Coronary Disease clinical trials
The registry lists 1,520 studies for Coronary Disease across more than 10 countries. 167 are recruiting or about to start. 828 of them are mainly about Coronary Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 8 narrower conditions too, such as Coronary Artery Disease: 6,373 studies, 1,064 open.
ClinicalTrials.gov finds 34,106 studies for Coronary Disease. How that becomes 1,520 here
This page counts the studies the registry files under Coronary Disease, and those it files under no condition that list Coronary Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 34,106Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −4,786Filed under a narrower condition, counted on its own pageCoronary Artery Disease 4,439 · Coronary Stenosis 125 · Coronary Restenosis 31 · Coronary Occlusion 28 · Coronary Aneurysm 25 · Coronary Vasospasm 20 · 2 more
- −22List Coronary Disease as a condition, but the registry did not file them under itMost often written as “Coronary Heart Disease Risk Reduction” (8), “Coronary Heart Disease NOS” (2), and “Non-obstructive Coronary Disease” (2). The registry filed them under other conditions only, most often Cardiovascular Diseases (9) and Heart Diseases (8).
- −27,778Match it another way131 name it in the title, 12 in a keyword, and 27,635 by a synonym or other text the search reads.
- 1,520The count on this page20 of them list Coronary Disease in their own words; the registry filed them under no condition.
Get an email when these change. Save the Coronary Disease studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (194) · Abbott Medical Devices (32) · China National Center for Cardiovascular Diseases (25) · Deutsches Herzzentrum Muenchen (23) · AstraZeneca (17) · Beijing Anzhen Hospital (13) · CardioDx (12) · Organon and Co (12)
What is being tested here
Drugs under test in Coronary Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 2 | 0 | 3 |
| Ticagrelor | 1 | 2 | 10 |
| Colchicine | 1 | 1 | 3 |
| Vitamin K 1 | 1 | 0 | 1 |
| PCSK9 Inhibitor | 1 | 0 | 1 |
| Thiamine | 1 | 0 | 1 |
| Resveratrol | 1 | 0 | 1 |
| Mazdutide | 1 | 0 | 1 |
| Olpasiran | 1 | 1 | 1 |
| Yangxinshi | 1 | 0 | 1 |
Drug classes tested here P2Y12 inhibitors 1 open · Statins 34 · NSAIDs 11 · ACE inhibitors 6 · Estrogens 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027One-Month DAPT in CABG Patients · Phase 3 · Weill Medical College of Cornell University
- Jun 2027Efficacy and Safety of Colchicine After PCI · Phase 3 · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Nov 2026Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions · Istanbul Mehmet Akif Ersoy Educational and Training Hospital
- Nov 2026Intelligent Management Platform for Guiding Exercise Rehabilitation in Coronary Heart Disease Patients · China National Center for Cardiovascular Diseases
- Dec 2026Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · Johns Hopkins University
- Dec 2026Real-World Effectiveness and Costs of Yiqi Fumai Lyophilized Injection in Coronary Heart Disease-Related Chronic Heart Failure · China Academy of Chinese Medical Sciences
- Dec 2026Vitamin K and Cognition in Coronary Heart Disease (NutriCog) · Montreal Heart Institute
- Dec 2026CORE-COMPARE Pilot Study · Johns Hopkins University
- Dec 2026Clinical Value and Cost-effectiveness of a Personalized Prevention Program (PPP) in Patients With High Risk Stable CHD · Tampere University
- Dec 2026Research on Optimal Diagnosis and Treatment of Cardiorenal Syndrome · Nanjing First Hospital, Nanjing Medical University
Who these studies take
Of the 106 Coronary Disease studies recruiting now, 64 (60%) set no upper age limit and 19 (18%) stop at 75 or younger. 8 (8%) take children under 18. 3 (3%) are for women only and 0 (0%) for men only; 10 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (8%) | 8 (8%) |
| 18 | 79 (75%) | 77 (73%) |
| 30 | 88 (83%) | 86 (81%) |
| 40 | 91 (86%) | 89 (84%) |
| 50 | 95 (90%) | 92 (87%) |
| 65 | 99 (93%) | 96 (91%) |
| 75 | 96 (91%) | 94 (89%) |
| 85 | 76 (72%) | 75 (71%) |
Across all 1,520 studies, recruiting or not: 20% stop at 75 or younger and 6% at 65; 18% take children; 3% are for women only and 10% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Coronary Disease studies take
Of 26 phase 4 interventional studies under Coronary Disease, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 17 mo10–39 · 19 studies | — | — |
| Phase 4 | 33 mo16–58 · 26 studies | — | — |
| Interventional, no phase | 25 mo14–51 · 200 studies | — | 26 mo15–51 · 178 studies |
| Observational | 47 mo21–123 · 154 studies | — | 59 mo24–192 · 132 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Newly registered4
- Out-Patient Proactive Observation With Wearable-Assisted Tracking for Cardiovascular Health ManagementNov 3, 2026NCT07912671
- Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation PatientsNov 2, 2026NCT07910812
- Superficial Parasternal Block Combined With Rectus Sheath Block for Open Cardiac SurgeryOct 22, 2026NCT07890857
- Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated DilationOct 20, 2026NCT07882550
Studies
Recruiting first, then most recently updated. Showing 50 of 1,520. Browse all 1,520 → or search them.
