National Heart, Lung, and Blood Institute (NHLBI) clinical trials
Listed in the registry as: U.S. National Institutes of Health.
The registry lists 1,143 studies whose lead sponsor is National Heart, Lung, and Blood Institute (NHLBI). 72 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 23, 2026.
Keep track of what changes. Save the National Heart, Lung, and Blood Institute (NHLBI) studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
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Focus areas
Conditions National Heart, Lung, and Blood Institute (NHLBI) leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
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Studies
Recruiting first, then most recently updated. Showing 50 of 1,143. Browse all 1,143 →
- Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)Enrolling by invitationNCT06280820
- NHLBI-Emory Advanced Cardiac CT ReconstructionNot yet recruitingNCT05372627
- Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)RecruitingNCT02543996
- VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) CathetersEnrolling by invitationNCT06940752Not applicable
- Natural History of Acquired and Inherited Bone Marrow Failure SyndromesRecruitingNCT05012111
- Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesRecruitingNCT06948097Phase 1
- EDEN Intracardiac Electrogram Recording and Classifying SystemEnrolling by invitationNCT07137455Not applicable
- Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable
- Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 InhibitorNot yet recruitingNCT07796373Phase 2
- NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label DevicesNot yet recruitingNCT07806149Not applicable
- Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi)Not yet recruitingNCT07882173Phase 2
- Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy IndividualsRecruitingNCT07882160Not applicable
- Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesRecruitingNCT05213572
- Immune Profiling of CLL/SLL Treated With First-Line PirtobrutinibRecruitingNCT07428707Early Phase 1
- Data Collection of Standard Care and Evaluation of NHLBI Patients and DonorsEnrolling by invitationNCT04450927
- Blood Collection for Research Related to Certain Diseases Involving Blood VesselsEnrolling by invitationNCT00047996
- Natural History of Sickle Cell DiseaseRecruitingNCT00081523
- Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell DiseaseRecruitingNCT07566494Phase 1
- Improved Methods of Cell Selection for Bone Marrow Transplant AlternativesRecruitingNCT00001529
- Screening for Hematology Branch ProtocolsEnrolling by invitationNCT00001620
- Causes and Natural History of DyslipidemiasRecruitingNCT00353782
- Study of the Disease Process of LymphangioleiomyomatosisRecruitingNCT00001465
- Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cellsRecruitingNCT01174108Phase 2
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy VolunteersRecruitingNCT04216342Phase 1
- Role of Genetic Factors in the Development of Lung DiseaseRecruitingNCT00001532
- Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)RecruitingNCT00923507
- Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family MembersEnrolling by invitationNCT00071045
- Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research StudyEnrolling by invitationNCT07102849
- Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell TransplantsRecruitingNCT00106925
- Collection of Lung Fluid and Tissue Samples for ResearchRecruitingNCT00471250
- Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or VenetoclaxRecruitingNCT05724121
- Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy VolunteersRecruitingNCT00442195
- Genome Transplant DynamicsRecruitingNCT02423070
- Study of Skin Tumors in Tuberous SclerosisRecruitingNCT00001975
- Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood EnvironmentsRecruitingNCT03288207Not applicable
- Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruitingNCT01143454
- Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss InterventionRecruitingNCT01927783
- Partial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsRecruitingNCT07599176Phase 1/2
- Technical Development of Cardiovascular Magnetic Resonance ImagingRecruitingNCT04927429
- Immune Dysregulation During Sepsis: A Natural History CohortNot yet recruitingNCT07735741
- Evaluating New Radiation Techniques for Cardiovascular ImagingRecruitingNCT01621594Not applicable
- Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseRecruitingNCT05904093Phase 1
- Natural History Study of CADASILRecruitingNCT05072483
- Thrombosis and Inflammation in Vessels Initiative (TIVI)RecruitingNCT06552767
- Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruitingNCT07613099Phase 3
- Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT03581318
- Study of Intravenous ZMA001 in Healthy SubjectsRecruitingNCT05967299Phase 1
- Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)RecruitingNCT02417714
- Natural History of BronchiectasisRecruitingNCT00943514
- Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant OutcomeRecruitingNCT03173937Phase 1/2