectoris studies recruiting now, 35 (76%) set no upper age limit and 1 (2%) stop at 75 or younger. 3 (7%) take children under 18. 3 (7%) are for women only and 1 (2%) for men only; 4 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (7%) | 3 (7%) |
| 18 | 41 (89%) | 39 (85%) |
| 30 | 43 (93%) | 42 (91%) |
| 40 | 43 (93%) | 42 (91%) |
| 50 | 44 (96%) | 42 (91%) |
| 65 | 45 (98%) | 43 (93%) |
| 75 | 45 (98%) | 43 (93%) |
| 85 | 44 (96%) | 41 (89%) |
Across all 453 studies, recruiting or not: 11% stop at 75 or younger and 2% at 65; 11% take children; 3% are for women only and 2% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Angina Pectoris studies take
Of 72 interventional studies with no phase under Angina Pectoris, half reached primary completion within 43 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 43 mo18–64 · 72 studies | — | 43 mo18–64 · 60 studies |
| Observational | 33 mo19–56 · 67 studies | 29 mo20–40 · 24 studies | 36 mo18–86 · 43 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCANov 9, 2026NCT06948201
Results posted1
- Benidipine in Hypertensive and/or Chronic Coronary Syndrome PatientsNov 4, 2026NCT06808321
Studies
Recruiting first, then most recently updated. Showing 50 of 453. Browse all 453 → or search them.
- Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCARecruitingNCT06948201Not applicable1 country
- Mental Stress Reactivity in Women With CMDRecruitingNCT05401630Not applicable1 country
- Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNginaRecruitingNCT06400290Not applicable1 country
- Study of Lesion-Specific Invasive Haemodynamic Angina ThresholdsRecruitingNCT07386418Not applicable1 country
- Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the AortaRecruitingNCT06705751Not applicable1 country
- Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathyNot yet recruitingNCT07865364Not applicable1 country
- Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT035813181 country
- Efficacy of the COronary SInus Reducer in Patients With Refractory Angina IIRecruitingNCT05102019Not applicable3 countries
- First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).RecruitingNCT07811024Not applicable1 country
- Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.RecruitingNCT07048808Phase 21 country
- Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)RecruitingNCT06600178Phase 11 country
- Diagnosis of Women With ANOCANot yet recruitingNCT078024571 country
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable2 countries
- Exercise Therapy for Women With ANOCANot yet recruitingNCT07733986Not applicable1 country
- TELEREHAB-BR: Cardiovascular Rehabilitation Models TrialNot yet recruitingNCT07734831Not applicable1 country
- Imaging Coronary Microvascular Dysfunction (CMD) StudyRecruitingNCT05634031Not applicable1 country
- Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell PropertiesRecruitingNCT063848461 country
- Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary AngiographyRecruitingNCT076381371 country
- CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)RecruitingNCT07165678Not applicable1 country
- AI-Enhanced Single-Lead ECG Screening for Coronary StenosisNot yet recruitingNCT075796241 country
- REGistry of Long-term AnTithrombotic TherApy-1RecruitingNCT043472001 country
- Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot StudyRecruitingNCT060706621 country
- Echocardiography: Value and Accuracy at REst and STressEnrolling by invitationNCT03674255
- Hybrid Exercise Program for Heart Disease: Effect on Health and Quality of LifeNot yet recruitingNCT07130045Not applicable1 country
- iCorMicA - Stratified Medicine in AnginaRecruitingNCT04674449Not applicable4 countries
- LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic ConditionsRecruitingNCT05786417Phase 41 country
- Angiography-Derived Physiological Indices for Outcome Prediction in Patients Undergoing OCT-Guided PCINot yet recruitingNCT075112311 country
- Coronary Sinus Reducer Therapy for Persisting AnginaNot yet recruitingNCT07485985Not applicable
- "Erectile Function After PCI in MI and Non-MI Patients"RecruitingNCT074446971 country
- Machine Learning in Quantitative Stress EchocardiographyRecruitingNCT041934751 country
- Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary CareRecruitingNCT07359287Not applicable1 country
- Coronary Imaging and Metabolic Indicators-Based Risk Prediction Model for Coronary Artery Disease(CMI-RiskCAD)Not yet recruitingNCT073537621 country
- Assessing the Safety and Effectiveness of Intracoronary Stem Cells in Patients With Refractory AnginaRecruitingNCT05711849Phase 21 country
- Personalized Evaluation of Susptected Myocardial IschemiaEnrolling by invitationNCT06708000Phase 31 country
- Breaking Fasts Ahead of Cardiac CathsRecruitingNCT06996639Not applicable1 country
- Perfusion Estimation For Optimal Treatment Strategy in Chronic Coronary SyndromeRecruitingNCT05865600Not applicable1 country
- Coronary Sinus Reducer in Coronary Microvascular DiseaseEnrolling by invitationNCT06898541Not applicable1 country
- Clinical Evaluation of Radiation Reduction for Optimized SafetyNot yet recruitingNCT063488751 country
- Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCARecruitingNCT06864234Phase 41 country
- Coronary Sinus Reducer in Patients With Angina With no Obstructive Coronary DiseaseRecruitingNCT07010029Not applicable1 country
- Development of a Novel Risk Prediction Tool for Emergency Department Patients Symptoms of Coronary Artery DiseaseNot yet recruitingNCT067436721 country
- Sirolimus With corTicOsteroid TheraPy for Rapid rEcurrences of Coronary Unexplained In-stent RestenosisNot yet recruitingNCT06981845Not applicable
- A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.Not yet recruitingNCT06945094
- Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable AnginaRecruitingNCT03789552Phase 31 country
- Angina After PCI: a Systems Medicine StudyEnrolling by invitationNCT068543021 country
- Nebivolol ANOCA Treatment Randomized TrialNot yet recruitingNCT06755801Phase 3
- Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery DiseaseRecruitingNCT04939207Not applicable1 country
- Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary ArteriesRecruitingNCT06424834Phase 2/31 country
- Efficacy of Endothelin Receptor Antagonism in Coronary Artery SpasmEnrolling by invitationNCT06432452Phase 2/31 country
- COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting with CompLEX and Calcified Coronary Artery DiseaseRecruitingNCT060756021 country