- Thiamine Intervention and Coronary Artery Bypass GraftingRecruitingNCT06326996Early Phase 11 country
- Out-Patient Proactive Observation With Wearable-Assisted Tracking for Cardiovascular Health ManagementNot yet recruitingNCT07912671Not applicable1 country
- Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation PatientsRecruitingNCT07910812Not applicable1 country
- Superficial Parasternal Block Combined With Rectus Sheath Block for Open Cardiac SurgeryNot yet recruitingNCT07890857Phase 41 country
- Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk FactorsRecruitingNCT067965821 country
- Serum Endogenous Estrogens, Estrogen Receptors, and Sirtuin-1 and -3 After Resveratrol SupplementationRecruitingNCT07865377Not applicable1 country
- Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or ObesityRecruitingNCT07657676Phase 41 country
- Evaluating New Radiation Techniques for Cardiovascular ImagingRecruitingNCT01621594Not applicable1 country
- NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)RecruitingNCT07820800Not applicable1 country
- Effectiveness of Pollution Monitoring in Clinical Exercise RehabilitationNot yet recruitingNCT07500948Not applicable1 country
- Exercise Training in Women With Heart Disease 2RecruitingNCT06494163Not applicable1 country
- Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT035813181 country
- The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart FailureRecruitingNCT070947371 country
- Intranasal Dexmedetomidine and Perioperative Myocardial Injury in Patients Having Percutaneous Coronary InterventionsNot yet recruitingNCT07847580Not applicable1 country
- A Cluster-Randomized Controlled TrialNot yet recruitingNCT07845448Not applicable
- Real-World Effectiveness and Costs of Yiqi Fumai Lyophilized Injection in Coronary Heart Disease-Related Chronic Heart FailureNot yet recruitingNCT078412751 country
- Yiqi Fumai Lyophilized Injection for Chronic Heart Failure Caused by Coronary Heart DiseaseNot yet recruitingNCT07803471Not applicable1 country
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable2 countries
- OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsRecruitingNCT07136012Phase 33 countries
- Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart DiseaseNot yet recruitingNCT00117936Phase 2
- Effectiveness of an AI-Enabled Stratified Management System for Premature Coronary Artery DiseaseRecruitingNCT07031531Not applicable1 country
- Single vs. Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Intervention With DCB-only Strategy (KONG-FREEDOM-I)RecruitingNCT07587099Not applicable1 country
- Construction and Validation of a Coronary Artery Disease-Specific Large Language Model and Its Evaluation Framework (CorAI)Not yet recruitingNCT077665511 country
- Intranasal Dexmedetomidine and Perioperative Myocardial InjuryNot yet recruitingNCT07549282Phase 41 country
- The Effect of Autonomic Neuropathy Status on the Endpoint Events in Diabetes Patients With Coronary Heart Disease and Sleep Apnea.Not yet recruitingNCT07723222
- Modifiable Risk Factors for Cognitive Dysfunction in Patients With Coronary Heart DiseaseRecruitingNCT076576241 country
- Trial of Orbital Atherectomy Versus Standard Strategy in Calcified Bifurcation LesionsRecruitingNCT06736899Not applicable1 country
- Evaluation of the First, Second, and New Drug-Eluting Stents in Routine Clinical PracticeRecruitingNCT011861331 country
- IRIS- DESyne X2 in the IRIS-DES RegistryRecruitingNCT035884811 country
- Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial ProspectiveNot yet recruitingNCT076637991 country
- Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac SurgeryRecruitingNCT076623171 country
- PK(Pharmacokinetic) Papyrus Covered Coronary Stent SystemRecruitingNCT06223633Not applicable1 country
- CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)RecruitingNCT07165678Not applicable1 country
- Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart DiseaseNot yet recruitingNCT07260552
- The International Survey of Acute Coronary Syndromes-ARCHIVESEnrolling by invitationNCT040081731 country
- The Effectiveness of a Theory-driven Behavioral Change Intervention on Sedentary Behavior in Individuals With Coronary Heart Disease: A Randomised Controlled TrialNot yet recruitingNCT07357961Not applicable
- Closed-Loop Neurofeedback Targeting the Left Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With AnxietyRecruitingNCT07244484Not applicable1 country
- Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With AnxietyRecruitingNCT07238920Not applicable1 country
- The Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Coronary Heart Disease: A Retrospective Cohort Study(CPETPCAD)Not yet recruitingNCT07534410
- CORE-COMPARE Pilot StudyRecruitingNCT06170541Not applicable1 country
- Multi-Omics-Based Novel Thrombosis and Bleeding Markers and Risk Model for CHDRecruitingNCT075238801 country
- Improved Management of Patients With Recent-Onset Stable Chest PainRecruitingNCT07476040Not applicable1 country
- CRIC Combined With MFT for MFR in Patients With Incomplete Revascularization of CADNot yet recruitingNCT07514624Not applicable
- A Study Evaluating the Vascular Healing and Neointimal Transformation at 1 Month After Implantation of BioFreedom™ Drug-coated Stents and the Xience Drug-eluting Stent System in Patients With Acute Coronary Syndrome and High Bleeding Risk Using Optical Coherence TomographyRecruitingNCT07230847Not applicable1 country
- Timing of Endoscopy in Coronary Heart Disease Patients Taking Antiplatelet Drugs With Acute Non-variceal Upper Gastrointestinal BleedingNot yet recruitingNCT07507162Not applicable
- A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart DiseaseRecruitingNCT07493603Phase 1/21 country
- Effectiveness of a Tele-cardiac Rehabilitation (Tele-CR) ProgramEnrolling by invitationNCT07110389Not applicable1 country
- Proteomic and Inflammatory Omics Changes With Colchicine Therapy in Coronary Heart DiseaseNot yet recruitingNCT07462325Phase 4
- Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)RecruitingNCT074518731 country
- Postprocedural Contrast Mediated FFR Plus Intracoronary Infusion of Nitroglycerin in Multivessel Patients (PROMETEUS TRIAL)RecruitingNCT06273293Not applicable1 country