Myocardial Reperfusion Injury clinical trials
The registry lists 57 studies for Myocardial Reperfusion Injury across more than 10 countries. 6 are recruiting or about to start. 35 of them are mainly about Myocardial Reperfusion Injury (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Who runs them
Xijing Hospital (4) · University College, London (3) · University of Chile (2) · University Hospital Birmingham (2) · Chinese PLA General Hospital (2) · Hospices Civils de Lyon (2) · Medical University of Vienna (2) · Beijing Tide Pharmaceutical Co., Ltd (1)
What is being tested here
Drugs under test in Myocardial Reperfusion Injury studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Empagliflozin | 1 | 0 | 2 |
| Dapagliflozin | 1 | 0 | 1 |
| Pioglitazone | 1 | 0 | 1 |
| Sevoflurane | 0 | 0 | 2 |
| Perhexiline | 0 | 2 | 2 |
| Carnitine | 0 | 0 | 1 |
| Nitric Oxide | 0 | 0 | 1 |
| Morphine | 0 | 0 | 1 |
| Methylprednisolone | 0 | 0 | 1 |
| Milrinone | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI · Ain Shams University
- Jan 2027Combined Antioxidant Therapy for Acute Myocardial Infarction · University of Chile
- Jun 2027Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCI · Al-Azhar University
Who these studies take
Of the 4 Myocardial Reperfusion Injury studies recruiting now, 2 (50%) set no upper age limit and 2 (50%) stop at 75 or younger. 1 (25%) take children under 18. 0 (0%) are for women only and 1 (25%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (25%) | 1 (25%) |
| 18 | 2 (50%) | 2 (50%) |
| 30 | 2 (50%) | 2 (50%) |
| 40 | 2 (50%) | 3 (75%) |
| 50 | 2 (50%) | 3 (75%) |
| 65 | 2 (50%) | 3 (75%) |
| 75 | 2 (50%) | 2 (50%) |
| 85 | 2 (50%) | 2 (50%) |
Across all 57 studies, recruiting or not: 33% stop at 75 or younger and 14% at 65; 16% take children; 0% are for women only and 2% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 57. Browse all 57 → or search them.
- Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCINot yet recruitingNCT07898709Phase 21 country
- Spectroscopic Assessment of Myocardial Oxygenation Changes in Pediatric Heart SurgeryRecruitingNCT077851411 country
- Combined Antioxidant Therapy for Acute Myocardial InfarctionNot yet recruitingNCT07776288Phase 21 country
- Remote Ischaemic Conditioning in STEMI Patients in AFRICARecruitingNCT04813159Not applicable6 countries
- Trans-coronary Cooling and Dilution for Cardioprotection During Revascularisation for ST-elevation Myocardial InfarctionRecruitingNCT06128993Not applicable1 country
- The Role of Pioglitazone in Vascular Transcriptional RemodelingRecruitingNCT05775380Phase 41 country
- Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary BypassCompletedNCT03500783Phase 1/2
- Morphine Versus Fentanyl for Myocardial Protection in Acyanotic Children Undergoing Congenital Open-Heart SurgeryCompletedNCT07839273Phase 41 country
- Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMIActive, not recruitingNCT06564909Phase 21 country
- Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical PatientsCompletedNCT05354648Not applicable
- Effective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac SurgeryCompletedNCT072494241 country
- Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial InfarctionCompletedNCT05462730Phase 21 country
- Novel Imaging Biomarkers for Mechanical Complications in Acute Myocardial InfarctionCompletedNCT064509121 country
- Post Cond No ReflowCompletedNCT01208727Not applicable1 country
- Delayed PostconditioningCompletedNCT01483755Phase 21 country
- MRI of Myocardial InfarctionCompletedNCT035311511 country
- Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial InfarctionCompletedNCT02098629Phase 21 country
- Investigation of Myocardial Protection Efficacy of Cardioplegia Solutions Used in Open Heart SurgeryCompletedNCT063735491 country
- Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19CompletedNCT043979391 country
- Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.CompletedNCT05215743Phase 11 country
- Sweat Analysis as Prognosticator After Heart AttackCompletedNCT058430061 country
- The Role of Colchicine in Reducing The Rate of Myocardial Reperfusion InjuryStatus unknownNCT05734612Phase 31 country
- Clinical Efficacy of Extracorporeal Cardiac Shock Wave Therapy in Patients With Ischemia-reperfusion InjuryStatus unknownNCT05624203Not applicable
- Remote Ischaemic Preconditioning in Childhood CancerCompletedNCT03166813Not applicable1 country
- Immunometabolic Pattern of Intermittent Hypoxia During ST-segment Elevation Myocardial InfarctionStatus unknownNCT05230966Not applicable
- Optimized Cardioprotection Therapy in Obese Subjects With AMIStatus unknownNCT045705141 country
- Effect of Remote Ischaemic Conditioning in Oncology PatientsStatus unknownNCT02471885Not applicable1 country
- Efficacy and Safety Evaluation of PC-SOD for Injection in Reducing Myocardial Reperfusion InjuryStatus unknownNCT03995732Phase 21 country
- Investigation Into the Role of GTN & RIPC in Cardiac SurgeryCompletedNCT01864252Phase 31 country
- Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)CompletedNCT02342522Not applicable4 countries
- The Protective Effects Of Treatment With Hyperbaric Oxygen Prior To Bypass Heart SurgeryCompletedNCT00623142Phase 1/21 country
- Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI PatientsStatus unknownNCT039393381 country
- The Role of Mitochondrial Respiration in the Cardioprotective Capacity of IPC in Diabetic and Non-diabetic PatientsCompletedNCT02993484Not applicable
- Cooling in Myocardial InfarctionCompletedNCT01777750Not applicable1 country
- Empagliflozin on Cardiac-renal Injury in Patients With STEAMI Patients After Primary PCIStatus unknownNCT03591991Not applicable
- Ciclosporin to Reduce Reperfusion Injury in Primary PCICompletedNCT02390674Phase 21 country
- Coronary Sinus Blood Sevoflurane and Desflurane Concentration and Lactate Changes in Patients Undergoing Heart SurgeryWithdrawnNCT02866630
- Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft SurgeryCompletedNCT02984111Not applicable1 country
- Effects of Melatonin on Reperfusion InjuryStatus unknownNCT03303378Not applicable1 country
- Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation SurgeryCompletedNCT02149316Not applicable1 country
- Cardioprotective Effects of GLP-1 and Their MechanismsCompletedNCT02128022Phase 11 country
- Myocardial Protection and Anesthetic AgentsCompletedNCT02405689Phase 41 country
- Intracoronary Darbepoetin-alpha to Reduce The Infarct Size and Post-Infarct RemodelingCompletedNCT01538771Phase 21 country
- Remote Ischemic Postconditioning in HumansCompletedNCT01113008Not applicable1 country
- Efficacy of Endovascular Catheter Cooling Combined With Cold Saline for the Treatment of Acute Myocardial InfarctionCompletedNCT01379261Phase 2/34 countries
- Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMICompletedNCT00586820Phase 21 country
- Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit)CompletedNCT01601795Phase 41 country
- ACCEL-LOADING-ACS StudyCompletedNCT01354808Phase 41 country
- Target Temperature Management In Myocardial Infarction - A Pilot StudyCompletedNCT01864343Not applicable1 country
- Remote Postconditioning in Patients With Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention (PCI)CompletedNCT00865722Phase 2/31 country