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Not yet recruitingNCT07833774Updated Sep 22, 2026

AI-enhanced Heart MRI for Evaluating Blood Flow

An observational study in Ischemic Heart Diseases, sponsored by IRCCS San Raffaele. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-22.

Sponsored by IRCCS San Raffaele · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
300
Ages
18 Years and older
Sex
All
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Study summary

This study will compare the standard MRI protocol with an advanced MRI protocol for the assessment of ischemic heart disease. The goal is to evaluate whether the advanced protocol provides comparable or improved diagnostic performance relative to the standard approach.

02

Conditions studied

  • Ischemic Heart Diseases

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03

In context

Myocardial Ischemia

1,123 studies on the registry are indexed under Myocardial Ischemia; 177 are open to participants now.

This study's planned enrollment of 300 is close to the median of 318 across 398 observational studies indexed under Myocardial Ischemia.

Browse Myocardial Ischemia studies →

Lead sponsor

IRCCS San Raffaele is the lead sponsor of 454 studies on the registry; 235 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Consecutive adults attending the U.O Advanced Imaging for Personalized Medicine to be submitted to stress cardiac MRI study

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Consecutive adults (≥18 y.o.) admitted to the UO for cardiac MRI with or without stress

Exclusion criteria

Exclusion Criteria:

  • Refused to consent
  • Claustrophobia
  • Metal prosthesis potentially affecting image quality
05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
300 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Interventions

  • Diagnostic testAccelerated advanced MRI sequences protocol

    The accelerated advanced MRI sequences will be compared with standard MRI sequences to evaluate their relative efficiency.

06

What researchers measure

Primary outcomes

  1. Noninferiority of accelerated advanced MRI sequences compared to standard MRI sequences, assessed using a paired Wilcoxon signed-rank test at a one-sided significance level of 0.025.

    Time frame: 3 years

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Sep 2026; primary completion for Aug 2027, 11 months later.

Of 165 non-industry observational studies under Myocardial Ischemia, half reached primary completion within 51 months of starting (the median), counting those still running; a quarter within 23 and three quarters within 127. This study's planned 11 months is below that.

Counting every sponsor, half of 204 studies reached it within 40 months; a quarter within 21 and three quarters within 90.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 16, 2026
First posted
Sep 22, 2026
StartEst.
Sep 1, 2026
Primary completionEst.
Aug 31, 2027
CompletionEst.
Aug 31, 2029
Last update
Sep 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07833774
Lead sponsor
IRCCS San Raffaele
Responsible party
Antonio Esposito (Director of U.O. Advanced Imaging For Personalized Medicine, IRCCS San Raffaele) — Principal investigator
First posted
Sep 22, 2026
Start date
Sep 1, 2026 (estimated)
Primary completion
Aug 31, 2027 (estimated)
Completion
Aug 31, 2029 (estimated)
Last update
Sep 22, 2026

Study contacts

Project manager
Contact
kavodnik.ekaterina@hsr.it
+390226438047

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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